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15 Cards in this Set

  • Front
  • Back
Why Study immunology?
1.) Infectious Diseases
2.) Mechanisms of pathogenicity
- Virulence factors
3.) Vaccine development
What are the diseases that are caused by a disturbed immune system?
1.) Allergy
2.) Autoimmunity
The immune response to innocuous materials (allergens).

ex.) Asthma
Allergy
Immune responses to transplanted tissue.
Graft Junction
What is the definition of Immunodeficiency?
Defects in immune responses

Ex.) CMI, T-Cells, B-Cells, Complement, and phagocyte deficiencies.
What are 2 manipulations of immunity to treat disease?
1.) Immunosuppression: Treatment of immune diseases

2.) Immunoregulation: Immunotherapeutic interventions
1.) 1st line of Defense
2.) 2nd line of Defense
3.) 3rd line of Defense

a.) Cellular and humoral defenses (innate)
b.) Skin & Mucous membranes
c.) Cellular and humoral defenses (acquired)
1.) b
2.) a
3.) c

*the cold virus can escalade to pneumonia because it inhibits the actions of the 1st line of Defense (rapidly regenerating surfaces, peristaltic movement, mucociliary escalator, etc.)
Anatomical defenses, inflammation, fever, and phagocytic barriers are involved in what type of immunity?
Innate (natural) immunity: Inbuilt immunity to resist infection.
Specificty, Tolerance, and Memory are involved in what type of immunity?
Acquired (adaptive) immunity: Immunity established to adapt to infection.
Cells, proteins and supporting systems that kill or inactivate invaders (such as bacteria, viruses, fungi, and protozoa), reacts to chemicals and allergens, and monitor ever cell in the body for cancer.
The immune system
What are the advantages to the Immune system?
1.) Kills Bacteria
2.) Kills cells infected w/ bacteria or viruses
3.) Inactivates or destroys viruses
4.) Inactivates or destroys toxins, kills cancer cells
What are the disadvantages to the Immune system?
1.) Contributes to allergies
2.) Rejects transplanted tissues
3.) Sometimes mistakenly attacks itself, Autoimmune diseases
T or F. An antigen is a substance that illicits an immune response and can be of any size.
False. The substance has to be greater than 10,000 MW in order to be am antigen.
What is an important aspect to a vaccine?
The immune system detects antigens regardless of its source.
What are the components of a microbe that are antigen?
Proteins, cell membrane, cell wall, and envelope.