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343 Cards in this Set
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What is the generic of Aricept |
Donepezil
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What is MOA of Aricept
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Acetylcholineserase inhibitor (increase AcH by inhibiting its breakdown)
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What is Donepezil approved for treatment of
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MILD to SEVERE alzheimers dementia
ONLY one with indications for ALL types |
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What is the generic of Zestril
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Lisinopril
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What is the generic of Prinivil
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Lisinopril
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What is the generic of Vasotec
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Enalapril
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What is the generic of Altace
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Ramipril
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What is the generic of Lotensin
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Benazepril
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What are contraindications for ACE inhibitors
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Avoid is K >5
Avoid with angioedema (any pt) Bilateral artery renal stenosis Pregnancy D/C if Scr >0.3 |
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What are counseling pts (SE)
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Non-productive cough
Dizziness Avoid salt substitutes (since increase K |
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What is Flomax
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Tamsulosin
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What is MOA of Flomax
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Selective Alpha 1 antagoinst, in the prostate leads to relaxation of smooth muscle in the bladder neck, and prostate, which improved urinary flow
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Couseling pt for patients on Tamsuloxin (Flomax)
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May decrease BP, tell eye doctor, if getting cataract surgery
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What is generic of Catapres
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Clonidine
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What is MOA of Catapres
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Alpha 2 agoinst (stimulates alpha 2 receptors to DECREASE NE outflow (decrease PVR, HR)
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Counseling points for Catapres
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Risk of hypotension
avoid abrupt withdrawl |
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What is the generic of Namenda
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Memantine
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What is MOA of Namenda
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Blocking NMDA receptors (inhibits glutamate (an excitory NT)
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Role of Namenda
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moderate to SEVERE ALzheimers
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What is generic of Lidoderm
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Lidocaine
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What is MOA of Lidoderm
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inhbits depolarizations (decreases membrane permeability to sodium
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SE of Lidoderm patch
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mainly topical (ithcing depigmentation)
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Couseling pts with Lidoderm
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may use up to 3 patches on ONE area, leave on for up to 12 hours in any 24 hours period
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Can you cut Lidoderm patch
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YES, one of the few that can be cut!!
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What is the generic of Diovan
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Valsartan
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What is MOA of Diovan
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ARB (blocks ATII type 1 receptors, preventings vasoconstrtions, aldosterone release)
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What is generic of Cozzar
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Losartan
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What is generic of Benicar
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Olmesartan
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What is generic of Avapro
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Irbesartan
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Contraindications of ARB's
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same as ACE
Pregnancy Bilateral renal artery stenosis, Hyperkalemia |
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Couseling pts of ARBs
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hypotension, monitoring K, Scr, and avoid salt substitutes
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What is generic of Lanoxin
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Digoxin
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What is MOA of Digoxin
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increases intracelluar calcium to improve contractility
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Diogoxin is narrow TI drug, what is recommend goal
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0.5-0.8 for CHF
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What are signs/symptoms of Digoxin toxicity
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Halos around lights, N/V and EKG changes
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What is the reversal agents to Lanoxin
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Digibind
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Do you dose adjust with Digoxin
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YES--renally eliminated
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What is generic of Amoxil, Trimox
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Amoxicillin
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What is MOA
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Beta-Lactam inhbits bacteral cell wall syntheisis by inhibits transpeptidase
bacterialcidal |
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Main uses of AMOXCILLIN
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Otitis Media, Sinusitis dental procedures
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Can you give amoxillin in pregnancy
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YES, pregnancy B
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What is generic of Augmentin
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Amoxcillin/Clavulanate
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Do you need Augmentin for Step infections
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NO---Streptococcus do NOT make beta-lactamases
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What is generic of Tylenol #3
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APAP/Codeine
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What is schedule of T3
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Class III
or CV for solution |
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What is MOA of T3
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binds to mu-opioid reecptors
