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328 Cards in this Set

  • Front
  • Back
Infant deprivation effects: What are the effects of Infant deprivation(ID) ?
1. decreased muscle tone 2. poor language skills, 3.poor socialization 4 lack of basic trust, 5. Anaclitic depression, 6. weight loss 7. physical illness [Anaclitic: Psychological dependence on others]
Infant deprivation effects: The four W's are used to describe the effects of infant deprivation?
Weak, Wordless, Wanting (socially), Wary
Infant deprivation effects: Complication of severe infant deprivation?
For longer than 6months - changes may be irreversible. Infant death is possible with severe deprivation.
Anaclitic depression: What is Anaclitic depression?
Depression in an infant due to continued separation caregiver? Results in withdrawal and unresponsiveness.
Regression in children: Cause of regression in a child?
common in children under stress. E.g toilet trained child who bedwets when hospitalized
childhood early-onset disorders (p. 133): True or false: Children with ADHD have normal intelligence
TRUE
childhood early-onset disorders (p. 133): What is the treatment for ADHD
Methyphenidate (ritalin)
childhood early-onset disorders (p. 133): What is the name given to continued behavior violating social norms?
Conduct disorder
childhood early-onset disorders (p. 133): What is oppositional defiant disorder?
A noncompliant child in the absence of criminality
childhood early-onset disorders (p. 133): What is the age of onset of tourette's syndrome?
Before 18
childhood early-onset disorders (p. 133): What is the treatment for tourette's syndrome?
Haloperidol
childhood early-onset disorders (p. 133): What is the name given to a fear of loss of attachment figure leading to factitious physical complaints?
Seperation anxiety disorder
childhood early-onset disorders (p. 133): What is the typical age for seperation anxiety disorder?
7 or 8
childhood early-onset disorders (p. 133): What disorder is characterized by repetitive behaviors, unusual abilities, and below normal intelligence?
Autism
pervasive developmental disorders : What are the characteristics of Autism? Do they have normal intelligence?
repetitive behavior, language disability, and social problems; no
pervasive developmental disorders (p. 133): What is the treatment for autism?
Communication skill and social skill training
pervasive developmental disorders (p. 133): What is the name of a mild form of autism? Do they have normal intelligence?
Asperger syndrome: Like autism (repetitive behavior and lack of social skills) but language abilities are intact. No
pervasive developmental disorders (p. 133): True or false: Children with aspberger's syndrome has normal intelligence and lack social or cognitive defects?
TRUE
pervasive developmental disorders (p. 133): What is the only X-linked childhood personality disorder?
Rett disorder
pervasive developmental disorders (p. 133): Rett syndrome starts at which age?
4
pervasive developmental disorders (p. 133): What are the symptoms fo rett disorder?
Loss of development, and mental retardation?
pervasive developmental disorders (p. 133): Why does Rett disorder appear only in women?
Male fetuses die in utero.
Child abuse: List evidence of physical abuse in a child.
Healed fractures(xray) Cigarette burns Hematoma, multiple bruises Retinal hemorrhage or detachment
Child abuse: In physical child abuse - who is normally the abuser?
Usually female and the primary caregiver
Child abuse: Number of yearly child abuse related deaths?
3000/yr (USA)
Child abuse: List evidence of sexual abuse in a child.
Genital, anal trauma STDs, UTI
Child abuse: In sexual child abuse - who is normally the abuser?
Known to victim, usually male
Child abuse: What is the peak incidence of sexual abused (age range)?
