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97 Cards in this Set

  • Front
  • Back

preterm, term, etc.

**bigger is better; delay deliveries until 39 weeks

**bigger is better; delay deliveries until 39 weeks

corrected age

**actual -- weeks of premature


correct for 2 years; most meaningful in first year of life

catch up

head circumference--


• early catch up in first few months post term unless ELBW



weight and length--


• catch up by 1st year if > 30 weeks


• catch up by 2nd year if < 30 weeks

contributing factors of prematurity

• advanced maternal age


• HTN; vasoconstriction >> placental insufficiency


• IUGR
• chromosomal abnormalities


• gestational DO


• chronic health DO


• assisted reproductive technologies


• multiple births


• c-sections

4 Us of late preterm & early term infants

1/ unrecognized as premature


• may not be transferred to NICU



2/ underestimated for morbidity & mortality


• 3x higher than term infants


• 19% risk of NICU admission



3/ unpredictable


• hypothermia


• hypoglycemia; short liver, (-) glycogen stores


• respiratory support



4/ understudied


Why do premies experience respiratory distress?

Surfactant is not produced until week 34

What labs are needed for premies from the nursery?

• blood type


• glucose screening


• bilirubin


• CBC


• coombs test


• rapid plasma reagin (RPR)

When should premies have their first well visit?

**within 48 hours of discharge


sooner if closer monitoring or further screening needed

first visit

• adaptation to home environment


• parental adjustment / bond


• reassurance


• review thorough history, i.e. NICU summary


• discuss plans of health care maintenance, immunizations, & referrals


• get to know infant

T/F. Mothers of premies have higher rates of maternal depression.

True; depressed moms are more likely to have an infant w/ poor growth & development >> perform edinburg postpartum depression scale

premie hospital readmissions

• 25-58%


• dehydration, respiratory, & feeding issues


• can continue to have higher rates during 2nd year of life

premie PE

throat--


• suck-swallow


• tongue trust


• oral aversion


• uvula movement


• gag reflex



respiratory--


• RR, retractions, stridor


• RSV patients wheeze



neck & shoulder--


• poor head control


• tight scarf sign


• difficulty bringing hands midline



trunk--


• arching


• (-) ROM


• hypotonia >> neuro f/u



extremities--


• hypo/hyper tone


• hyperreflexia


• clonus


• babinski

postural reflexes

landau--


• present by 5-6 mos


• lift & extend neck & trunk


 


parachute


• present by 6-8 mos


• look for symmetric response


 


propping reflex--


• anterior propping when sitting


• lateral propping...

landau--


• present by 5-6 mos


• lift & extend neck & trunk



parachute


• present by 6-8 mos


• look for symmetric response



propping reflex--


• anterior propping when sitting


• lateral propping to maintain balance

immunizations

**AAP recommends immunizations based on chronological age



• hep B after 2 kg


• palivizumab

palivizumab

**antibodies for preterm or at-risk infants for RSV



• 15 mg/kg monthly nov-april; 5 dose max


• continue during 2nd year of life IF on O2


• stop if breakthrough RSV occurs w/ hospitalization

premie weight gain

15-20 g daily

premie length

**1.1 cm per week until term


>> 0.75 cm for 3 mos


>> 0.5 cm during 3-6 mos

premie head circumference

**hydrocephaly if 1.25+ cm per week

**hydrocephaly if 1.25+ cm per week

nutritional needs

**137-165 cal/kg/day
chronic lung disease require higher calorie intake
 
premies have higher requirements due to--
• IUGR
• gut immaturity
• (+) BSA

**137-165 cal/kg/day


chronic lung disease require higher calorie intake



premies have higher requirements due to--


• IUGR


• gut immaturity


• (+) BSA

growth in VLBW infants

**take longer to catch up; most catch up by 2-3 years

**take longer to catch up; most catch up by 2-3 years

feeding problems

**parental support & education; teach how to pace child >> refer to specialist



• tonic bite reflex


• tongue thrust


• hyperactive gag reflex


• oral hypersensitivity from NGT/OGT


• microaspiration >> swallow study

How long does it take for a full term infant to transition to extrauterine life?

