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21 Cards in this Set
- Front
- Back
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Transfusions (Packed RBC) |
Taking just the red blood cells from the donor, just the erythrocytes. (The plasma is removed, along with the WBC and the platelets) |
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Why do we give (a packed) RBC? |
To restore oxygen carrying capacity |
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Incompatible blood transfusion |
When blood donated has a negative outcome on the person who received the blood. |
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What is on the surface of our RBCs |
Glycoprotein antigens |
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Agglutination |
When antigens that are not compatible begin to clump together. |
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Agglutinogens (a.k.a antigens) |
antigens that can cause agglutination (the clumping of RBC) |
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Blood type ABO refers to ________ |
Refers to the type of antigen on the RBC surface |
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Antibodies that bind to foreign RBCs do what? |
Mark the cell for destruction |
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Why do we produce antibodies? |
You produce for things you don't have. (They float in the plasma) |
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Agglutinins |
known as antibodies |
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What's the difference between the Glycoprotien "A" the Glycoprotein "B" |
The shape of the glycoproteins are going to be different |
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Can antibodies bind to any shape? |
No antibodies can only bind to a specific shape. Each of our antigens have a specific shape, which means there are diff type of antibodies for each of the antigens. |
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Which region in antibody differ between an anti A or an anti B antibody |
The variable region |
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Constant region |
The same within the same class of antibodies but different when it comes to different classes of antibodies |
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Type AB Blood is the universal ___________ |
Recipient, no antibodies to attack other groups |
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Type O Blood is the universal ___________ |
Donor, no antigens to be targeted |
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Rhesus Factor |
+/- (D antigen), the +/- tells us if the Rh factor is present or not |
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For example Blood type A- would mean _______ |
On the blood cell surface they have A antigens but they are negative for Rh |
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When do make an antibody? |
An antibody is made when there is a threat to the body, made to fight a specific invader. (Antibodies are not preformed) |
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Anti Rh is only made when _____ |
You have been exposed to it at some point. |
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Why don't we care much about the other antigens on the RBC surface? |
When antibodies bind to them there is no negative reaction, it will not cause clumping or a strong negative reaction |