9-12 years of age
Developmental milestones (motor, cog/social): DEVELOPMENTAL MILESTONES
p 124
Developmental milestones (motor, cog/social): (list motor and cognitive/social milestones for each age)
0
Developmental milestones (motor, cog/social): 3months
Motor: Holds head up, Moro reflex disapear Cog/Social: Social smile
Developmental milestones (motor, cog/social): 4-5mo
Motor: Rolls front to back, sits when proped Cog/social: Recognizes people
Developmental milestones (motor, cog/social): 7-9mo
Motor: sits alone Cog/social:Stranger anxiety,recognize voices
Developmental milestones (motor, cog/social): 12-14mo
Motor:Babinski disapears
Developmental milestones (motor, cog/social): 15mo
Motor: walks Cog/social:few words, separation anxiety
Developmental milestones (motor, cog/social): Toddler
0
Developmental milestones (motor, cog/social): 12-24mo
Motor: climbs stairs, stacks 3 blocks Cog/Social: Object permanence
Developmental milestones (motor, cog/social): 18-24
Motor: Stacks 6 blocks Cog/social: Raprochement
Developmental milestones (motor, cog/social): 24-48mo
Cog/social: parallel play
Developmental milestones (motor, cog/social): 24-36mo
Cog/social: Core gender identity
Developmental milestones (motor, cog/social): Preschool
0
Developmental milestones (motor, cog/social): 30-36mo
Cog/social: Toilet training
Developmental milestones (motor, cog/social): 3yrs
Motor: rides tricycle, copies line or circle drawing Cog/Social: Group play
Developmental milestones (motor, cog/social): 4yrs
Simple drawing (stick figure), hops on 1foot Cog/social: co-operative play
Developmental milestones (motor, cog/social): School age
0
Developmental milestones (motor, cog/social): 6-11yrs
Cog/Social: Development of conscience (superego), same-sex friends, identification with same sex parent.
Developmental milestones (motor, cog/social): Adolescence (Puberty)
0
Developmental milestones (motor, cog/social): 11yrs(girls) , 13yrs(boys)
Abstract reasoning (formal operations), formation of personality.
Neurotransmitter changes with Disease : Determine what NT increase or decrease with listed disease.
0
Neurotransmitter changes with Disease : Anxiety?
increase NE, decrease serotonin (5'HT) decrease GABA
Neurotransmitter changes with Disease : Depression?
decrease NE, decrease serotonin
Neurotransmitter changes with Disease : Alzheimer's dementia?
decrease Ach
Neurotransmitter changes with Disease : Huntington's disease?
decrease GABA, decrease Ach
Neurotransmitter changes with Disease : Schizophrenia?
Increase dopamine
Neurotransmitter changes with Disease : Parkinson's disease
decrease dopamine
Orientation (Psychiatry) : How can you elicit if a patient is orientated?
1. Patient's ability to know name, date and time, what his or her present circumstnces are
Orientation (Psychiatry) : Arrange (Place, time, Person) from 1st to last - in orientation loss.
1st: Time 2nd:Place Last:Their name
Orientation (Psychiatry) : What is Anosognosia?
Unaware that one is ill
Orientation (Psychiatry) : What is Autotopagnosia?
Unable to locate one's own body parts.
Orientation (Psychiatry) : What is Depersonalization?
Body seems unreal or dissociated
Amnesia types : What is Anterograde amnesia?
Inability of remember things that occurred after a CNS insult (no new memory)
Amnesia types : What is Korsakoff's amnesia? Associated behaviours?
A classic anterograde amnesia - caused by thiamine deficiency. Is associated with confabulations.
Amnesia types : In Korsakoff's amnesia - what CNS structure is destroyed? What population is it is most prevelant in?
Bilarteral destruction of Mammilary bodies. Alcoholics
Amnesia types : What is Retrograde amnesia?
Inability to remember things that occurred before a CNS insult.
Amnesia types : What type of amnesia is a complication of ECT (electroconvulsive therapy)?
Retrograde amnesia
Delerium & Dementia (p. 129): What are the symptoms of delerium?
Decreased attention span and arousal, disorganized thinking, hallucinations, illusions, misperceptions, disturbance in sleep-wake cycle, cognitive dysfunction
Delerium & Dementia (p. 129): What is the pattern of onset of delerium?
Rapid onset, waxing and waning.
Delerium & Dementia (p. 129): What is the most common psychiatric illness on medical and surgical floors? Is it reversible?
Delirium; reversible
Delerium & Dementia (p. 129): What class of drugs is associated with delerium?
anticholinergics
Delerium & Dementia (p. 129): What are the symptoms of dementia?
