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91 Cards in this Set

  • Front
  • Back

Surgery for bicornuate uterus

Strassman Sx



After Sx if she conceives then LSCS at 38 weeks & now recently hysteroscopic metroplasty

Mayor rokitansky kuster hauser syndrome

Mullerian agenesis



Vaginal atresia


Uterine atresia

Vaginal agenesis Sx

Done when the girl is about to get married or just married



Mc indoe operation



Williams vaginoplasty (pouch out if labio majora)



Amniovaginoplasty

Transverse vaginal septum

Causes imperforate vagina (vaginal agenesis)



MC located at upper part


(external os)

MC uterine malformation associated with infertility

Septate anomaly

IOC for uterine anomalies

3D USG


MRI


Sono hysterography



HSG leads to false positivity

Multiple luteal cysts in ovary

Pregnancy


Multiple pregnancy


HCG therapy


Hydatidiform mole


Choriocarcinoma


Pain in endometriosis

Related to depth of invasion (>5mm)



Infertility is related to superficial invasion



CA125 for recurrence

CA125

Cut off normal levels <35 mIU/L



Raised in



Endometriosis


TB


Ovarian Ca


Borderline ovarian tumors




Allen masters syndrome

Defects in Peritoneum



Scarring overlying implants

Diagnosis of endometriosis

Laparoscopy



Powder burn/gun shot lesions with fibrosis surrounding



Pseudoxanthoma cells (macrophages with hemosiderin)



Mittelschmerz

Painful ovulation (sharp pain in lower abdomen)



Associated with rupture of ovarian follicle


Administration of SSRI's in PMS

Luteal phase

Rotterdam criteria

Ovulatory dysfunction (oligomenorrhea or hyperandrogenism)



Clinical or biochemical evidence of hyperandrogenism



USG criteria



Any 2 among 3

Sampling of LH &FSH in PCOS

1 to 4 days of the cycle

Testosterone levels in women

Free testosterone >200ng/dl (ovarian lesion)



DHEA >700mcg/dl (adrenal lesion)

Associations of PCOS

Hirsutism


Endometrial ca


Insulin resistance

Guinagolide

Newer dopamine agonist fir hyperprolactinemia



Non ergot D2 dopamine agonist

Diagnosis of ca cervix

Pap smear for screening



Punch biopsy -> colposcopy & biopsy -> cone biopsy

MC cause of death in ca cervix

Renal failure (uremia) due to obstruction of ureters



2nd most common cause is hemorrhage

Microinvasive carcinoma

Stromal invasion <5mm


Lateral spread <7mm



Rx simple hysterectomy

HPV triage

Colposcopy


Liquid based cytology


Hybrid capture 2 for HPV DNA

Indications of trachelectomy

Preservation of fertility



Early stage disease (1A1 1A2 1B1)



Small tumor volume <2 cms



No pelvic node metastasis



Cancer margin 1 cm below the internal os on MRI


D/D for verrucous carcinoma

Condylomata acuminata (hpv6,11)



Verrucous carcinoma is a scc variant of cervix



MC site of vulval cancer

Labia majora > clitoris > labia minora



SCC is commonest vulval ca followed by melanoma (clitoris > labia minora)

Best method of prevention of ca ovary

Prophylactic hysterectomy + BSO



2nd line - screening + ocp's


Screening - TVS + CA125 done every 6 to 12 months after 35 years and MRI or mammo for breast cancer



Female equivalent of Seminoma

Dysgerminoma

Largest benign ovarian tumor

Mucinous cyst adenoma

Ovarian tumor associated with lymphocytic infiltration

Dysgerminoma

Mucinous tumor associated with dermoid cyst

Brenners tumor

Masculizing tumors of ovary

Arrhenoblastoma



Adrenal cortical tumor/lipoid cell tumor of ovary



Hilus cell tumor



Gynandroblastoma (granulosa + arrhenoblastoma)

MC used chemo regimens in dysgerminoma

Unilateral oophorectomy


Or


Partial resection of the tumor



BEP - Bleomycin, Etoposide, cisPlatin (best result with 4 cycles)



