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91 Cards in this Set
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Surgery for bicornuate uterus |
Strassman Sx
After Sx if she conceives then LSCS at 38 weeks & now recently hysteroscopic metroplasty |
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Mayor rokitansky kuster hauser syndrome |
Mullerian agenesis Vaginal atresia Uterine atresia |
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Vaginal agenesis Sx |
Done when the girl is about to get married or just married Mc indoe operation Williams vaginoplasty (pouch out if labio majora) Amniovaginoplasty |
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Transverse vaginal septum |
Causes imperforate vagina (vaginal agenesis) MC located at upper part (external os) |
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MC uterine malformation associated with infertility |
Septate anomaly |
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IOC for uterine anomalies |
3D USG MRI Sono hysterography HSG leads to false positivity |
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Multiple luteal cysts in ovary |
Pregnancy Multiple pregnancy HCG therapy Hydatidiform mole Choriocarcinoma |
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Pain in endometriosis |
Related to depth of invasion (>5mm)
Infertility is related to superficial invasion CA125 for recurrence |
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CA125 |
Cut off normal levels <35 mIU/L Raised in Endometriosis TB Ovarian Ca Borderline ovarian tumors
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Allen masters syndrome |
Defects in Peritoneum Scarring overlying implants |
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Diagnosis of endometriosis |
Laparoscopy Powder burn/gun shot lesions with fibrosis surrounding Pseudoxanthoma cells (macrophages with hemosiderin) |
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Mittelschmerz |
Painful ovulation (sharp pain in lower abdomen) Associated with rupture of ovarian follicle |
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Administration of SSRI's in PMS |
Luteal phase |
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Rotterdam criteria |
Ovulatory dysfunction (oligomenorrhea or hyperandrogenism)
Clinical or biochemical evidence of hyperandrogenism
USG criteria Any 2 among 3 |
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Sampling of LH &FSH in PCOS |
1 to 4 days of the cycle |
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Testosterone levels in women |
Free testosterone >200ng/dl (ovarian lesion) DHEA >700mcg/dl (adrenal lesion) |
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Associations of PCOS |
Hirsutism Endometrial ca Insulin resistance |
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Guinagolide |
Newer dopamine agonist fir hyperprolactinemia Non ergot D2 dopamine agonist |
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Diagnosis of ca cervix |
Pap smear for screening Punch biopsy -> colposcopy & biopsy -> cone biopsy |
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MC cause of death in ca cervix |
Renal failure (uremia) due to obstruction of ureters 2nd most common cause is hemorrhage |
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Microinvasive carcinoma |
Stromal invasion <5mm Lateral spread <7mm
Rx simple hysterectomy |
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HPV triage |
Colposcopy Liquid based cytology Hybrid capture 2 for HPV DNA |
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Indications of trachelectomy |
Preservation of fertility Early stage disease (1A1 1A2 1B1) Small tumor volume <2 cms No pelvic node metastasis Cancer margin 1 cm below the internal os on MRI |
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D/D for verrucous carcinoma |
Condylomata acuminata (hpv6,11) Verrucous carcinoma is a scc variant of cervix |
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MC site of vulval cancer |
Labia majora > clitoris > labia minora SCC is commonest vulval ca followed by melanoma (clitoris > labia minora) |
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Best method of prevention of ca ovary |
Prophylactic hysterectomy + BSO 2nd line - screening + ocp's Screening - TVS + CA125 done every 6 to 12 months after 35 years and MRI or mammo for breast cancer |
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Female equivalent of Seminoma |
Dysgerminoma |
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Largest benign ovarian tumor |
Mucinous cyst adenoma |
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Ovarian tumor associated with lymphocytic infiltration |
Dysgerminoma |
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Mucinous tumor associated with dermoid cyst |
Brenners tumor |
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Masculizing tumors of ovary |
Arrhenoblastoma
Adrenal cortical tumor/lipoid cell tumor of ovary
Hilus cell tumor
Gynandroblastoma (granulosa + arrhenoblastoma) |