Gradual loss in cognition: Multiple cognitive deficits- memory, aphasia, apraxia, agnosia, loss of abstract thought, behavioral or personality changes, impaired judgement.
Delerium & Dementia (p. 129): What are the differences between delerium and dementia?
Dementia: alert patient, gradual onset,normal EEG. Delirium: rapid onset, abnormal EEG.
Delerium & Dementia (p. 129): Dementia may mimic what other illness in the elderly?
Depression
Hallucination vs. illusion vs. delusion (p.133): What is a hallucination?
A perception in the absence of actual external stimuli.
Hallucination vs. illusion vs. delusion (p.133): What is an illusion?
A misinterpretation fo actual external stimuli
Hallucination vs. illusion vs. delusion (p.133): What is a delusion?
A false belief that is not shared with other members of culture or subculture, which is firmly maintained in spite of evidence to the contrary
What is a loose association?
Disorders in the form of thought (the way ideas are tied altogether
Hallucination vs. illusion vs. delusion (p.133): True or false: A delusion is a disorder in the content of thought?
TRUE
Hallucination vs. illusion vs. delusion (p.133): True or false: A loose association is a disorder in the form ot thought?
TRUE
Dissociative fugue: what is it? What does it lead to? Is it a result of substance of abuse or general medical conditon?
abrupt change in geogrphic location with inability to recall past, confusion about personal idetntity, or assumption of a new identity. Leads to distress or impairment. Not the result of substance about or general medical condition.
Hallucinations (p. 133): True or false: Visual hallucinations are rare in schizophrenia?
FALSE
Hallucinations (p. 133): What type of hallucination occurs as an aura of psychomotor epilepsy?
Olfactory
Hallucinations (p. 133): What type of hallucination is rarest?
Gustatory
Hallucinations (p. 133): What type of hallucination is common in DT's and in cocaine abusers?
Tactile
Hallucinations (p. 133): What type of hallucination occurs while going to sleep?
Hypnagogic
Hallucinations (p. 133): What type of hallucination occurs while waking from sleep?
Hypnopompic
Schizophrenia: what are the characterics?
periods of psychosis and disturbed behavior with a decline in functioning
Schizophrenia: periods of psychosis and disturbed behavior last how long? What is it called if lasts for 1-6 months? Less then one month?
6 months; schizophreniform disorder; brief psychotic disorder, usually stress related.
Schizophrenia: 4 positive symptoms?
hallucinations (often auditory), delusions, disorganized or catatonic disorder (strange behavior), disorganized though (loose associations)
Schizophrenia: 4 negative symptoms?
flat affect, social withdrawal, Lack of speech of thought, lack of motivation
Schizophrenia: 5 subtypes
disorganized (with regard to speech, behavior, and affect), catatonic (automatisms), paranoid (delusions), undifferentiated (elements of all types), residual
Schizophrenia: etiology
genetic factors outweigh environmental factors
Schizophrenia: lifetime prevalence
1.5%; males=females; blacks=whites.
Schizophrenia: different presentation in men and women
presents earlier in men
Schizophrenia: schizophrenia +a major depressive, manic, or mixed (both) episode is called?
schizoaffective disorder
Schizophrenia: 2 subtypes of schizoaffective disorder
bipolar or depressive
Schizophrenia: Structural theory of the mind
C2
Schizophrenia: how many structures?
Freud had 3
Schizophrenia: primal urges, sex, aggression - things you want
Id
Schizophrenia: moral values, conscience - you know you can't have it
Superego
Schizophrenia: bridge and mediator between unconscious mind and external world - conflict mediator
Ego
Manic episode: How long must abnormally and persistently elevated mood or irritability be present for to be called a manic episode?
1 week
Manic episode: What are the symptoms of a manic episode?
Distractability, insomnia, grandiosity, flight of ideas, increase in goal directed activity or psychomotor agitation, pressured speech, thoughtlessness (DIG FAST)
Manic episode: How many of those symptoms must be present to be considered a manic episode?