6-12 hours

full VS

heat loss

brown fat metabolism

**newborns generate heat by lipoysis of brown fat


brown fat storage begins @ 26-30 weeks



locations--


• scapula


• kidneys


• axilla


• neck

How do newborns respond to hyperthermia?

• (+) CO


• insensible water loss

consequences of heat loss

• hypoxia, apnea
• pulmonary HTN
• hypoglycemia
• metabolic acidosis
• (-) growth
 
>> can lead to death

• hypoxia, apnea


• pulmonary HTN


• hypoglycemia


• metabolic acidosis


• (-) growth



>> can lead to death

cold stress

**rectal temp < 36.5 °C = 97.6 °F


 


s&S--


• cool to touch


• central cyanosis


• poor feeding


• bradycardia


• apnea


• lethargy


• mottling

**rectal temp < 36.5 °C = 97.6 °F



s&S--


• cool to touch


• central cyanosis


• poor feeding


• bradycardia


• apnea


• lethargy


• mottling

T/F. Newborns cannot sweat/shiver in the first year of life.

True; tell parents to dress infant in one extra layer than what they would dress themselves

umbilical cord care

• dry it out >> falls within 7-10 days


• observe moisture & odor for infection; if streaking present >> intervene

penile care

**discuss risk & benefits of circumcision



circumcision care--


• petroleum jelly



uncircumcised penis--


• retract foreskin >> visualize meatus >> clean

sleeping pattern & positioning

• back to sleep; no side or stomach


• remove soft bedding, pillows, quilt, or stuffed animals >> suffocation

elimination patterns

**8-10 wet diapers


**soft, yellow stool



• meconium should be passed within first 24 hours


• breast milk babies have looser stool


• formula fed babies have darker and better-formed stool


• acholic stool- white, clay-like >> biliary issue >> GI consult

T/F. A pacifier may be used within the first few hours of life.

False; may start if established adequate breast feeding

T/F. Smoking is associated w/ SIDS.

True; assess infant's environment

T/F. A child's carseat should be switched to rear facing at 1 year or 20 pounds.

False; "1 and 20" are minimum requirements--not at time to switch


**carseat should be rear facing until 2 yrs

newborn screening

hearing--


• mandatory for all newborns before d/c


• if fail >> repeat


• if fail 2x >> refer



metabolic screening--


• heel stick evaluated for 30+ conditions


• guthrie spot must dry flat


• parents may refuse for religious beliefs; state dependent

metabolic screening timing

**PNP need to be able to educate, draw specimen @ correct times, & f/u appropriately



• risk of false (-) or false (+) hypothyroidism if < 12 hours >> screen before d/c @ 48-96 hours


• screen prior to transfusion


• sick or preterm infants should be screened @ birth, 48-72 hours, 28 days or d/c

cystic fibrosis (CF)

• meconium ileus


• intestinal obstruction

congenital hypothyroidism

• umbilical hernia


• jaundice


• enlarged fontanelle


• macroglossia

congenital heart defect screening

@ 24 hours of life; compare pulse ox of R hand & foot b/c unable to see cyanosis at 80-95%

@ 24 hours of life; compare pulse ox of R hand & foot b/c unable to see cyanosis at 80-95%

criteria for discharge

• gestation > 35 weeks


• VS stable


• cleared for d/c by HCP; provide name of new provider


• no abnormal cardiorespiratory findings


• no jaundice


• hearing, metabolic, & CHD screens


• cord clean & drying


• circumcision not bleeding


• suck/swallow coordination >> 2 successful feeds


• voided/stooled spontaneously once


• eye and vitamin K prophylaxis

attachment red flags

• no comfort seeking form caregiver


• no checking back w/ caregiver hen exploring


• no reaching out s/p brief separation

What should be done if hyperbilirubinemia is suspected?

