Because it is a type of cancer and people scared from any type cancers, because sometimes it leads to death. Melanoma affecting the patient negatively in several ways, because it affects the appearance of the patient. For example, it affects the patient’s body through the changes that occur in the skin such as the moles, and spots. Furthermore, it may affect the psyche and neurons of the patient and cause Psychological problems such as depression, anxiety, and neurological problems. In addition, melanoma also affects the patient's health in several forms such as weight and muscle loss. Similarly, it causes problems in the digestive system. For example, anorexia (loss of appetite), nausea (vomiting), fatigue, Mouth and throat problems. Loss of muscle and weight, and anorexia occur because of the generated of cytokines when the body tries to eliminate the cancer. Some treatments for melanoma affect the patients in different ways. For instance, in chemotherapy patients experience hair loss, diarrhoea, nausea, and their immune system becomes weak and can be infected by any infectious. Additionally, Radiotherapy also affects the patient during the period in which patients will receive treatment such as “the skin may become slightly red and sore during the treatment period, like a mild to moderate sunburn.”[4] The effectiveness and the development of melanoma can be managed by managing or inhibiting the mutated gene which is in BRAF, gene that regulated the cell signalling and division of the cells. BRAF when it has a mutation can be managed or inhibited by using BRAF inhibitors in the coding of ERK,RAF, and MEK, which is a pathway included BRAF in their
Because it is a type of cancer and people scared from any type cancers, because sometimes it leads to death. Melanoma affecting the patient negatively in several ways, because it affects the appearance of the patient. For example, it affects the patient’s body through the changes that occur in the skin such as the moles, and spots. Furthermore, it may affect the psyche and neurons of the patient and cause Psychological problems such as depression, anxiety, and neurological problems. In addition, melanoma also affects the patient's health in several forms such as weight and muscle loss. Similarly, it causes problems in the digestive system. For example, anorexia (loss of appetite), nausea (vomiting), fatigue, Mouth and throat problems. Loss of muscle and weight, and anorexia occur because of the generated of cytokines when the body tries to eliminate the cancer. Some treatments for melanoma affect the patients in different ways. For instance, in chemotherapy patients experience hair loss, diarrhoea, nausea, and their immune system becomes weak and can be infected by any infectious. Additionally, Radiotherapy also affects the patient during the period in which patients will receive treatment such as “the skin may become slightly red and sore during the treatment period, like a mild to moderate sunburn.”[4] The effectiveness and the development of melanoma can be managed by managing or inhibiting the mutated gene which is in BRAF, gene that regulated the cell signalling and division of the cells. BRAF when it has a mutation can be managed or inhibited by using BRAF inhibitors in the coding of ERK,RAF, and MEK, which is a pathway included BRAF in their