3
Manic episode: True or false: A hypomanic episode does not cause marked impairment in social or occupational function or necessitate hospitalization?
TRUE
What is the drug of choice for bipolar disorder?
lithium
How many manic episodes does it take to define bipolar disorder?
1
How many hypomanic episodes does it take to define bipolar disorder?
1
What type of bipolar disorder involves hypomanic episodes? Manic episodes?
Type II; Type I
A milder form of bipolar disorder is called? How long does it have to last for?
cyclothymic disorder; lasting at least 2 years.
Major depression (p. 129): What are the two main characteristics of major depression?
Depressed mood, anhedonia (lost of interest)
Major depression (p. 129): What are the nine symptoms of depression?
Sleep disturbances, loss of Interest, Guilt or feeling of worthless ness, loss of Energy, loss of Concentration, change in Appetite/weight, Psychomotor retardation, Suicidal ideations, depressed mood (SIG E CAPS)
Major depression (p. 129): How many of those symptoms do you need and for how long?
5 symptoms for 2 weeks.
Major depression (p. 129): What is the definition of recurrant major depressive disorder?
2 or more episodes with 2 month symptom free interval
Major depression (p. 129): What is the lifetime prevalence of major depression in men?
5-12%
Major depression (p. 129): What is the lifetime prevalence of major depression in women?
10-25%
Major depression (p. 129): A mild depressive episode is called? How long does it have to last for?
dysthymia; 2 years.
Major depression (p. 129): ECT is painful, true or false?
FALSE
Major depression (p. 129): What are the side effects of ECT?
due to anesthesia: disorientation, anterograde and retrograde amnesia
Sleep in Depressed Patient: What are the major changes in sleep pattern in depressed patients?
decreased slow-wave (non REM - Delta), decreased REM latency, increased REM early in sleep cycle, increase total REM sleep, repeated nigttime awakenings, early morning awakening (important screening question)
Risk factors for suicide compleiton? Which sex succeeds at suicide and which tries more often?
SAD PERSONS: Sex (male), Age (teenage and elderly), Depression, Previous attempt, Ethanol or drug use, loss of Rational thinking, Sickness (medical illness, 3 or more prescription medications), Organized plan, No spouse (divorced, widowed, single, especially if childless), Social support is lacking. Women try more often; men succeed more often.
Panic disorder (p. 131): How long does it take a panic attack (intense fear and discomfort) to peak?
10 minutes
Panic disorder (p. 131): What are the symptoms of panic attack?
palpitations, abdominal distress, nausea, increased perspiration, chest pain, chills, and choking (PANIC)
Panic disorder (p. 131): How many of those must be present to call it a panic disorder?
4
Panic disorder (p. 131): What psychiatric disorder has a high prevalence during the step 1 exam?
panic disorder
Phobia (p. 131): What is a phobia? Trx?
Excessive or unreasonable fear cued by presence or anticipation of a specific object or entity. Trx: systematic desensitization.
Phobia (p. 131): True or false: a patient has insight into their own phobia
TRUE
Phobia (p. 131): Gamophobia is fear of what?
marriage
Phobia (p. 131): Algophobia is fear of what?
pain
Phobia (p. 131): Acrophobia is fear of what?
heights
Phobia (p. 131): Agoraphobia is fear of what?
open places (fear of being in public place or situation from which escape may be difficult)
PTSD (p. 131): What are the symptoms of PTSD?
Traumatic event is persistently reexperienced as nightmares or flashbacks
PTSD: What responses are involved?
fear, helplessness, or horror
PTSD (p. 131): How long must the symptoms last to be called PTSD?
1 month, causing distress or social/ occupational impairment.
PTSD (p. 131): PTSD often follows which disorder?
Acute stress disorder (lasts up to 2-4 weeks)
Other anxiety disorders (p.131): What is adjustment disorder
Emotional symptoms including anxiety or depression causing impairment following a psychosocial stressor (i.e. divorce, moving), lasting less than 6 months
Other anxiety disorders (p.131): True or false: general anxiety is related to a specific person, situation, or event?