1/ serum bilirubin


2/ transcutaneous bilirubin level if infant has no history & not severely jaundice

causes of hyperbilirubinemia

**based on mechanism of accumulation


• bilirubin overproduction


• (-) bilirubin conjugation, e.g. (-) albumin


• impaired bilirubin excretion

hyperbilirubinemia

**serum bilirubin > 5 mg/dL


• rate of rise is the most important thing


• 13+ mg/dL can result in minor neurological finding


• cephalocaudal progression; yellow sclera is late sign

pathologic jaundice

• within first 24 hours of life


• rises > 5 mg/dL/day


• > 17 mg/dL


• s&s of serious illness

estimated bilirubin levels

jaundice risk factors

hematological risk factors--


• ABO; mom is O, dad is A or B


• G6PD; enzyme deficiency in african, asian, & middle eastern



maternal risk factors--


• breastfeeding


• drugs, e.g. sulfa & strep


• gestational DM; (+) erythropoietin >> polycythemia



neonatal risk factors--


• birth trauma, e.g. cephalohematoma


• preterm & LBW infants


• TORCH, i.e. CMV, herpes, toxoplasmosis


• delayed passage of meconium >> unable to pass bilirubin


• polycythemia



other factors--


• males > females


• asians & american indians


• high altitudes, e.g. greece

physiologic jaundice

• 3-5 days of life >> declines over first week


• peaks @ 5-6 mg/dL; higher in asians @ 10 mg/dL

jaundice treatment

• no absolute level


• bhatani nomogram- based on hours & risk factors


• phototherapy- light changes structure in molecule >> cannot pass BBB


• exchange transfusion

Infants who present w/ severe jaundice that continues the past 1-2 weeks...

think--


• galactosemia


• congenital hypothyroidism


• results of newborn metabolic screen

jaundice PE

• hepatosplenomegaly


• petechiae


• microcephaly a/w hemolytic anemia, sepsis, congenital infection

jaundice differential diagnoses

• biliary atresia


• galactosemia


• breast milk jaundice


• hemolytic disease


• cholestasis


• hep B


• CMV


• hypothyroidism


• duodenal atresia


• dubin-johnson syndrome

Which infants need further evaluation?

• anemic @ birth


• ill appearing


• significant jaundice beyond first 2 weeks


• family history of jaundice requiring treatment or G6PD


• PE reveals findings not explained by physiologic hyperbilirubinemia

jaundice labs

• blood type


• direct coombs test for Rh incompatibility


• Hgb, Hct, serum albumin


• nomogram for hour specific bilirubin levels


• bilitool


• peripheral blood film for erythrocyte morphology


• conjugated bilirubin levels


• LFT; (+) SGOT/SGPT in hepatocellular disease


• viral & parasitic infection tests if HSM, petechiae, thrombocytopenia


• reducing substance in urine to screen for galactosemia


• ABGs; acidosis increases CNS toxicity risks


• thyroid function tests

jaundice diagnostic imaging

ultrasonography--


• indicated for signs of cholestatic disease



HIDA scan--


• indicated in biliary atreasia


• radionuclide liver scan for hepatoiminodiacetic acid uptake

early breastfeeding jaundice

• exaggerated physiologic jaundice


• caloric deprivation


• dehydration


• decreased volume


• delayed passage of meconium


• moderate jaundice @ 12 mg/dL

What is the treatment for early breastfeeding jaundice?

• (+) feeds


• supplement w/ formula if indicated


• no water or sugar water

late breastfeeding jaundice

• peaks @ 6-14 days; can persist for months


• 1/3 of all healthy breastfed infants


• non-pathological


• substances in maternal milk may inhibit normal bilirubin metabolism

What is the treatment for late breastfeeding jaundice?

>> temporarily interrupt breast feeding


>> formula supplementation


>> bilirubin decline over next 48 hours


>> confirms diagnosis


>> resume breastfeeding

phototherapy

**blue wavelength alters unconjugated bilirubin to less toxic, water soluble photoisomers >> excreted in bile & urine


• initiated based on age & TSB level from nomogram


• full term if >15 mg/dL


• older infant if >18 mg/dL

T/F. Phototherapy can be used in conjugated bilirubin.

