Gene Yang

CRISPR was and how it was being used in recent times to engineer everything around us by small steps. Before my research findings I had an idea what CRISPR was such as how it was being used around the world on modifying genes, and engineering new species by deleting or replacing the genes that were unwanted by that organism. What I knew about CRISPR includes just main things such as how it works and basic genome sequences it would manipulate. I however did not know too much information about it…

moral issues with this topic. To begin what is a Designer Baby? According to the Oxford Living Dictionary a designer baby is, “a baby whose genetic makeup has been selected in order to eradicate a particular defect, or to ensure that a particular gene is present.” In other words this means that certain traits are selected for the baby. Then their implanted back into the embryo to create the “perfect child.” This technology may seem vary Sci Fi like, but in fact we have the capabilities of doing…

Nowadays you go online and you're able to customize your own clothing or shoes but what if I told you can do the same thing with you first child. After reading that sentence you’re probably thinking how is that even possible, did I read that right? It may seem absolutely mind blowing but it’s possible, scientists have found a way to genetically modify fetuses. However just because this process is possible doesn’t mean everyone is okay with it. In fact in most countries it’s illegal to go through…

A Panaroma of Primary Autosomal Recessive Microcephaly (MCPH) and the Role of Proteins contributing to its pathophysiology. Manal Alamery Ph.D, Atia Sheereen Ph.D. Abstract The underlying genetic etiologies of primary autosomal recessive microcephaly (MCPH) is complex and multifactorial. It's a primary disorder of neurogenic mitosis and is clinically reflected as small head size with varying mild intellectual disability. MCPH is a heterogeneous disorder, where…

JNK is one of the three branches of MAPK superfamily of serine/threonine protein kinases. Other members of this superfamily are p38 kinases and the ERKs (Kyriakis and Avruch, 2012). In mammals, there are 3 JNK genes: Jnk1, Jnk2, and Jnk3 on 3 different chromosomes, and each mammalian JNK gene has alternative splicing forms (Derijard et al., 1994). JNK is involved in many physiological and pathological processes. The JNK pathway plays a major role in apoptosis. JNK pathway is required for…

BENEFITS? These humanized mouse models involved a cecal ligation and puncture procedure to induce sepsis. Peripheral blood was collected from the mice at endpoint. This blood was used to analyse their gene expression, and thus determine which mouse model most closely resembles human sepsis according to gene expression…

and yang, heaven and earth, etc.), coexist together in order for the Way to be followed. Chapter one of the text begins by mentioning two different terms- "these two come forth in unity but diverge in name, their unity is known as an enigma." Already, a comparison is recognized in order to show how they work to a form a better union together. People may see two different ideas to be followed separately, but based on the text, but their combination is more advantageous to the Way.…

Most people know about the ancient Chinese belief of yin and yang. It represents the balance of good and evil in the world. However, yin and yang also represents a person - no one is completely good or evil. Squeaky, the dynamic protagonist of “Raymond’s Run” by Toni Cade Bambara, is a perfect example of this. She has many problems in her life: taking care of her mentally disabled brother, Raymond, and not living up to her mother’s expectation of being the typical girly girl. This makes her…

The study conducted by Yang et al. shows that CHIP regulates the level of katanin-p60 protein, which is required for the proper axonal growth in early developmental stages. CHIP antagonizes the effects of a deubiquitylating enzyme, USP47 by ubiquitinating and destabilizing katanin-p60 and hence presents an important role in axonal growth (Yang et al., 2013). Another study showed abnormal motor disturbances with altered phenotypic and…

Chapter 5 Dispute: Humans and Sharks both have four gill arches as embryos, but the germ layers and arches develop into unrelated structure in each organism My Dispute Statement: Both sharks and humans develop gill arches when enveloped in the embryo, with the arches creating very similar structures and functions in both. In humans during conception, 4 swellings appear on the throat area. These swellings called arches develop to create many of the structures and functions inside the head.…