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Why is T3 not a very potent anagesic
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only 20-30% will get metabolized to morphine (codeine is pro-drug requring CYP2D6
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The T3 corresponds to how many mg of codeine
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30mg
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What is T2
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15 mg
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What is T4
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60 mg
for each number increase codeine doubles |
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What is generic of Detrol LA
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Tolerodine
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What is MOA of Detrol LA
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Anti-cholingeric
(atagonists urinary muscarinic recpetors that control muscle contraction |
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What are se of Detrol LA
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Anticholinerics SE
Burry visition, drug mouth, unirary rentention constipation |
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What is the generic of Spirivia
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Tiotropium
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What is MOA of Spirivia
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inhibits AcH resulting in broncodilation
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Tiotropium is once daily, how often is ipratropium
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4x
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What is generic of Atrovent
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Ipratropium
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Max dose of Atrovent
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12 puffs in 24 hrs
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Should you avoid Tiotropium and Ipratropium
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YES--both anticholingerics
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What is MOA of Coumadi
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inhibits activtion of vitamin K by VKOR (inhibit activton of 2, 7, 9, 10 and protein C and S
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Coumadin is a narrow therpeutic index drug, what are the main ways it interacts with other drugs
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inhibits CYP2C9
(Bactrim, Amiodarone) |
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What pregnancy class is coumadin
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X----very BAD
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What is the generic of Neurontin
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Gabapentin
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What is MOA of Neurontin
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Modulates activity of Na/Gaba
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What is generic of Lyrica
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pregabalin
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What is controll status of Lyrica
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CV
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Gabapentin/Pregablin is renally adjusted
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YES
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What is generic of Lamictal
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Lamotrigine
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What is MOA of Lamotrigine
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Blocks Na+
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What is couseling pt with Lamotrigine
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monitor for rash at least the first 8 wks of thearpy
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What is MAJOR DI with lamotrigine
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valproic acid
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What is the generic of Wellbutrin
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Bupropion
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What is generic of Zyban
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Buproprion (smoking cessation
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What is MAJOR contraindication of Buproption
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seizures and eating disotrders
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What is MOA of Bupropion
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inhibits reuptake of DA and NE (increases)
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What Antidepressant does NOT cause sexual dysdunction
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bupropion
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What are the brand names of Albuterol
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ProAir
Ventolin Proventil |
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What is MOA of Albuterol
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B2 agoinst (binds to recpetors on broncial smooth muscle causing relaxation
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What is generic of Foasmax
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Alendronate
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What is MOA of Fosamax
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Bisphophosnate
Inhibits osteoclast activity |
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Why must Fosamax be taken with 8oz of water 30 minutes before food/drink and remain upright for 30 minutes
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risk for esophagitits and poor absorption
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What must also be supplemented with Fosamax
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Calcium/Vitamin D
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What CrCl should Bisphophnates be avoided in
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CrCl <35
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What is the generic of Zyloprim
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Allopurinol
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What is MOA of Allopurinol
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Xanthine Oxidase inhibitor
(inhibits uric acid syntheisis) |
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What is role of Allopurinol
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only use for prevention of gout
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What is a MAJOR DI with Allopurinol
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Azathioprine
causes major bone marrow suppresion |
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What do you monitor for with Allopuriol
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skin rash/hypersenstivity
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What is generic of Xanax
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Alprazolam
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What is MOA of Xanax (Alprazolam)
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GABA agoinst
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What length of time should Xanax no longer be abruptly discontinued
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>3-4 weeks will cause withdrawl
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What should you counsel to avoid use with
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alcohol
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What is pregnancy category of Xanax (Alprazolam)
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Pregnancy D