False; bronze baby syndrome

exchange transfusion

• most rapid; reduces bilirubin by 50%


• prevents kernicterus


• removes partially hemolyzed & antibody coated erythrocytes >> replaces them w/ uncoated RBCs


• corrects anemia


• transfer to NICU for procedure

kernicterus

**yellow staining of basal ganglia



incidence increases w/ early discharge--


• lethargic @ home


• poor feeder


• irritable, hypotonic

desquamation

**dry newborn skin


• generalized superficial desquamation within first 24-48 hours


• resolves within first week


• more common in post term infants

**dry newborn skin


• generalized superficial desquamation within first 24-48 hours


• resolves within first week


• more common in post term infants

erythema toxic neonatorum

**small papules, vesicles, or pustules surrounded by blotchy erythema; can resemble herpes


• appears in first week; disappears within 1-2 weeks


• filled w/ eosinophiles on smear

**small papules, vesicles, or pustules surrounded by blotchy erythema; can resemble herpes


• appears in first week; disappears within 1-2 weeks


• filled w/ eosinophiles on smear

miliaria

**heat rash, sweat glands become occluded


• if occlusion is deeper >> miliaria rubra


• if symptomatic >> topic antibiotics

**heat rash, sweat glands become occluded


• if occlusion is deeper >> miliaria rubra


• if symptomatic >> topic antibiotics

sebaceous hyperplasia

**small white/yellow papules on nose, <0.5 mm


• hyperandrogenous state

**small white/yellow papules on nose, <0.5 mm


• hyperandrogenous state

milia

**pearly white/yellow papules; ~1 mm


• usually brow, cheek, & nose


• epidermal cyst caused by accumulation of sebaceous gland secretions


• resolve spontaneously during first weeks


• epstein pearls when found in mouth; will ...

**pearly white/yellow papules; ~1 mm


• usually brow, cheek, & nose


• epidermal cyst caused by accumulation of sebaceous gland secretions


• resolve spontaneously during first weeks


• epstein pearls when found in mouth; will usually go away as infants suck

sucking bister

**vesicles or bullae on lips, fingers, hands


• result of vigorous sucking


• require no treatment


• r/o herpes w/ mom's history

**vesicles or bullae on lips, fingers, hands


• result of vigorous sucking


• require no treatment


• r/o herpes w/ mom's history

harlequin color change

**lying on one side sharply demarcated red color on dependent half of body


• only seen in newborn period; up to 4-6 weeks


• common in LBW


• benign; temporary imbalance of autonomic regulatory mechanism of cutaneous vessels

**lying on one side sharply demarcated red color on dependent half of body


• only seen in newborn period; up to 4-6 weeks


• common in LBW


• benign; temporary imbalance of autonomic regulatory mechanism of cutaneous vessels

transient neonatal pustular melanosis (TNPM)

• superficial, vesiculopustular lesions


• rupture within 12-48 hours >> leaves small pigmented macules surrounded by white scales


• remains up to 3 mos


• aspiration reveals neutrophils & almost no eosinophils

• superficial, vesiculopustular lesions


• rupture within 12-48 hours >> leaves small pigmented macules surrounded by white scales


• remains up to 3 mos


• aspiration reveals neutrophils & almost no eosinophils

mongolian spots

• hyperpigmented macule


• 90% AA, asian, hispanic


• melanocytes infiltrate dermis >> fade over first three years

hemangioma of infancy (HOI)

• most common in white newborns


• grow rapidly within first five months


• no interventions in most cases

• most common in white newborns


• grow rapidly within first five months


• no interventions in most cases

T/F. Involution of hemangioma will result in perfectly normal skin.

False; may leave silver/gray coloring

Which hemangiomas will involute?

will involute--


• HOI



will not involute--


• NICH- non-involuting congenital hemangiomas


• VM- venous malformations are progressive

T/F. Hemangiomas near the eye, mouth, and airway need to be treated.

