Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
What reactions need ATP?
|
(1) glucose --> glucose-6-P
(2) fructose-6-P --> fructose- 1,6-bisphosphate |
|
What reactions produce ATP?
|
(1) 1,3-bisphosphoglycerate
--> 3-phosphoglycerate (2) phospoenolpyruvate --> pyruvate |
|
What reaction require NAD+?
|
glyceraldehyde-3-phosphate
--> 1,3-bisphosphoglycerate |
|
What are the two possible metabolic fates of pyruvate?
|
(1) Produce ethanol
(2) Produce lactate |
|
What is the committed step of glycolysis?
|
The formation of fructose-1,6- bisphosphate.
|
|
What are the metabolic effects of not being able to produce the M subunit of phosphofructokinase?
|
Glycolysis will carry on in the liver but patients would experience muscle weakness.
|
|
How does ATP act as an allosteric effector in the mode of action of phosphofructokinase?
|
High levels of ATP depress the rate of the reaction, and low levels of ATP stimulate the reaction.
|
|
At what point in glycolysis are all the reactions considered doubled?
|
After aldolase splits fructose-1,6-bisphospate into dihydroxyacetone p and glyceraldehyde-3-P.
|
|
What enzymes are NADH-linked dehydrogenases?
|
glyceraldehyde-3-phosphate dehydrogenase
|
|
What is a substrate level phosphorylation?
|
A rxn in which the source of phosphorous is inorganic phosphate ion, not ATP.
|
|
What rxns are the control points in glycolysis?
|
Reactants catalyzed by:
(1) hexokinase (2) Phosphofructokinase (3) Pyruvate kinase |
|
What is a negative regulator of hexokinase?
|
Glucose-6-p
|
|
What is a negative regulator of phosphofructokinase?
|
(1) ATP
(2) citrate (3) phosphoenolypyruvate |
|
What is a positive regulator of phosphofructokinase?
|
(1) AMP
(2) fructose-2,6-bisphospate |
|
What is a negative regulator of pyruvate kinase?
|
(1) ATP
(2) acetyl CoA (3) alanine |
|
What is a positive regulator of pyruvate kinase?
|
(1) fructose-1,6-bisphosphate
(2) AMP |
|
Which part of glyceraldehyde-3-P dehydrogenase would be the most conserved between other enzymes?
|
The binding site.
|
|
What rxn type is catalyzed by a kinase?
|
A phosphate-tranfer enzyme with ATP as the usual source of phosphate.
|
|
What rxn type is catalyzed by a isomerase?
|
Changing the form of the molecule.
|
|
What rxn type is catalyzed by a aldolase?
|
Performing an aldl cleavge of a sugar to yield two smaller sugars or sugar derivatives.
|
|
What rxn type is catalyzed by a dehydrogenase?
|
Changing the oxidation state of a substrate by removing hydrogens while simultaneously changing the oxidation state of a coenzyme (NADH, FAD, etc.)
|