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MC used chemo regimens in dysgerminoma |
Unilateral oophorectomy Or Partial resection of the tumor BEP - Bleomycin, Etoposide, cisPlatin (best result with 4 cycles)
VBP - vinblastin, Bleomycin, cisPlatin
VAC - Vincristine, Actinomycin, cyclophosphamide |
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Meigh & pseudo meigh |
Meigh (fibroma) Tumor must be ovarian, solid & benign
Hydrothorax, ascites present
Removal of tumor result in spontaneous resolution
Psuedomeigh Brenner & granulosa tumor
Hydrothorax could be a pulmonary manifestation
Exudate is through electrolyte imbalance unlike due to ovarian tumor in meigh |
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Risk of malignancy score |
Ultrasound sound score × menopausal score × CA 125 levels in U/ml >200 have a high ovarian carcinoma risk |
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Pelvic calcifications |
Fibroids - popcorn calcification Dermoid cyst - commonest ovarian mass to calcify Other ovarian masses - cystadenoma/carcinoma/fibroma Pseudomyxomaperitonei Fallopian tube calcification - TB Uterine - endometrial calcification from chronic endometritis |
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Investigation for ovarian tumor |
CA125 PET is preferred over CT as PET differentiate between relapsed tumor & fibrosis |
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Staging of ovarian cancer |
Peritoneal washing Peritoneal biopsy Palpation of organs |
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Management of endometrial hyperplasia |
Non atypical hyperplasia Progesterone Simple atypical hyperplasia not preferring pregnancy Simple hysterectomy Preferring pregnancy Counseling & high dose Progesterone Complex hyperplasia without atypia Progesterone Follow up Simple hyperplasia without atypia Follow up without therapy
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Malignancies with long term Tamoxifen |
Endometrial ca Uterine sarcoma Rarely liver ca Non malignant Endometrial hyperplasia Endometriosis Fibroid uterus Ovarian cyst Amenorrhea |
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Diagnosis of endometrial ca |
Fractional curettage > hysteroscopy and biopsy used for cervical stenosis patients (but advanced than fraction) TVS |
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Mixed mullerian carcinogenesis |
Carcinomatous & sarcomatous changes Heterologous (extra uterine tissue) Homologous (smooth muscle differentiation) Post menopausal women Rx Sx followed by chemo |
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MC sites of injury causing UV fistula |
Where ureter crosses below uterine arteries 2nd most common Behind the infundibulo pelvic ligament at the pelvic brim |
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Prolapse order |
Anterior wall prolapse (Cystocele) > posterior wall prolapse > uterine prolapse |
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Congenital prolapse |
Seen in young nulliparous women Risk factors Spina bifida Marfans Ehler danlos Management Purandare sling Shirodkar sling Virkud's Sling made of mersilene tape |
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Surgeries for ureteric fistula |
Bladder flap procedure (modified boari ocker blad)
Ureteroneocystostomy
Implantation into the bladder Colonic transplantation leads to recurrent pyelonephritis, hyperchloremic acidosis |
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Lead pipe appearance |
Fallopian tube in TB |
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Syndromic management of STD's |
Metronidazole Fluconazole |
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Qualitative & quantitative tests for fetomaternal hemorrhage |
Apt Singles alkaline denaturation test & Kleihuer betke test Citric acid elution test Respectively |
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General anaesthetia in pregnancy |
IAP Intra cardiac shunts Aortic stenosis Pulm HTN |
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Bispinous diameter |
10 centimeters |
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Layers of uterus |
Endo Stratum functionalis Stratum basale Myo Outer longitudinal Criss cross Inner circular Peri |
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Uterus relations at cornua |
Ant - round ligament tube Post - ovarian ligament |
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Level of anaesthesia's |
Epidural - T10 LSCS - T4 Nerve supply T10 to L1 |
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Layers of cervix |
Ecto - stratified squamous Endo - columbar Transition - metaplasia Length is 2.5 cms in non pregnant and 4 cms in pregnant |
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B supply to cervix |
Descending cervical artery |
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Lymphatic drainage of cervix |
I (H) OPE Internal & external iliac Obturator Paracervical (sentinel) Parametrial |
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Narrowest parts of fallopian tube |
Intra mural 1.25 cms (anatomical sphincter) (last to rupture)
