Androgen receptor

it is then secreted into the blood where it regulates the functions of organs in the body, maintaining homeostasis. (Kraemer, Fleck, & Deschenes, 2012). Endocrine disruptors can mimic naturally occurring hormones in the body like the estrogen, androgen, and thyroid hormones, potentially producing overstimulation (Kraemer, Fleck, & Deschenes, 2012).…

CDH2 CDH2 gene codes for the protein N-cadherin, also known as Cadherin-2 (CDH2), or neural cadherin (NCAD). Studies on this gene has discovered that it is located on Chromosome 18-NC_000018.10, assembly GRCh38.p2 on humans, and contains 20 exons.(9) N-cadherin is one of the classification of the cadherin superfamily, and is composed of five extracellular cadherin repeats, highly conserved cytoplasmic tail and a transmembrane region. This protein’s purpose is to mediate cell-cell adhesion by…

(Carlson) believes that cases of aggression that are thought to be caused by high levels of testosterone can be treated with drugs that block androgen receptors and therefore stop androgens from causing their usual effects. It is believed that testosterone influences and increases activity in the amygdala, this may enhance a person’s irritability and cause them to be more aggressive, therefore by controlling testosterone…

Osteoporosis, otherwise known as porous bone, is characterized by a decrease in bone density as well as depreciation of bone tissue. Due to these conditions, there is an increased risk of bone breakages and fractures of the hip, spine, and the wrist. Both men and women are susceptible to osteoporosis; however, several preventative methods and treatments are currently out there. Here in the United States, approximately 40 million people are affected by the disease or have a higher susceptibility…

of the follicular phase, PGF2α secretion from the uterus causes the regression of the CL and progesterone concentrations rapidly decrease (Hansel and Convey, 1983). Luteinizing hormone binds to theca cells of the DF resulting in the synthesis of androgens that diffuse into the granulosa cells of the DF. Follicle stimulating hormone binds to the granulosa cells and increases aromatase…

It can also be used to prevent cancer in those who are considered high risk for the disease. MOA: The mechanism of action is nonsteroidal aromatase inhibition. Pharm effects: This leads to the pharmacological effects of blocking the conversion of androgens to estrogen, reducing the serum levels of estradiol. This helps decrease cancer cell growth by reducing the amount of hormone available to the cancer cells. Evidence: In this study, 84 breast cancer patients were assigned to 2 groups, with…

Junior Madubanya 12c Biology research task How do levels of oestrogen cause obesity in menopausal women and aging men The high levels of obese post menopausal women and aging men have caused much fascination and have led to in depth studies to determine whether oestrogen levels play a part in the elevating levels of obesity in patients of both genders. Obesity is an unhealthy accumulation of body fats which increases the risk of medical illnesses and is measured using the body mass index…

Performance-enhancing substances Performance-enhancing substances is one of the most important concerns for athletes till this day. These substances are outlawed in every league, but athletes still find a way to cheat and continue to find ways to get an edge over their competitors. These substances are used to improve performances of athletes and gives them an advantage. When taking these drugs it affects your body in many ways as growth of muscles but doesn’t change the fact that is is still…

Sociologist may associate biological influences on gender with the human behaviour and the structure of the human anatomy however; some sociologist may base their sociological influences on gender with cultural and environmental factors. This associates with the “nature vs. nuture” argument, as I will be exploring and comparing sociologist views on whether biology has more of an influence on gender or sociology. From a sociologist’s point of view, sex is referred to the biological approach and…

For my anatomy class I was asked to write a paper of how a body system of my choice affects the other body systems. I chose the endocrine system, it is made up of many different glands, but every gland still does a part in making sure that organs in the other body systems are well balanced. I liked the endocrine system when we went over it in class and thought it would be an excellent choice. Especially since most of it has to do with the brain and I love to study the brain. I will cover all the…