Cole 1

Front 1

"movement disorder"

Back 1

basal ganglia

Front 2

UMN

Back 2

cortex, subcortex, brainstem, spinal cord

Front 3

LMN

Back 3

anterior horn cells, nerve roots, plexus, peripheral nerves

Front 4

duchennes

Back 4

x-recessive

Front 5

myotonic dystrophy

Back 5

autosomal dominant

Front 6

deletion/duplication at Xp21

Back 6

duchennes

Front 7

CTG nucleotide repeat at chromosome 19

Back 7

myotonic dystrophy

Front 8

prognosis of GBS

Back 8

stabilize after 3 weeks because schwann cells re-myelinate

Front 9

Tx GBS

Back 9

IVIG/plasmapharesis

Front 10

Dx GBS

Back 10

-EMG: conduction blocks* with slow velocity

-high CSF protein (demyelination of nerve roots)

Front 11

Schwann cells myelinate:

Back 11

PNS (GBS, charcot marie)

Front 12

oligodendrocytes myelinate:

Back 12

CNS (MS)

Front 13

where along the nerve are Na channels at the highest?

Back 13

-initial segment & node of Ranvier

Front 14

what type of reflex are muscle stretch reflexes?

Back 14

MONOSYNAPTIC (initiated by activation of muscle spindles)

Front 15

pain at digits 1-3 and weak thumb, that AWAKENS PATIENT FROM SLEEP*

Back 15

median nerve entrapment at wrist

Front 16

weak hand, numb digits 4-5

Back 16

Ulnar nerve entrapment at elbow

Front 17

Saturday night palsy

Back 17

Radial entrapment at *SPIRAL GROOVE

Front 18

Honeymooner's palsy

Back 18

Radial entrapment at *AXILLA

Front 19

wrist drop

Back 19

radial nerve entrapment

Front 20

wrist drop but TRICEPS OK, where is the radial nerve entrapment?

Back 20

At spiral groove*

Front 21

Pb toxicity

Back 21

radial nerve entrapment

Front 22

weak foot DORSIFLEXION (foot drop) & loss of sensation at 1st/2nd toes

Back 22

fibular nerve entrapment

Front 23

3 types of foot drop

Back 23

1. fibular nerve

2. L5 radiculopathy

3. ALS

Front 24

foot drop, pure weakness, sensation intact****

Back 24

ALS

Front 25

what are the muscles supplied by the fibular nerve?

Back 25

-tibialis ANTERIOR (foot dorsiflexion)//footdrop

-peroneus longus (foot eversion)

Front 26

patient has paresthesias of lateral leg and dorsum of foot, has foot drop, and radiating back pain, what else can you expect with L5 radiculopathy?

Back 26

-poor hip abduction (gluteus medius)

-poor knee flexion (hamstrings)

-poor foot in*version (posterior tibialis)

Front 27

CMAP

Back 27

motor nerves

Front 28

SNAP

Back 28

sensory nerves

Front 29

what results in reduced amplitude of CMAP?

Back 29

-AHC, root, plexus, axonal neuropathy

Front 30

reduced snap

Back 30

-lesions DISTAL to DRG (plexus/periphearl nerve)

Front 31

lesions PROXIMAL to DRG (radiculopathies) do what to SNAP?

Back 31

UNCHANGED

Front 32

conduction block*** on nerve studies

Back 32

GBS or carpal tunnel***

Front 33

slowed conduction velocity***

Back 33

demyelinating** polyneuropathy

Front 34

spontaneous discharge of INDIVIDUAL muscle fibers

Back 34

fibrillations (can only be seen in lab)

Front 35

spontaneous discharge of individual MOTOR UNITS

Back 35

fasciculations (can be seen VISUALLY by looking at the skin!!!)

Front 36

in what type of dz will you see LARGE AMPLITUDE MUPs on EMG?

Back 36

CHRONIC neurogenic conditions

Front 37

LARGE amplitude MUPs

Back 37

anything involving LMN (AHC, etc): adjacent*** previously denervated* muscle fibers are RE-INNERVATED....takes time to develop (so only seen in chronic conditions)

Front 38

when you increase the force of muscle contraction in CHRONIC neuro dz, recruitment* of additional motor units is DECREASED, why?

Back 38

fever numbers of motor units

Front 39

reduced amplitude of MUPs

Back 39

MYOPATHIES

Front 40

Why is there a random, scattered DROP out of individual muscle fibers from all motor units in myopathies?

Back 40

the muscle fibers in each motor unit are randomly lost, resulting in fewer muscle fibers per motor unit