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What is generic of Elavil
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Amitriptyline
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What is MOA of Elavil
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TCA (inhibits reuptake of 5HT and NE
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What are common SE of Elavil
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Anticholingeric (blurry vision, dry mouth, constipation, urinary retention)
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Is Elavil a Beer's List medication
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YES
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What is generic of Norvasc and Class
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Amlodipine (Dihydropyridine CCB)
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What is MOA of Norvasc
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Dihydropridine CCB (blocks Ca+ entry into vascular smooth muscle leading to vasodilation
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What is the preferred CCB in ESRD/Dialysis
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Amlopdine (nor renally elimiated)
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What is generic of Lotrel
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Amlodpine/Benazepril
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What is MOA Lotrel (Amlodpine/Benazepril)
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ACE I and CCB
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What is generic of Abilify
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Aripiprazole
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What MOA of Abilify
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Atypical antipsyychotic
Partial agoinst of D2, and 5HT receptors |
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How is Abilify supplied
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Tablet, ODT, oral solution, IM
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What should you monitor for with Abilify
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LIpids, Glucose, acathisia
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What is generic of Tenormin
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Atenolol
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What is MOA of Tenormin
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Selective Beta 1 Blocker
Blocks binding of NE to receptors in heart and Kindey, |
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Is Tenormin FDA approved for HF
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NO
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What should you monitor for with Tenormin
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BP, HR
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Tenormin (Atenolol) is a hydrophilic beta blockers and thus
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renally eliminated
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What disease states should Beta blockers be used in caution with
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PVD or claudicaiton
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How much can Lipitor (Atrovastatin) lower LDL cholesterol
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50-55%
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What should you moinitor while on Lipitor
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LFT (hold >3x ULN), S/S myopathy, Rhabo, Lipids
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Drug intearctions with Lipitor
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Drugs that inhibit CYP3A4 (Azoles, Ery-Tab, Clarthromiycin)
PI---ok in low dose 10mg |
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What is Pregnancy Cateory of Lipitor
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X
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What is gneric of Zmax or Zithromax
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Azithromycin
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What is drug class of Aithromycin
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Macrolide
Binds to 50S ribosomal subnits and inhibits protein synthesis |
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How is Azithromycin supplied
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Tablet, Suspension, IV
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What is main role of Macrolides
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Chalmydia, MAC, URI
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Can you replace Zpak for clarithromycin in H Pylori
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NO
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Does ZPak have any drug interactions
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NO---think Clarithromycin
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What is generic of Suboxone
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Buprenoprhine/Naloxone
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What is control of Suboxone
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CIII
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Why is Suboxone formulated with Naloxone
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so if try to use by IV, naloxone would antagoinst opioid receptors
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How is Suboxone taken
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sublingually
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What is role of Suboxone
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maintenance treatment of opioid dependence
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Who can prescribed suboxone
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only prescribeers with an X
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What eye ointment is used on all babies at birth
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Erythromycin
prevent opthalmia neonatorum |
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What is generic of Soma
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Carisoprodol
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What is MOA of Soma
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Skeletal muscle relaxant
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What is generic of Coreg
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Carvediolol
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What is MOA of Coreg
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Non-selective BB, and alpha 1 blocker
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Carvediolol IR is dose BID, what CR is dosed
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once daily
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What is starting dose of Carvediolol for heart failure
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3.125 mg BID, and tirtrate every 1-2 weeks to avoid causing decompensations
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What is goal tirtation of Carvediolol in HF
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25 mg BID
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What should you mointor on Carvediolol
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HR, BP
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What is generic of Celebrex
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Celecoxib
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What is MOA of Celebrax
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Selective COX-2 inhibitior
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What allergy should Celebrex be avoided in
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SULFA allergy
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Who should Celebrex be used in caution with
