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71 Cards in this Set

  • Front
  • Back

symbiosis

-a relationship in which two organisms live together

commensalism

-type of symbiosis


-one organism benefits and the other remains unharmed

parasitism

-type of symbiosis


-one organism benefits (parasite) and other is harmed (host)

mutualism

-type of symbiosis


-both organisms benefit

neutralism

-type of symbiosis


-neither organism benefits

colonization

-condition in which presence, growth, and multiplication of microorganism on or in host have no clinical effect and no detectable immune response

infection

-condition in which presence, growth, and multiplication of microorganism on or in the host elicit some form of response, either clinical or immunological

sub-clinical infection

-immune response developed without overt signs or symptoms

normal flora

-organisms that normally populate a body site without causing disease


-generally commensalistic or mutualistic relationships


-remain for life but change in response to internal environmental alterations

disease

-disorder recognizable by a specific set of signs and symptoms

virulence

-power of an organism to cause disease


-depends on toxigenicity and dose

invasiveness

-ability to penetrate and overcome host defenses

toxigenicity

-ability to produce toxins

dose

-number of organisms required to start the disease process

pathogenicity

-organism's ability to cause disease

obligate pathogens

-pathogens that will always cause disease (usually parasites)

non-pathogens

-organisms that under normal conditions will not cause disease

opportunistic pathogens

-organisms that may be normal flora under usual circumstances but may become pathogens if conditions change

immunosuppression

-specific administration of a drug therapy or disease state that interferes with immune mechanism, either humoral or cellular

immunocompromised

-person born with immune system defect, either humoral or cellular

endogenous infections

-infections caused by organisms from within patient's own normal flora

exogenous infections

-infections caused by organisms from external sources

nosocomial infections

-infections acquired during hospital stay

community-acquired infections

-infections that spread naturally through the community external to the hospital

communicable diseases

-diseases capable of being transmitted from one host to another

contagious

-diseases that spread with considerable ease

non-communicable diseases

-diseases acquired directly from the environment and cannot be transferred easily from one host to another (eg. tetanus)

endemic diseases
-diseases indigenous within a given geographic area
epidemic

-explosive outbreak within a population

pandemic

-worldwide outbreak of a disease

acute diseases

-diseases that develop rapidly, present with severe symptoms, climax and fade quickly
chronic diseases

-diseases that develop slowly, symptoms develop slowly and are sometimes vague, rarely reach climax and take months for convalescence, sometimes never really fading away

primary disease

-disease that occurs in a previously healthy body

secondary disease

-disease that develops in an already diseased body

systemic infection

-infection that has spread throughout body to many or all organs

local infection

-infection restricted to a single area of the body

direct transmission
-when a disease travels from person to person

vectors

-animate objects that transmit disease

fomites

-inanimate objects that transmit disease
congenital

-transfer of disease directly to fetus in-utero or as child passes through birth canal
air-borne transmission
-indirect mode of transmission that occurs when disease-causing organisms are inhaled
direct contact

-if disease is transmitted to new host through contact with infected individual or source
indirect contact

-occurs if source of infection is food, water, or fomites or if disease is transmitted to new host via living organisms (eg. ticks or fleas)

zoonoses

-human diseases caused by organisms that are primarily animal pathogens and accidentally are transmitted to humans

reservoir

-the source of a disease, necessary for disease to perpetuate itself

carrier

-special type of reservoir in which a person who has recovered from the disease continues to spread infectious organisms
clinical disease
-when conditions occur to an extent that the patient exhibits clinical-symptoms

subclinical disease


-when few or no obvious symptoms occur
What are the 5 stages of the disease process?

-period of incubation


-prodromal period


-acme period


-period of decline


-convalescence

period of incubation

-time between entry of organism into host and the appearance of symptoms

prodromal period


-period during which the non-specific symptoms of the disease are displayed by the patient


-great competition between host and invading organism


acme period

-display of specific symptoms of the disease

period of decline

-period directly before recovery, considered to be a crisis time, during which excessive amounts of heat are released by sweating

convalescence

-when body systems return to their normal state
What factors are important to the length of the incubation period?


-infecting dose


-organism's generation time


-organism's invasiveness and its toxicity


-portal of entry


-level of resistance in host

List some of the body's non-specific body defenses?


-skin


-mucous membranes


-stomach acidity


-vaginal acidity


-bile


-duodenal enzymes


-lysozyme


-interferons


-phagocytes, alveolar macrophages, Kupfer cells

inflammation

-dilation of blood vessels which leads to increase in capillary permeability and in phagocytic activity at site of infection

pus


-accumulation of plasma, dead cells, WBCs and bacteria both living and dead


-produced by increase in phagocytic activity during inflammation


purulent

-term describing a specimen full of pus
boil/abscess

-occurs when purulence is enclosed in a wall of fibrin and clotting process is activated

carbuncle

-collection of several abscesses
fever

-body temperature above normal body temperature, due to the effect of bacteria, viruses and other foreign organisms on the hypothalamus
humoral immunity

-specific body defense resulting in production of antibodies to antigens
cell-mediated immunity


-specific body defense that involves T-cells that can react directly with foreign antigen


-particularly involved in infections caused by parasites, viruses, rickettsia, and bacteria that are intracellular parasites

infective dose

-number of organisms that must enter body in order to establish the disease


-immunity occurs if exposure dose is less than infective dose


invasiveness
-the ability of an organism to penetrate tissues and cause structural damage

Which enzymes produced by bacteria affect their toxigenicity?

-coagulase


-streptokinase


-hyaluronidase


-leukocidin


-hemolysin

endotoxins

-toxins that are part of cell wall of Gram negative organisms and are released upon the death of the cell
exotoxins


-proteins that often behave as enzymes and are usually classified according to their activity


-predominantly produced by Gram positive organisms

By which mechanisms do bacteria overcome host defenses?


-attachment and multiplication


-retrieval of nutrients from host


-inhibition of phagocytosis


-evasion of immune response


-damage to host tissues


-indirect damage to host tissues through an immune reaction