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86 Cards in this Set
- Front
- Back
The factor that has the greatest effect on basal energy expenditure is? |
Fat free mass |
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A valuable technique for measuring total energy expenditure is... |
The double labeled water technique |
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The thermic effect of food is the |
Increase in energy expenditure associated with digestion, absorption, and metabolism of food |
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The effect of caffeine, nicotine, and metabolic rate is as |
stimulants |
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What are the three components of total energy expenditure? |
Basal Energy Expenditure Thermic Effect of Food Activity thermogenesis |
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What is BMR |
minimum amount of energy expenditure that is compatible with life |
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What percentage does BMR have on total energy expenditure? |
60-70% |
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What is the difference between resting metabolic rate and BMR |
More commonly used that BMR, basically the same thing, usually 10-20% higher than BMR |
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What are some factors that affect RMR? |
Age Body Composition (Fat free mass vs body mass index and high metabolic organs) Hormonal status Temperature Caffeine, nictotine, and alcohol |
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How does chronic fever effect RMR? specifically how much |
increases energy needs 7% each degree above 98.6 |
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What percentage of Total Energy Expenditure is the thermic effect of food? |
10% |
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What are factors that effect the thermic effect of food? |
Increased after consumption of CHO and protein as opposed to fat Spicy foods increase and prolong effect (33% for 3 hours) |
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What does NEAT stand for? |
Non-exercise activity thermogenesis (workday, shopping, fidgeting) |
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What is direct calorimetry? |
Monitors the amount of heat produced by a person inside of a structure big enough for physical activity. Provides no info on kind of fuel being oxidized Seldom used |
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What is indirect calorimetry? |
Estimates energy expenditure by measuring oxygen consumed and co2 produced. The gold standard |
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What is the best formula for estimating RMR? |
Mifflin St. Jeor |
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What is a downfall of Mifflin St. Jeor's formula? |
underestimates obese |
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What are the steps in the determining nutrition status? |
Nutrition screening--> nutrition assessment --> Nutrition status |
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What is nutrition screening? |
the process used to identify nutritional problems or risk factors |
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What is the goal of nutrition screening? |
Quickly identify individuals who warrant a more detailed assessment (5-10 minutes) |
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Who performs nutrition screening? |
diet tech, nurse, physician or other qualified health professionals. Once completed those at nutritional risk are referred to the RD. This is cost effective. |
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Screening usually includes |
degree of weight loss, current need for nutrition support, skin breakdown, poor intake, chronic us of diets |
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What is the first step in the Nutrition Care Process? |
Nutrition Assessment |
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What is nutrition assessment? |
Comprehensiveevaluation carried out by a registereddietitian for defining nutrition statususing medical, social, nutrition, and medication histories; physicalexamination; anthropometric measurements; and laboratory data. (RD interpretation of screening) |
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What are three goals of nutrition assessment |
1. identify individuals who require aggressive nutrition support 2. Restore or maintain an individual's nutrition wellness 3. Identify appropriate MNT (Intervention) (Provides the Basis for the Nutrition Diagnosis) |
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Nutrient intake analysis; definition, advantages, and disadvantages |
72 calorie count hospital setting Advantages: Actual observation Disadvantages: doesn't reflect possible variation in portion sizes, or reflect intake of free living ind. |
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Daily food record/diary; advantages, and disadvantages |
Advantages: Provides daily records or food intake. Can provide info on quantity of food, prep, and timing. Disadvantages: Literacy of patient, ability to measure or judge portion sizes. Influenced by the recording process. |
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Food frequency: advantages, and disadvantages |
Advantages: Easily standardized. Beneficial when considered in conjunction with usual intake. Disadvantages: Literacy skill. Doesn't show meal patterns. Ability to measure portions. |
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24 hour recall |
Advantages: quick and easy Disadvantages: Relies on memory, ability to measure portions, doesn't reflect usual intake, interviewing skills necessary |
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The purpose of nutrition screening is? |
quickly identify individuals who are malnourished or at a nutritional risk |
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Retrospective methods for collecting dietary intake data include? |
food frequency questionaires |
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What are laboratory test's used for in the nutrition care process? |
Diagnose disease Support nutrition diagnoses Monitor nutrition intervention |
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What is the only objective data used in the nutrition care process? |
Lab data |
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What are static testing procedures? |
Measuring actual level of nutrient in the specimen Specimen nutrient concentrations do not reflect the amount of the substance stored in body pools that are not sampled Influenced by recent dietary intake (requires fasting) |
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What are functional testing procedures? |
Measures activity that depends on the nutrient of interest |
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What is hypOvolemia |
Loss of water and electrolytes leading to ECF volume contraction |
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What is hypERvolemia |
ECF volume expansion Fluid overload in the intravascular compartment occurs to an increase in total body SODIUM content NOT overhydration your body is retaining water not over consumption |
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What happens to lab results during hypOvolemia? |
They all increase Fluid is in a contracted state, everything is concentrated |
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What happens to lab results during hypERvolemia? |
They all decrease Retaining fluid, lab values are being diluted by excess fluid |
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C-reactive protein is a ______ biomarker |
inflammatory; identifies when inflammatory response |
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When C-reactive protein is high the body is ______ |