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CV disease, HF, HTN, GI or renal disease
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Keflex is only available as
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oral formulation
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What is MOA/Drug class of Keflex
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Beta-Lactam, 1st generation Cephalosporin
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What is MOA of Cipo (Ciprofloxacin)
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Floroquinolone
Inhibits DNA gyrase preventing DNA replication and repair |
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What are 2 Floroquinolones that cover Pseduomonas
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Levofloxacin, Ciprofloxacin
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When do you renal dose Fluorquinolones
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CrCl <50
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What is major couseling point with floroquinolones
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avoids di or tri-valent Cations (Ca+, Mg)
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Should you avoid flouoquinolones in pregancy
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YES, C
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What is generic of Celexa
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Citalopram
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How long does Celexa take before efficacy
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3-4 weeks
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What SSRI has the least DI
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Citalopram
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Is sexual dysfunction a common problem with SSRI
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YES
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Should you avoid aburpt DC of all SSRI
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YES
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What is generic of Klonopin
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Clonazepam
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What is generic of Plavix
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Clopidogrel
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What is MOA of Plavix
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Anti-platlet
Blocks ADP on prevetion, preventing platlet aggregation |
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What is monitoring with Plavix
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signs/symptoms of bleeding
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Plavix is a pro-drug what is problems
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DI---especially PPI (omeprazole/lansoprazole) or any drugs that inhibit CYP2C19
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What should patient also get with getting stent in addition to Plavix
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ASA (12 moths DES)
1 month for BMS |
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How long should plavix be stopped prior to CABG
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5 days becuase increase risk of bleeding
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What is generic of Premarin
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Conjugated Estrogen
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What is role of Premarin
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hot flash control, and symptoms of menopauses
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Conjugated estrogens should be use at the lowest dose and shortest duration, what are contraindications
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VTE, vascular disease, hx of breast cancer
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Flexeril (Cyclobenzaprine) MOA
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Skeletal muscle relaxant, ALSO inhibitts 5HT NE uptake
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Cyclobenzabrine is sturucally similar to TCA, so increase risk for
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serotonin syndrome
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What are common SE of Cycloenzprine
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Sedation, drowiness--avoid alcohol
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What is generic of Adderall
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Dextoamphetamine
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WHat is MOA of Adderall
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Stimulant (Blocks reuptake of NE/DA, and stimulates CNS
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What is monitoring for Adderall
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appetits, weight, BP, HR
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What is the generic of Vibramycin?
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Doxycycline
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What is the generic of Doryx?
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Doxycycline
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WHat is MOA of Doxycycline
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Tetracycline
inhbits 30S ribosome, inhibiting protein synthesis |
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Can Doxycycline be used for MRSA infections
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YES, outpatients
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What age must children be to use tetracycline and why NOT used in pregnancy!
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>8 yrs becuase causes yellowing of teeth
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What are the MAJOR DI with Tetracycline
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Chelate avoid taking with antacids, Ca, Ma, iron (decrease absoprtion)
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What is generic of Yaz
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Dorspirenone/EE
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What drug class if YAZ
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COC
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Who should avoid Combined oral contraceptives
|
pts who smoke and >35, history of DVT, or hypercoagulale
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WHat is Drospirenone derived from
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Sprionolactone (anti-androgeneic) watch out for HyperKalemia
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What is generic of Cymbalta
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Duloxetine
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WHat is MOA
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SNRI
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What are role of Cymbalta in treatment
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GAD, Depression, neuropathic pain, fibromyalgia muscleskeltal pain
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What is Monitoring of Cymbatla
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BP (SNRI)
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What are major DI with PPI
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avoid with itraconazole, ketoconazole, and atazanavir
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What is generic of Lunesta
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Eszopiclone
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What is drug class of Eszopicolone (Lunesta)
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Gaba like agoinst
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What is couseling points with Lunesta