Later isthmus 2.5 cms |
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Venous drainage of ovaries |
Left ovarian vein into left renal vein Right ovarian vein into IVC |
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Cervix and all fornices related to |
Uterine vessels Mackendrot ligament Ureter |
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Lateral relations of vagina |
Mackendrots ligament or pelvic cellular tissue Levator ani muscle Bulbus cavernosus Vestibular bulb Bartholin glands |
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Hysterectomy with highest risk of ureteric injury |
Wertheims hysterectomy |
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Epithelial cells of vagina |
Parabasal/basal - before puberty or menopausal Intermediate - progesterone Superficial - estrogen |
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P/I/S |
Postmenopausal - 100/0/0 Pre ovulatory - 0/40/60 Secretory - 0/70/30 |
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Lymphatic drainage of vagina |
Upper 3rd - ext & int iliac Middle 3rd - int iliac Lower 3rd - sup inguinal |
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Feedbacks in HPO axis |
+ve - leptin, glutamate, kisspeptide -ve - GABA, neuropeptide Y |
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Investigations of polyp |
USG - feeding vessel sign
Best is saline infusion sonhysteroscopy Rx - hysteroscopic D & C |
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Investigations of adenomyosis |
USG MRI is gold standard |
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FIGO classification of AUB |
PALM (anatomical) COEIN (functional) P - polyp A - adenomyosis L - leiomyoma M - malignancy & hyperplasia C - coagulopathy O - ovulatory dysfunction E - endometrial I - iatrogenic N - not specified |
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Endometrial assessment and biopsy |
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Genes for growth of testis |
Sry gene on short arm of Y "SOX 9 gene" |
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Genes for development of ovaries |
WNT4 gene RSPO1 gene |
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Para ovarian cyst |
Block in paraphoron cyst |
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DES exposure in utero |
T shaped uterus Vaginal adenocarcinoma |
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Investigations of uterine anomalies |
IOC - 3D USG/MRI
Gold standard - hysteroscopy & laparoscopy |
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Indication for surgery in bicornuate uterus |
Habitual abortions |
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Surgeries of uterine anomalies |
Bicornuate/didelphys - Jones metroplasty Strassman metroplasty (mc) Septate - hysteroscopic transcervical septal resection |
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Reifeinstein syndrome |
Partial AIS Scanty pubic & axillary hair |
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Rx of AIS |
Vaginoplasty just before marriage by - frank dilator, mcindoe or williams vulvovaginoplasty Gonadectomy performed after SSC developed and estrogen is taken for lifelong |
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Main causes of primary amenorrhea |
Genetic > MRKH > AIS |
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Kallman syndrome |
Hypogonadotropic hypogonadism Anosmia Anemia Absence of GnRH Normal height |
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Secondary amenorrhea |
Mc physiological - pregnancy Mc pathological - PCOS |
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Asherman |
Uterine synechia Honeycomb appearance in HSG (IOC) Hysteroscopy (gold standard) Mx - hysteroscopic adhesiolysis Cu T |
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Savage syndrome |
FSH receptor mutation FSH > 40 IU/L E2 normal Increase antral follicules |
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Diagnosis of prolactinoma |
>30 ng/ml - take serum TSH >100ng/ml - MRI |
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Failure of lactation post delivery |
Sheehan syndrome |
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Earliest sign of pregnancy |
Subnuclear basal vacuolization As early as 36 hr post ovulation |
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Best test for ovarian reserve |
Serum amh <1mIU/L in poor ovarian reserve Also serum inhibin B |
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Hyperstimulation syndrome |
Release of cytokines and inflammatory mediators -> VEGF -> damage to vessel wall -> third space loss |
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Gold standard investigation for tubal factors |
Laparoscopic chromopertubation |
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Tubal recanalization |
Reversal best with Clips > falope rings > modified pomeroy > cautery Lenght >4 cms Isthmoisthmic anastomosis Age <35 years |
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Sims cohner test |
Post coital test |