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25 Cards in this Set

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What type of hypersensitive reaction is an asthma attack?

Type 1 hypersensitivity reaction (IgE antibody mediated reaction)

What is asthma?

Chronic inflammatory disorder of the lungs

What are the main characteristics of asthma?

- wheezing


- dyspnoea


- cough


- chest tightness

What are the 3 main pathological events that occur during an asthma attack?

1) Bronchial smooth muscle spasms: clamps down on the airway


2) Mucosal oedema: vasodilation and increased capillary permeability is a response of cytokines release and causes the mucosal layer to swell


3) Increased production of mucosa by the the mucosal glands

What are some signs that a person is having an asthma attack?

1) dyspnoea


2) expiratory wheeze


3) cough


4) chest tightness


5) tachycardia


6) tachypnoea

What are some signs of severe episodes of asthma attack?

- wheeze on both expiration and inspiration


- use of accessory muscles

What is pulsus paradoxus?

Exaggerated decrease in systolic blood pressure during inspiration

What are the typical arterial blood gas findings seen in acute asthma?

- hypoxaemia (decreases Pa02)


- hypocapnia (decreased PaC02)


- respiratory alkalosis (blood pH level above 7.45

A person’s breathing during an asthma attack would be characterised by?

Expiratory wheeze

What is the gold standard test for diagnosis and monitoring of asthma?

Spirometry

What does spirometry measure?

How much and how quickly air can be expired from the lungs

What is status asthmaticus?

Asthmatic episode that does not respond to medications

What position would you place someone in who is having an asthma attack to assist with their breathing?

High fowlers (head of bed raised to 40-90 degree angle)

What is the most earliest sign of an asthma attack?

Anxiety

What is hypoxemia?

Low level of oxygen in the blood

What signs would indicate a patient may have hypoxaemia?

Anxiety


Restlessness


Confusion

What steps would you take to improve patient status during an asthma attack?

1) administer prescribed fast acting bronchodilator


2) administer supplemental oxygen to achieve o2 saturations above 90%


3) administer systemic corticosteroids

How do fast acting bronchodilators work?

They relieve bronchoconstriction by blocking beta-2 agonists causing relaxation of bronchial smooth muscle

How do systemic corticosteroids work?

By reducing airway inflammation

What is an example of a fast acting bronchodilator?

Salbutamol

What is an example of a systemic corticosteroid?

Prednisone

A complication of chronic asthma is?

Pneumothorax

How do reliever medications work?

- Provide acute relief of symptoms


- relieve bronchoconstriction by blocking beta-2 agonists which relaxes bronchial smooth muscle


- examples: salbutamol and terbataline

What are some side effects of salbutamol?

- muscle tremors or shaky


- headache


- nervousness


- muscle cramps

How does aminophylline work?

Same as fast acting bronchodilators - relieves bronchoconstriction by relaxing bronchial smooth muscle to cause bronchodilation