VBP - vinblastin, Bleomycin, cisPlatin



VAC - Vincristine, Actinomycin, cyclophosphamide

Meigh & pseudo meigh

Meigh (fibroma)


Tumor must be ovarian, solid & benign



Hydrothorax, ascites present



Removal of tumor result in spontaneous resolution



Psuedomeigh


Brenner & granulosa tumor



Hydrothorax could be a pulmonary manifestation



Exudate is through electrolyte imbalance unlike due to ovarian tumor in meigh

Risk of malignancy score

Ultrasound sound score × menopausal score × CA 125 levels in U/ml



>200 have a high ovarian carcinoma risk

Pelvic calcifications

Fibroids - popcorn calcification



Dermoid cyst - commonest ovarian mass to calcify



Other ovarian masses - cystadenoma/carcinoma/fibroma



Pseudomyxomaperitonei



Fallopian tube calcification - TB



Uterine - endometrial calcification from chronic endometritis

Investigation for ovarian tumor

CA125



PET is preferred over CT as PET differentiate between relapsed tumor & fibrosis

Staging of ovarian cancer

Peritoneal washing


Peritoneal biopsy


Palpation of organs

Management of endometrial hyperplasia

Non atypical hyperplasia


Progesterone



Simple atypical hyperplasia not preferring pregnancy


Simple hysterectomy



Preferring pregnancy


Counseling & high dose Progesterone



Complex hyperplasia without atypia


Progesterone


Follow up



Simple hyperplasia without atypia


Follow up without therapy


Malignancies with long term Tamoxifen

Endometrial ca


Uterine sarcoma


Rarely liver ca



Non malignant


Endometrial hyperplasia


Endometriosis


Fibroid uterus


Ovarian cyst


Amenorrhea

Diagnosis of endometrial ca

Fractional curettage > hysteroscopy and biopsy used for cervical stenosis patients (but advanced than fraction)



TVS

Mixed mullerian carcinogenesis

Carcinomatous & sarcomatous changes



Heterologous (extra uterine tissue)



Homologous (smooth muscle differentiation)



Post menopausal women



Rx


Sx followed by chemo

MC sites of injury causing UV fistula

Where ureter crosses below uterine arteries



2nd most common


Behind the infundibulo pelvic ligament at the pelvic brim

Prolapse order

Anterior wall prolapse (Cystocele) > posterior wall prolapse > uterine prolapse

Congenital prolapse

Seen in young nulliparous women



Risk factors


Spina bifida


Marfans


Ehler danlos



Management


Purandare sling


Shirodkar sling


Virkud's



Sling made of mersilene tape

Surgeries for ureteric fistula

Bladder flap procedure (modified boari ocker blad)



Ureteroneocystostomy



Implantation into the bladder



Colonic transplantation leads to recurrent pyelonephritis, hyperchloremic acidosis

Lead pipe appearance

Fallopian tube in TB

Syndromic management of STD's

Metronidazole


Fluconazole

Qualitative & quantitative tests for fetomaternal hemorrhage

Apt


Singles alkaline denaturation test


&


Kleihuer betke test


Citric acid elution test



Respectively

General anaesthetia in pregnancy

IAP



Intra cardiac shunts



Aortic stenosis



Pulm HTN

Bispinous diameter

10 centimeters

Layers of uterus

Endo



Stratum functionalis


Stratum basale





Myo


Outer longitudinal



Criss cross


Inner circular



Peri

Uterus relations at cornua

Ant - round ligament tube



Post - ovarian ligament

Level of anaesthesia's

Epidural - T10



LSCS - T4



Nerve supply T10 to L1

Layers of cervix

Ecto - stratified squamous



Endo - columbar



Transition - metaplasia



Length is 2.5 cms in non pregnant and 4 cms in pregnant

B supply to cervix

Descending cervical artery

Lymphatic drainage of cervix

I (H) OPE



Internal & external iliac



Obturator



Paracervical (sentinel)