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unpleasant tase, avoid other CNS deperssants
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What is generic of Zetia
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Ezetimibe
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What is MOA of Zetia
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cholesterol absorption inhibitor
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What is negative to using Zetia
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no data available to support decreased mortaility
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What are the brand names of Fenofibrate
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Tricor, Triglide, Fenoglide, Lofibra
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What is MOA of Fenofibrate
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Fibric acid dervative or PPAR-alpha
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What are CONS of Fenfibrate
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NO mortality data supporting use
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Does Fenofibrate have drug interactions with statins like gemfibrozil
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NO
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What is generic of Allegra
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Fexofenadine
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What is MOA of Allegra
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H1 antagoinst (2nd generation)
does NOT cross the BBB, so minial sedation |
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What is generic of Diflucan
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Fluconazole
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What is MOA of Diflucan
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Inhbits Ergosterol synthesis
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What is the main role if Diflucan
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vaginal yeast infections (1x dose)
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What are MAJOR DI with fluconazole
|
CYP2C9, and CYP3A4
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What does Prozac a strong inhibitor of, and why problem
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CYP2D6, avoid use with atomoxetine, tramadol, tamoxifen
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What is generic of Flovent HFA
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Fluticasone
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What is improtant couseling point prior to use of Flonase (Fluticasone)
|
Clear Nasal passages before dose is given
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What is generic of Advair
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Fluticasone/Salmeterol
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What is MOA/Drug Class
|
Inhaled Corticosteriod/LABA
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What vitamin is Folic Acid
|
B9 (water soluble vitamin)
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What is main role of folic acid
|
pregancy prevents spina bifida
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What is MOA of Lasix
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Inhibits Na/K+ symporter in the Loop of Henle
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What do you monitor on Lasix
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BP, Electrolytes (K, Mg, Ca, Na)
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Does Gabapentin require renal dosage adjustment
|
YES
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What is generic of Glynase or Diabetea, Micronase, PresTab
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Glyburide
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What is MOA of Glynase (Glybrudie)
|
Sulfonylurea (Binds to the Sulfonlurea receptor on pancreatic beta stimuates and stimulates glucose INDEPENDENT insulin secretion
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What are adverse effect of Diabeta
|
hypoglycemia, weight gain
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What CrCL should you avoid Glyburide
|
<50ml
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What is generic of Cheratussin AC
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Guaifensein/Codeine
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What is Class/MOA
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Expectorant/Cough Suppresant
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Codeine plays the role as cough suppressant, what cough is it not recommended
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productive
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What is generic of Microzide or Esidrix
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HCTZ
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What is MOA of Microzide (HCTZ)
|
Inhibits Na/Cl symporter in DCT
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Who should avoid be treated with HCTZ
|
patients with gout (increase uric acid levels)
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What is generic of Lortab/Vicodin
|
Hydocodone/APAP
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What control level is Vicodin
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CIII
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What is Hydrocodone metabolized to
|
Hydromorphone (Dilaudid)
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What is generic of Ismo, MonoKet
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Isosorbide Mononitrate
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What is MOA of Imdur/Ismo
|
Vasodilator
relaxes smooth smooth (reduces preload) |
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What formulation of Isosorbide is dosed BID
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Mononitrate
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What formulation is once daily
|
Imdur
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SE of Isosorbide
|
Hypotension, HA, dizzines
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WHat is MAJOR DI with Isosorbide
|
not to use with PDE-5 inhibitors because of profound risk for hypotension/shock
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What is generic of Xalatan
|
Latanoprost
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What is MOA of Xalatan
|
Antiglucoma/prostaglandin analog
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Xalatan is eye drop applied once daily for glaucoma, what are SE
|
changes color of the eye, eyelid and/or eyelashes
|
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What is generic of Synthroid, LEvoxyl
|
Levothyroxine
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What is MOA of Levoxyl
|
Synthetic T4
|
|
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What is monitoring of Levoxyl
|
TSH after 6-8 weeks after starting or DOSE change
|
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Levoxyl is ideally taken once daily on empty stomach prior to breakfast, however what should they always avoid
|
Ca/Mg Ir, and binds
|
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What is generic of Vynase
|
Lisdexafetamine
|
|
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What is MOA of Vyvanse
|
Stimulate (stimulates release of NE and DA)
|
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What is generic of Zestoretic
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Lisinopril/HCTZ
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What is generic of Ativan
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Lorazepam
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Ativan is benzodiazepine, what are role for treatment
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Anxeity, status eplieticus, alcohol withdrawl