FALSE
Other anxiety disorders (p.131): What are the symptoms of generalized anxiety disorder?
GI symptoms, fatigue, and difficulty concentrating
Personality (p.131): What is a personality trait?
an enduring pattern of perceiving, relating to, and thinking about the environment and oneself.
Munchausen's (p. 130): Is munchausen's syndrome involve conscious or unconscious motivation?
Unconscious.
Somatoform disorders (p. 130): What are the characteristics of conversion?
Symptoms suggest motor or sensory neurologic or physical disorder, but physical exam and tests are negative
Somatoform disorders (p. 130): True or false, somatoform disorders are more common in women?
TRUE
Somatoform disorders (p. 130): What is a prolonged pain that is not explained by an illness?
Somatoform pain disorder
Somatoform disorders (p. 130): What is the misinterpretation of normal physical findings leading to a persistent fear of serious illness in spite of medical reassurance?
Hypochondriasis
Somatoform disorders (p. 130): What are the characteristics of somatization disorder?
A variety of complaints involving multiple organ systems
Somatoform disorders (p. 130): What is the disorder where a patient believes their own anatomy is malformed?
body dysmorphic disorder
Somatoform disorders (p. 130): What is the false belief of being pregnant associated with objective physical signs of pregnancy?
pseudocyesis
What is primary gain?
What a symptom does for a patient's internal psychic economy
What is secondary gain?
What a symptom gets a patient (sympathy or attention)
What is tertiary gain?
What the caretaker gets.
Personality (p.131): What is a personality trait?
an enduring pattern of perceiving, relating to, and thinking about the environment and oneself.
Personality (p.131): True or false: a personality disorder does not cause impairment of social or occupational functioning?
FALSE
Personality (p.131): True or false: a patient with a personality disorder is aware of their problem
FALSE
Personality (p.131): What are the cluster A personality disorders?
Paranoid, schizoid, schizotypal (Weird)
Personality (p.131): What are the cluster B personality disorders?
Antisocial, borderline, histrionic, narcissistic (Wild)
Personality (p.131): What are the cluster C personality disorders?
Avoidant, obsessive compulsive, dependant (Worried)
Personality (p.131): What cluster has a genetic association with anxiety disorders?
C (worried)
Personality (p.131): What cluster has a genetic association with mood disorders?
B (Wild)
Personality (p.131): What cluster has a genetic association with schizophrenia?
A (weird)
Personality (p.131): What are the characteristics of paranoid personality disorder?
Distrust, suspiciousness, and projection as a defense mechanism
Personality (p.131): What personality disorder involves limited emotional expression, voluntary social withdrawal, content with social isolation?
Schizoid
Personality (p.131): What personality disorder involves interpersonal awkwardness, odd thought patterns and appearance?
Schizotypal
Personality (p.131): What personality disorder involves a disregard for others, crimality, and conduct disorders, and occurs more in males?
Antisocial
Personality (p.131): What personality disorder involves unstable mood and behavior, impulsiveness, emptiness, and occurs more often in women?
Borderline
Personality (p.131): What personality disorder involves excessive emotionality, somatization, attention seeking, sexually provocative, and overly concerned with appearance?
Histrionic
Personality (p.131): What PD involves grandiosity, a sense of entitlement ,may react to critism with rage?
Narcissistic
Personality (p.131): What PD is sensitive to rejection, socially inhibited, timid, and has feelings of inadequacy?
Avoidant
Personality (p.131): What PD is preoccupied with order, perfectionism, and control?
Obsessive-compulsive
Personality (p.131): What PD is submissive and clinging, excessively needs to be taken care of, and has low self confidence?