Parametrial


Narrowest parts of fallopian tube

Intra mural 1.25 cms (anatomical sphincter) (last to rupture)



Later isthmus 2.5 cms

Venous drainage of ovaries

Left ovarian vein into left renal vein



Right ovarian vein into IVC

Cervix and all fornices related to

Uterine vessels


Mackendrot ligament


Ureter

Lateral relations of vagina

Mackendrots ligament or pelvic cellular tissue



Levator ani muscle



Bulbus cavernosus



Vestibular bulb



Bartholin glands

Hysterectomy with highest risk of ureteric injury

Wertheims hysterectomy

Epithelial cells of vagina

Parabasal/basal - before puberty or menopausal



Intermediate - progesterone



Superficial - estrogen

P/I/S

Postmenopausal - 100/0/0



Pre ovulatory - 0/40/60



Secretory - 0/70/30

Lymphatic drainage of vagina

Upper 3rd - ext & int iliac



Middle 3rd - int iliac



Lower 3rd - sup inguinal

Feedbacks in HPO axis

+ve - leptin, glutamate, kisspeptide



-ve - GABA, neuropeptide Y

Investigations of polyp

USG - feeding vessel sign



Best is saline infusion sonhysteroscopy



Rx - hysteroscopic D & C

Investigations of adenomyosis

USG



MRI is gold standard

FIGO classification of AUB

PALM (anatomical)


COEIN (functional)



P - polyp


A - adenomyosis


L - leiomyoma


M - malignancy & hyperplasia


C - coagulopathy


O - ovulatory dysfunction


E - endometrial


I - iatrogenic


N - not specified

Endometrial assessment and biopsy

Genes for growth of testis

Sry gene on short arm of Y



"SOX 9 gene"

Genes for development of ovaries

WNT4 gene


RSPO1 gene

Para ovarian cyst

Block in paraphoron cyst

DES exposure in utero

T shaped uterus



Vaginal adenocarcinoma

Investigations of uterine anomalies

IOC - 3D USG/MRI



Gold standard - hysteroscopy & laparoscopy

Indication for surgery in bicornuate uterus

Habitual abortions

Surgeries of uterine anomalies

Bicornuate/didelphys - Jones metroplasty


Strassman metroplasty (mc)



Septate - hysteroscopic transcervical septal resection

Reifeinstein syndrome

Partial AIS



Scanty pubic & axillary hair

Rx of AIS

Vaginoplasty just before marriage


by - frank dilator, mcindoe or williams vulvovaginoplasty



Gonadectomy performed after SSC developed and estrogen is taken for lifelong

Main causes of primary amenorrhea

Genetic > MRKH > AIS

Kallman syndrome

Hypogonadotropic hypogonadism



Anosmia


Anemia


Absence of GnRH


Normal height

Secondary amenorrhea

Mc physiological - pregnancy



Mc pathological - PCOS

Asherman

Uterine synechia



Honeycomb appearance in HSG (IOC)



Hysteroscopy (gold standard)



Mx - hysteroscopic adhesiolysis


Cu T

Savage syndrome

FSH receptor mutation



FSH > 40 IU/L


E2 normal


Increase antral follicules

Diagnosis of prolactinoma

>30 ng/ml - take serum TSH


>100ng/ml - MRI

Failure of lactation post delivery

Sheehan syndrome

Earliest sign of pregnancy

Subnuclear basal vacuolization


As early as 36 hr post ovulation

Best test for ovarian reserve

Serum amh <1mIU/L in poor ovarian reserve



Also serum inhibin B

Hyperstimulation syndrome

Release of cytokines and inflammatory mediators -> VEGF -> damage to vessel wall -> third space loss

Gold standard investigation for tubal factors

Laparoscopic chromopertubation

Tubal recanalization

Reversal best with


Clips > falope rings > modified pomeroy > cautery



Lenght >4 cms



Isthmoisthmic anastomosis



Age <35 years

Sims cohner test

Post coital test