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What is generic of Hyzaar
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Lorsartan/HCTZ
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What is generic of Mevacor
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Lovastatin
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What are the big drug interactions with Mevacor
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major CYP3A4 substrate, interaction with inhibitors
Verapamil, amiodarone, PI, Azole/Ery-tab, Clarthromycin, |
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What is generic of Antivert
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Meclizine
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What is MOA of Antivert
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1st generic antihistamine/antimetic
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What is role of meclizine
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motion sickness, dizziness, morning sickness
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What is generic of Mobic
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Meloxicam
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What MOA of Mobic
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NSAID (more cox 2 selective)
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How often is Mobic doses
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ONCE daily
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What do you monitor on Mobic
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BP, Renal function, Gastritics,
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Who should NOT take NSAID
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prior ulcers, renal failure, HF, and uncontrolled HTN, pregancy (especially 3rd trimester)
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What is generic of Glucophage, Fortamet
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Metformin
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What is MOA of Glucophage
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Biguanide, inhibits hepatic glucose production, and improves insulin senstivity
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What are contraindications of Glucophage
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Cr 1.5 or greater in men and Cr 1.4 or greater in women, and IODINATED contrast
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WHat is generic of Concerta
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Methylphenidate
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What is MOA of Concerta
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Stimulate (increase DA/NE
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What is generic of Medrol
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Methylprednisolone
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What are SE of Medrol
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Edema, hyperglycemia, osteoprosis, cataracts, ulcers, impaired wound healing, CNS stimulation, avascular necrosis (bone breaking off )
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What is generic of Toprol
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Metoprolol Succinate
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What is generic of Lopressor
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Metoprolol Tartarte
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What is generic of Nasonex
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Mometasone
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What is generic of Mobic
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Meloxicam
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What is MOA
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NSAID (COX inhibitor) more seleective COX-2 inhibition
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What is generic of Singulair
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Montelukast
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What is MOA of Singulair
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Luekotriene receptor antagoinst
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Singular comes in regular and chewable tablets
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YES
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What age can peds start Singulair
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6 months, and 12 months
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What is generic of Niaspan
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Niacin
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What is the major SE of Niaspan and how to treat
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Flushing, decrease with taking 325 mg ASA 30 minutes before doase
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What is Adverse Effects/Cautions with using Niaspan
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Increases uric acid, and glucose levels, and monitor LFTs
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What is generic of Zyprexa
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Olanzapine
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What is MOA of Zyprexa
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Dopamine and 5HT antagonist, and also antagoinst activity on histamine
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What are adverse effects of Zyprexa
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WEIGHT, cardio-metabolic effect
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What is generic of Benicar
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Olmesartan
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What is MOA of Benicar
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ARB, inhbit ATII receptor 1
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What is generic of Benicar HCT
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Olmesartan/HCTZ (ACE/ARB)
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What is the generic of Lovaza
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Omega 3 fatty acid
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What allegry should pts avoid Lovaza
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Shellfish/fish
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What is generic of Tamiflu
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Oseltamivir
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What is MOA of Oseltamivir
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Antiviral (neurmainidase inhibitor)
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Tamiflu treats both influenza A and B, and is effective for both treatment/prophylaxis if begun within - hours of onset/exposure
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48 hours
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Treatment of Tamiflu duration
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5 days
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What is prophylaxis of Tamiflu duration
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10 days
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What is generic of Oxycontin
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Oxycodone ER (IN means extended release)
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What is generic of Percocet
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Oxycodone/APAP
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What is controlled status of Percocet/Endocet/Tylox
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CII
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What generic of Paxil
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Paroxetine
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Paxil is a strong inhibitor of CYP2D6 so caution with the following medications