True; dangerous to vision & airway

hemangioma treatments

1/ prednisolone PO--


• 3-5 mg/kg/day


• 3-18 mos treatment


• mood changes & HTN common


• urosepsis in female infant



2/ propranolol PO--


• 2 mg/kg/day TID w/ meals


• early referral by week 6



3/ laser by dermatology

dacryostenosis

**congenital nasolacrimal duct obstruction


• intermittent to constant tearing or visible drainage


• unilateral or bilateral


• dacryocystitis


• 73% of term infants >> 90% resolves spontaneously

dacryostenosis exam & treatment

exam--


• firm blue/gray swelling in nasolacrimal area


• eye exam is normal



treatment--


• moist warm soaks, massage 4-6x per day


• ophthalmology referral if unresolved @ 12 months

dacryostenosis differential

• excessive tearing


• foreign body


• corneal abrasion


• glaucoma


• rhinorrhea w/ tearing


• chlamydia conjunctivitis

oral candidiasis

**thrush; white plaques that doesn't come off


• inflamed buccal mucosa


• may be a/w cutaneous candidiasis in diaper area


• recurrent/severe >> s&s of HIV disease or immune deficiency


• both mom & baby should be treated; treat mom to air dry

thrush history & treatment

history--


• fuzzy, can be asymptomatic


• maternal HIV infection


• recent antibiotic use



treatment--


• nystatin


• flucanazole

congenital stridor

**high-pitch upper airway crowing


• laryngotracheomalacia (ENT)


• subglottic stenosis

congenital stridor history & PE

history--


• onset, severity, condition


• risk factors, i.e. intubation, birth trauma, GERD



PE--


• retractions


• cyanosis, apnea


• poor feeding >> FTT


• identify lesion site

stuffed nose & URI treatment

• normal saline nose drop/spray


• nasal aspirator

respiratory red flags

• tachypnea; >60-65 bpm


• retractions, grunting


• cyanosis RA


• noisy or decreased auscultation

congenital malformations

• choanal atresia/stenosis


• micrognathia w/ or w/o cleft palate


• congenital laryngeal or tracheal stenosis


• severe tracheomalacia


• diaphragmatic hernia


• pulmonary hypoplasia


• congenital lobar emphysema

transient tachypnea of newborn (TTN)

patho--


• rapid breathing caused by alveolar retention of amniotic fluid


• more common in GDM & c-section


• gets better w/ time


 


s&s--


• minimal O2 needs


• precipitated by cold stress


• streaky fluid l...

patho--


• rapid breathing caused by alveolar retention of amniotic fluid


• more common in GDM & c-section


• gets better w/ time



s&s--


• minimal O2 needs


• precipitated by cold stress


• streaky fluid line on chest xray

chlamydia conjunctivitis

• c. trachomatis causes neonatal conjunctivitis, trachoma, pneumonia


• typically develops 5-14 days s/p birth


• lasts 2 weeks


• watery to mucopurulent eye discharge


• pseudomembrane w/ bloody discharge



treatment--


• routine prophylactic drops of silver nitrate


• erythromycin 50 mg/kg QID x2weeks PO

chlamydia pneumonia

• 2-19 weeks


• preceding signs include rhinorrhea, congestion, & conjunctivitis


• tachypnea w/ persistent staccato cough


• congestion, rales, & rare wheezing


• preterm infants can have apnea

What is the gold standard for diagnosis chlamydia pneumonia?

Culture is highly specific and sensitive, containing epithelial cells. Chest x-ray is vague and show hyperinflation and infiltrates.

chlamydia pneumonia treatment

erythromycin

pneumothorax etiology & clinical features

etiology--


• spontaneous or a/w meconium aspiration


• bacterial pneumonia


• sepsis


• respiratory distress syndrome


• resuscitative measures



s&s--


• (-) breath sounds w/ or w/o mediastinal shift


• clear area w/ distinct margin & absent lung sounds


• non-distressed tachypnea


• retractions

pneumothorax nontension v. tension

Non-tension can be watched whereas tension pneumothorax may require a chest tube.

pneumothorax diagnostic evaluation

• pass catheter into nares to r/o choanal atreasia


• abdomen- r/o scaphoid >> diaphramatic hernia


• inspect oropharynx & neck


• chest x-ray

• pass catheter into nares to r/o choanal atreasia


• abdomen- r/o scaphoid >> diaphramatic hernia


• inspect oropharynx & neck


• chest x-ray