Psoriasis, Lichen Planus And Atopic Dermatitis

Front 1

_____________ is a chronic relapsing skin disease that can occur at any age. It is characterized by sharply demarcated lesions with clear cut borders, noncoherent silvery scales and a positive Auspitz sign.

Back 1

Psoriasis

Front 2

A positive sign is when:

Back 2

A blood droplet forms when you scratch off a scale.

Front 3

Psoriasis has a preference for _____________surfaces and _____________. They also tend to be _____________ and _____________.

Back 3

Extensor, buttocks, bilateral, symmetrical

Front 4

_____________ is the sudden appearance of numerous monomorphic psoriasis papules on the trunk and is often triggered by _____________ infection, particularly in adolescents and young adults without history of psoriasis.

Back 4

Guttate psoriasis, streptococcal.

Front 5

Guttate means _____________.

Back 5

Drop like

Front 6

Larger, chronic psoriasis plaques respond well to _____________therapy.

Back 6

UV light

Front 7

Painless separation of the nail from the nail bed that is associated with psoriasis.

Back 7

Onycholysis

Front 8

_____________ is the most characteristic sign of psoriasis on the nail plate.

Back 8

PItting

Front 9

Psoriatic lesions may develop after skin trauma, an effect called the____________.

Back 9

Koebner phenomenon

Front 10

_____________psoriasis is the least common form, but can be severe and require hospitalization.

Back 10

Erythrodermic

Front 11

Eryrthrodermic psoriasis is characterized by extensive _____________ and skin _____________ with itching and pain that can also affect _____________ control and _____________.

Back 11

Erythema, exfoliation, body temperature, heart rate

Front 12

__ to __% of psoriasis patients develop psoriatic arthritis, which is considered to be one of the sero-negative spondyloarthropathies. This anomaly is usually preceded by _____________ of psoriasis.

Back 12

5-20%, many years

Front 13

The skin changes in psoriasis stem from the increased rate of proliferation and shedding of _____________

Back 13

Keratinocytes

Front 14

Psoriasis is a _____________ mediated process in which CD4+ cells stimulate _____________ proliferation.

Back 14

T-Cell, keratinocyte

Front 15

_____________ and _____________ of psoriasis are typical over a lifetime.

Back 15

Exacerbations and remissions

Front 16

Topical treatments for psoriasis include _____________, creams, _____________, _____________ and _____________ light.

Back 16

Tar, steroids, cacipotriene, ultraviolet

Front 17

PUVA is _____________ + _____________, and is a treatment for _____________.

Back 17

Psoralens + UV, psoriasis

Front 18

Oral drugs for psoriasis include _____________, _____________, _____________ and _____________

Back 18

Retinoids, methotrexate, cyclosporin, steroids

Front 19

An uncommon, inflammatory papulosquamous disorder of unknown etiology.

Back 19

Lichen planus

Front 20

_____________, _____________, _____________ and _____________ (especially the oral mucosa) may be affected by lichen planus.

Back 20

Skin, nails, hair, mucous membranes

Front 21

Itching involved with lichen planus is usually _____________, most often intermittent, and _____________

Back 21

Variable, insatiable

Front 22

Lichen planus can occur _____________ as generalized disease, and may be secondary to a _____________.

Back 22

Abruptly, drug.

Front 23

In rare cases, oral lichen planus may degenerate into _____________.

Back 23

Squamous cell carcinoma

Front 24

White, violaceous, hyperkeratotic plaque with a white, lacelike pattern on the surface is known as _____________ and is associated with _____________.

Back 24

Wickham striae, lichen planus

Front 25

In oral lichen planus, lacy white plaques called _____________ are present on the _____________, and are usually bilateral and _____________.

Back 25

Wickham's striae, buccal mucosa, symmetrical

Front 26

Lichen planus prefers the _____________ surfaces of the wrists, forearms, ankles, abdomen and sacrum.

Back 26

Flexor

Front 27

What are the five P's of lichen planus?

Back 27

Pruritic, planar, polygonal, purple (violaceous), papules/plaques

Front 28

Lichen planus is a _____________ disease that usually resolves within __ to __ months.

Back 28

Self limited, 8-12

Front 29

The first line of treatment for lichen planus is _____________.

Back 29

Topical steroids`

Front 30

This is a common, chronic inflammatory papulosquamous disease with unknown etiology. It is characterized by yellow, greasy and scaling papules with coalescing red patches and plaques.

Back 30

Seborrheic dermatitis

Front 31

Seborrheic dermatitis favors areas where the _____________ of _____________ is maximal, such as the scalp margins, central face and presternal areas.

