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47 Cards in this Set

  • Front
  • Back

Is the innate immune response specific or non- specific?

Non specific

What is the player of skin where dead cells and and keratin can be found?

stratum corneum

What type of cells create mucus?

goblet cells

how does h. pylori work?

breaks down mucus in stomach and exposes lining of the stomach to the stomach acid causing ulcers

what do lysosomes do?

break down cell walls of bacteria

what antibody does the lacrimal apparatus contain?

Ig A

what are lipocalins?

A family of proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids

what is the ciliary escalator?




anatomy?

prevents particles and bacteria from entering lungs




9 dublets center

what happens in the disease pertussus?

cilia sheds (from throat)

what do lysosomes in tears do?

they bind to iron and makes it limited to bacteria and also flushes out the corea

this is found on the skin and is an unsaturated fatty acid with a low ph...

sebum

perspiration contains lysosomes and ___________.

salt

gastric secretions maintain a low pH that kills bacteria in the stomach what is it?

1-3 pH

give 2 examples of microbial antagonism:

lactobacillus in vagina




e. coli in colon



what are transferring/ ferretins?

iron binding plasma proteins




(virulence factor)

what are siderophores?

iron binding proteins that are produced by bacteria

lymphocytes, phagocytes and antibodies are all part of what body system?

lymphatic

what does the thymus do?

matures under developed t cells

what does the spleen do ?

- filters pathogens in blood ( macrophage)


- removes old blood cells


- stores 240 ml of blood



are lymphocytes adaptive yes/ no?

yes slightly adaptive

what are the 3 types of granulocytes?

neutrophils


basophils


eosinophils



what is the most abundant leukocyte in the body?

neutrophils


70 %

what is diapesis?

when rbc's leave the vessel

true or false nuetrophils are phagocytic?

true

what is pus?

caused by bacteria, primarily dead neutrophils

these leukocytes tend to release when there is a parasitic infection:

eosinophils

eosinophils make up what percentage of wbc's?

1-6

this agranular wbc is an antigen presenting cell:

monocyte

what are PAMPs?

Pathogen presenting molecular patterns




- peptidoglycan


- lipopolysaccharide


- dsRNA

these 2 types of inflammatory mediators are released by wbc's:

cytokines and chemokines

interleukin 12:

activates nk cells

interleukin 6:

increases antibody activity

TNF a:

increases vascular permeability

CXC- L8:

attracts defensive cells to site of infection

what do cytokines and chemokine do?

- release wbc due to infection


- regulate inflammation and immune resp

what is a norm response to tissue damage?

inflammation

what causes the redness and heat during inflammation?

vasodilation



what causes the swelling and pain during inflammation?

blood vessel permeability

describe phagocytic migration?

- neutrophils and monocytes migrate to inf


- stick to inner lining of vessels


- pass into surrounding and engulf microorg.


- chemotaxis



how many types of interferon are there?

3




A


B


Lambda

when are the genes for interferon production produced?

when the cell is infected

what are interferons?

antiviral proteins that interfere with viral replication

how do interferons stop viral replication?

indirectly by activating genes for antiviral proteins

what is the compliment system?



process that activates inflammatory response



what are the 26 proteins in the liver called?

serum

all bacteria are partially _______ charged? Why?

-




to allow antimicrobial proteins that are + charged to bind to them

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