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Atomoxetine, tramadol, and tamoxifen
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What is the only SSRI that is preganacy category D
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Paxil
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What is generic of Actos
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Pioglitazone
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What is MOA of Actos
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TZD (PPAR-Gamma)
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What are cautions/adverse effects of Actos
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Peripheral edema, weight gain, and containdicated in Class III/IV HF, and increase fracture risk
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What is generic of Pravachol
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Pravastatin
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What is generic of Phenergan
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Promethazine
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What is drug class of Phenergan
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Antiemetic/1st generic antihistamine
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How can Phenergan be given
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ORALLY (also elixir), IM, IV
NOT SUBQ |
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What are SE of Phenergan
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sedation/drowsiness, and CNS depression, pseduoparkinsonism, and anticholingeric SE
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What is generic of Seroquel
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Quetiapine
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What is MOA of Seroquel
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Atypical antipsychotic
antagoinism of 5HT/DA |
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Role of Seroquel
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Bipolar, SCZ, and ICU delirium
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What is BBW of Seroquel as well as other antipsychotics
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warning use in elderly with dementia increases mortality
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What is generic of Aciphex
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Rabeprazole
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What is MOA of Aciphex
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PPI (inhibits H/K_ ATPase pump0
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What is generic of Evista
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Raloxifene
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What is MOA of Evista
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Selective estrogen receptor modulators (agoinst of estrogen receptor on bones (ANTAGONIST on uterus/breast)
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Raloxifene (Evista) can be used for osteoporosis, but also commonly used for what
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decrease risk of invasive breast cancer
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What are cautions/contraindications with use of Evista
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History of VTE/Breast cancer
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What is generic of Altace
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Ramipril
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What is generic of Zantac and MOA
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Rantidine H2 antagonist
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What happends during M phase.
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M phase (cell division), mitosis and cytokinesis occur, producing two daughter cells.
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What is generic of Actonel
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Risdronate
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What is MOA Actonel
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Biphosphonate
Inhibits osteoclast activity |
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What is generic of Crestor
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Rousvastatin
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What is generic of Sertraline
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Zoloft
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What is generic of Vigara
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Sildenafil
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What is MOA of Viagra
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PDE 5 inhibits
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Viagra is contraidicted in with what other day
|
nitrates!!
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What is generic of Zocor
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Simvastatin
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What is MOA of Zocor
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HMG co reductase inhibit
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Zocor should be avoided with what other drug
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PI, verampil, amiodarone, gemfibrozil, Azoles, Ery, Clarithromycin
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What is generic of Vytorin
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Simvastatin/Ezetimibe
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What is generic of Januvia
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Sitagliptin
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WHat is MOA Januvia
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DDP-IV inhibitor
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Bactrim MOA
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Inhibits folic acid synthesis, and DHFR
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Bactrim is DOC in what type if HIV pts
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PCP
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Should Bactrim be avoided in pts with G6PD
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YES can cause hemolysis and jaundice, fatigue
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What is generic of Cilalis
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Tadalafil
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What PDE-5 inhibitor has a long-half life
|
Cilais/Tadalfil
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What is generic of Ultram
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Tramadol
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|
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Should tramadol be avoided in pts with seizures?
|
YES
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What is MOA Trazadone
|
Serotoin reuptake inhibtior
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What is generic of Maxzide/DYazide
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Triamterene/HCTZ
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|
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What is MOA Maxzide/Dyazide
|
Thiazide and K+ sparring diuretic
|
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What is generic of Valtrex
|
Valacyclovir
|
|
|
What is MOA Valtrex
|
inhibit viral DNA synthesis
|
|
|
Valtrex is a progdrug of
|
Acyclovir
|
|
|
What is generic of Diovan HCT
|
Valsartan/HCTZ
|
|
|
What is generic of Calan SR
|
Verapamil
|
|
|
What is MOA of Calan SR
|
CCB (NON-dihydropyridine)
|
|
|
Why is Verapamil contraindicated in HF
|
decrease inotropy
|
|
|
What are SE of Verapamil
|
constipation, peripheral edema
|
|
|
Are there drug interaction with Verapamil, why
|
substrate and inhibitor of CYP3A4
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