catabolic |
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What are some positive acute phase responders? |
C- Reactive Protein Ferritin |
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What are some negative acute phase responders? |
Albumin Transferrin Prealbumin Retinol Binding Protein |
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All negative acute phase responders _______ with inflammation |
Decline with inflammation and thus do not reflect current dietary intake or protein status |
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Creatine is used along with _____ to assess kidney function, drawn from _______ |
BUN blood |
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What does low albumin imply? During inflammation? |
albumin low? Sometimes consideredmalnutrition.. Not a good assumption. If you have a liver disease its nevergoing to make albumin like it used to, because the liver makes albumin. If youare inflammatory, it will still be low. Water in plasma moves to the interstitial compartment and promotes edema |
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what is the major purpose of albumin? |
Maintains colloidal osmotic pressure of the plasma |
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Retinol Binding Protein compared to albumin and prealbumin |
Not as effected by inflammatory stress |
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Transferrin's role |
Transportsiron to the bone marrow for production of Hgb |
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Plasma transferrin level controlled by |
size of iron storage pool |
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Hematocrit |
Measure of the % of RBC's in total blood volume |
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Total Iron Binding Capacity |
Measure of all protein available to bind mobile iron and depends on the number of free binding sites transferrin Sinceiron moves through the blood attachedto transferrin,tells how well that protein can carry ironin the blood |
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Transferrin saturation low/high and TIBC low/high with iron deficiency |
Transferrin low TIBC high |
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Hemoglobin |
¡Quantifiestotal Hgbin RBCs rather than a % of total blood volumeàmore direct measure of Fe than Hct |
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Ferritin |
Storageprotein that contains theiron normally gathered in the liver, spleen and marrow. Indicator of the size of body's iron storage pool |
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As iron goes up/down ferritin goes up/down |
Iron stores increase ferritin increases |
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Ferritin is an acute phase protein --> value increase/decrease in presence of inflammation |
increase Thus not a reliable indicator of irons stores in acute inflammation |
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Is the lab value of iron reliable? |
no large day to to day changes |
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What are the three types of anemia? |
Microytic Macroytic Normoytic/Anemia of Chronic Disease |
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Microytic Anemia |
Associated with iron deficiency Small pale cells |
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Macroytic Anemia |
Associated with folate and B12 deficiency Few large cells, filled with Hgb |
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Normocytic/Anemia of Chronic Disease |
Associated with rheumatic disease, CHF, chronic infection, and cancer |
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Assessing folate and vitamin b12 metabolic function |
serum homocystein.. if either are low it will build up |
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RBC folate reflects.... |
tissue stores and most reliable indicator of folate status |
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Serumproteins that decrease during the acute-phase response (negative acute-phaserespondents) include |
albumin,transferrin, and retinol-binding protein. |
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Acutelyill patients experiencing inflammatory stress would be expected to have highserum levels of |
c reactive protein |
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Anemiacaused by deficiencies of folate or vitamin B12 isusually |
macrocytic |
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The Schilling test is used to |
detect defects in vitamin B12 absorption. |
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Tetracycline |
Tetracycline will chelate with calcium from dairy foods and supplements, making both the drug and the calcium unavailable for absorption. |
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Grapefruit |
increases/decreases intestinal metabolism of drugs Fruit and juice inhibit the cytochrome enzyme which is responsible for the oxidative metabolism of many drugs can last for 72 hours |
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Phenytoin |
Can increase the metabolism of a nutrient causing it to pass through the body faster is an anticonvulsantonly free fraction drug is able to leave the serum and exert the drugs effect on the target organs, people with albumin levels <3 g/dL will need a lower dose of phenytoin |
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Loop diuretics |
Increase the excretion of potassium, magnesium, sodium, chloride, and calcium long term use need supp. Mg and Ca |
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MAOI inhibitors |
Alter the intended pharmacologic action of a medication by enhancing the medication effects Signifigant ingestion of high Tyramine foods while on MAOI can cause hypertension crisis |
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Coumadin/Warfarin |
Inhibits action of drugs Vitamin K opposes the action of warfarin and allows the production of more clotting factors |
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creatine |
urine= muscle protein blood= kidney function (filtration) if kidney is not functioning right build up of creatine |
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Prealbumin |
Transports thyroid hormone has a half life of 2 days |
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Retional Binding protein |
Best way to test.. |
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Transferrin |
controlled by iron stores transports iron for Hmg production |
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Hemotocrit vs Hemoglobin |
Hemo is % of Hmg in total blood volume Hmg is the total amount in body |
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TIBC(Total Iron Binding Capacity) |
depends on transferrin trans down TIBC up |
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Ferrtin |
indicator of the body's iron storage pool values increase during inflammation |
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Serum homocysteine is a biomarker of.... but _____ is better for folate and ____ better for .... |
B12 or folate low it will build up but RBC folate better Shillings test better for b12 |
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Who credentials? DPD and RD's |
Acend during DPD CDR once you are a RD |
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what are the six criteria of malnutrition |
1. insufficient energy intake 2. weight loss 3. loss of muscle mass 4. Loss of subcutaneous fat 5. Localized or general fluid accumulation 6. Diminished functional state (hand grip) |
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low levels of albumin effect on drugs (malnutrition) |
fewer binding sites for protein bound drugs , increased action of the drug |
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Iron absorption goes up or down with food |
down 50 percent |