Back 31

Concentration of sebaceous

Front 32

Characteristic locations of seborrheic dermatitis are the _____________, base of the _____________, _____________ folds and _____________ skin, and external _____________ canals.

Back 32

eyebrows, eyelashes, nasolabial, paranasal, ear

Front 33

Scale adherent to the eyelashes and lid margins with variable amounts of erythema is characteristic of _____________.

Back 33

Seborrheic dermatitis.

Front 34

Seborrheic dermatitis has been linked to _____________ yeast in adolescents and adults.

Back 34

Pityrosporum (Malassezia)

Front 35

Seborrhea in infants is usually a _____________ condition that rarely requires treatment. If it must be treated, it can be with _____________ and a soft _____________. Low strength _____________ may be needed for resistant cases

Back 35

Self-limiting, oil, brush, corticosteroid

Front 36

Infantile _____________ and _____________ often occur simultaneously, which can be confusing when deciding on a treatment.

Back 36

Seborrhea, atopic dermatitis

Front 37

A method of distinguishing between seborrheic dermatitis and psoriasis is that SD prefers _____________ surfaces while psoriasis prefers _____________ surfaces of the extremities.

Back 37

Flexor, extensor

Front 38

SD lacks the characteristic vivid red hue or _____________ scale of psoriasis, which is generally more _____________ or _____________ colored.

Back 38

micaceous, pink, salmon

Front 39

Seborrheic dermatitis is treated with topical _____________, antidandruff shampoo or soaps containing _____________ (ZNP), selenium sulfide, _____________, coal tar, salicylic acid and tea tree oils.

Back 39

antifungals, zinc pyrithione, ketoconoazole

Front 40

Poorly defined, erythematous patches, papules and plaques with or without a scale in which the skin appears edematous. Erosions are moist, crusted, linear or punctuate, resulting from scratching. Skin may be extremely _____________, _____________ and _____________.

Back 40

Acute atopic dermatitis, dry, cracked, scaly.

Front 41

Lichenification resulting from repeated rubbing or scratching; follicular lichenification (especially in darkly pigmented persons).

Back 41

Chronic atopic dermatitis.

Front 42

_____________ atopic dermatitis is characterized by _____________, which are painful, especially in flexures, on palms, fingers and soles.

Back 42

Chronic, fissures

Front 43

Thickening and hardening of the skin, often resulting from the irritation caused by repeated scratching of a pruritic lesion.

Back 43

Lichenification

Front 44

Atopic dermatitis usually begins in _____________, before the age of _____________ years.

Back 44

Infancy, 5

Front 45

Atopic dermatitis is characterized by _____________ skin and _____________; consequent rubbing leads to increased inflammation and _____________ and to further itching and scratching. This is known as the _____________ cycle.

Back 45

Dry, Pruritis, lichenification, itch-scratch

Front 46

Atopic dermatitis is believed to be the result of a _____________ dysfunction and _____________ reactivity.

Back 46

skin barrier, IgE

Front 47

Atopic dermatitis has a strong/weak genetic basis.

Back 47

Strong

Front 48

Atopic dermatitis can be exacerbated by _____________ disruption, which is a decrease of barrier function and increased transepidermal _____________. The patient must limit bathing and hand washing, as _____________ is an exacerbating factor.

Back 48

Skin barrier, water loss, dehydration

Front 49

_____________ and _____________ are two organisms that can exacerbate atopic dermatitis.

Back 49

S. aureus, group A strep

Front 50

Atopic dermatitis in children presents as papular, lichenified plaques, erosions and crusts on the _____________ and _____________ fossae, the _____________ and the _____________.

Back 50

Antecubital, popliteal, neck, face

Front 51

_____________ and _____________ are the most conspicuous symptoms of atopic dermatitis on adults.

Back 51

Lichenification and excoriations

Front 52

Management of atopic dermatitis include _____________ skin care with _____________ and topical _____________, _____________ therapy and _____________ as sedatives.

Back 52

Optimal, hydration, moisturizers, wet-wrap, antihistamines

Front 53

Pathogenesis of _____________ is activated CD4+ T cells that produce inflammatory cytokines, resulting in keratinocyte hyperproliferation.

Back 53

Psoriasis

Front 54

Pathogenesis of _____________ is activated CD8+ T cells that kill keratinocytes and release inflammatory cytokines.

Back 54

Lichen planus

Front 55

Pathogenesis of _____________ is immune/inflammatory response to Malassesia, resulting in complement activation.

Back 55

Seborrheic dermatitis

Front 56

Pathogenesis of _____________ is an impaired skin barrier; related to IgE mediated diseases.

Back 56

Atopic dermatitis