the organelle is not severe. Specifically, when mitochondrial damage is not severe, the cellular functions could be impacted by ATP depletion. The latter can subvert activity of Na+/K+-ATPase (necessary for fluid pump activity) and integrity of the actin cytoskeleton (**) leading to compromised fluid pump and barrier functions, respectively. Thus, the goal of this experiment is to determine if the functional activity of mitochondria is in anyway compromised in…
divide and the two daughter cells appear. In Animals, the cytokinesis processes occurs through cleavage. Firstly, in the old metaphase plate position, a cleavage furrow is formed. On each sides of the furrow, a contractile ring formed of actin microfilaments. These actin microfilaments interact with myosin protein, which causes the contraction of the ring. This contraction is acting on pulling the rings so the furrow goes deeply until separating the cell into two cells. In plants, cytokinesis…
The sliding filament theory is how muscles are able to create force when having the thick (myosin) filaments slide past the thin (actin) filaments during muscle contraction overlapping in ratchet-like manner, this causes the sarcomere to contract, while staying at the same length. Nerve impulse causes the release of Ca+2 enabling the myosin bridges to bind with actin. 2. The proprioceptor system plays an indispensable role in bodily movement because what causes the amount that a muscle contracts…
flexors, back extensors, hamstrings and abdominal muscles in hyperlordotic postures (Diagram 2). Abdominal muscles are maintained in lengthened position and this will lead to a reduction of force that can be generated secondary to the contact between actin and myosin filaments reduce when the sarcomere is stretched (Rassier et al., 1999). Conversely, hip and back extensors will be shortened. Tight hip flexors and back extensors encourage pelvic innominate inclination at the operated side…
'filaggrin' was used to describe the whole class of proteins that had been found in a stratum corneum. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721001/) Filaggrin tends to associate with keratins, which take part in a formation of a scaffold. However, actin filaments or microtubules are not associated to filaggrin molecules. The synthesis of filaggrin begins with a large, insoluble precursor molecule, called profilaggrin, which can be found in stratum granulosum. During the cell maturation,…
promotes binding of Ca2+ to calmodulin, increasing the Ca2+/calmodulin concentration which is essential in activating myosin light chain kinase (MLCK). MLCK then phosphorylates myosin light chain (MLC), leading to the formation of cross-bridge between actin and myosin, thus…
Comparing with other disabilities, diseases, spinal cord injury is a critical disorder in worldwide. Physiology and anatomy The spinal cord(SC) is a grayish-white structure that begins superiorly at the foramen magnum in the skull, where it is continuous with the medulla obolongata of the brain. It terminates at the level of the lower border of the first lumbar vertebra. The spinal cord is located within the vertebral canal of the vertebral column, which is surrounded by three meninges: the…
Mary Warren is an important character in The Crucible by Authur Miller. However, Mary has very little power. She is a lower class servant who is bossed around by John Proctor. Yet when Mary is chosen to be a court official, she gets a little taste of power and suddenly develops a backbone. Over the course of the play, Mary Warren changes from an innocent and weak will girl to someone who is very bold and is not afraid to say what she feels. In the beginning of the play . Mary is characterized…
we come to we'll hire a hall and do the sword fight in Richard III. and the balcony scene in Romeo and Juliet. How does that strike you?" "I'm in, up to the hub, for anything that will pay, Bilgewater; but, you see, I don't know nothing about play-actin', and hain't ever seen much of it. I was too small when pap used to have 'em at the palace. Do you reckon you can learn me?" "Easy!" "All right. I'm jist a-freezn' for something fresh, anyway. Le's commence right away." So the duke he told…
To Kill A Mockingbird It’s a sin to kill a mockingbird. It’s a sin to kill someone who only does good and doesn’t harm anybody. In Harper Lee’s To Kill a Mockingbird Arthur Radley, Tom Robinson and Scout are portrayed as mockingbirds. These people haven’t done anything to hurt anyone. They try to help and make things better. While other people try to “kill” them. In the novel To Kill a Mockingbird by Harper lee uses the symbol of the mockingbird to display to them that it’s a sin to kill…