Dependant
Personality (p.131): Characterization of Cluster A personality disorders
Odd or eccentric; cannot develop meaningful social relationships. No psychosis
Personality (p.131): Characterization of Cluster B personality disorders
Dramatic, emotional, erractic
Personality (p.131): Characterization of Cluster C personality disorders
anxious or fearful
Schizo-: Differences of the following: schizioid, schizotypical, schizophrenic, schizoaffective
schizioid, schizotypal (schizoid + odd thinking), schizophrenic (greater odd thinking than schizotypal), schizoaffective (schizpphrenia+ mood disorder)
Eating disorders (p.133): What are the symptoms of anorexia nervosa?
Excessive dieting, body image distortion, increase in exercise. Sever weight loss, amenorrhea, anemia, and electrolyte disturbances.
Eating disorders (p.133): What are the symptoms of bulimia nervosa?
Binge eating followed by self-induced vomiting or use of laxatives. Parotitis, enamel erosion, increase in amylase, and esophageal varices from vomiting
Eating disorders (p.133): True or false: Bulimia nervosa involves normal body weight?
TRUE
Substance Dependence: List the maladaptive pattern of substance dependence?
1. Tolerance, 2. Withdrawal, 3. Substance taken in larger amounts than intended., 4. Persistent desire or attempts to cutdown, 5. Lots of energy spent trying get substance, 6. Important socia, occupational or recreational activities given up or reduced because of substance use., 7. Continued use in spite of knowledge of the problems that it causes
Substance Dependence: What is the definition of substance dependence?
The presence of 3 or more maladaptive signs in 1year
Substance Abuse: Definition of substance abuse?
Maladaptive pattern leading to significant impairment or distress.
Substance Abuse: List 4 symptoms of substance abuse?
1. Recurrent use resulting in failure to fulfill major obligation at work, school or home, 2. Recurrent use in physically harzardous situations?, 3. Recurrent substance - related legal problems, 4. Continued use in spite of persistnent problems caused by use., - Only 1 or more are reguired to met the criteria of substance abuse.
Substance Abuse: definiation of withdrawal
a substance-specific syndrome with signs and symptoms often opposite to those seen in intoxiacation and not attributable to another medical condition.
Substance abuse (p. 128): Disinhibition, emotional lability, slurred speech, ataxia, coma, and blackouts are symptoms of which drug?
Alcohol
Substance abuse (p. 128): CNS depression, nausea and vomiting, constipation, pupillary constriction, and seizures are the signs of which drug?
Opioids
Substance abuse (p. 128): Psychomotor agitation, impaired judgement, pupillary dilation, hypertension, tachycardia, euphoria, prolonged wakefullness and attention, cardiac arrhythmias, delusions, hallucianations, and fever are side effects of which drug?
Amphetamines
Substance abuse (p. 128): Euphoria, psychomotor agitation, impaired judgment, tachycardia, pupillary dilation, hypertension, hallucinations, paranoid ideations, angina, and sudden cardiac death are symptoms of which drug?
Cocaine
Substance abuse (p. 128): Belligerance, impulsiveness, fever, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, homocidality, psychosis, and delerium are side effects of which drug?
PCP
Substance abuse (p. 128): Anxiety, depression, del.usions, visual hallucinations, flashbacks, and pupil dilation are side effects of which drug?
LSD
Substance abuse (p. 128): Euphoria, anxiety, paranoid delusions, perception of slowed time, impaired judgement, social withdrawl, increased appetite, dry mouth, and hallucinations are symptoms of which drug?
Marijuana
Substance abuse (p. 128): Low safety margin and respiratory depression are characteristics of which drug?
Barbiturates
Substance abuse (p. 128): Amnesia, ataxia, somnolesence, minor respiratory effects, and addictictive effects with alcohol are the characteristics of which drug?
Benzodiazepines
Substance abuse (p. 128): Restlessness, insomnia, increased diuresis, muscle twitching, cardiac arrhythmias are the side effects of which drug?
Caffeine
Substance abuse (p. 128): Restlessness, anxiety, insomnia, and arrhytmias are the side effects of whicch drug?
nicotine
Substance abuse (p. 128): A craving for cheetos and the desire to watch "old school" are the side effects of which drug?
marijuana
Substance abuse (p. 128): What are the symptoms of alcohol withdrawl?
Tremor, tachycardia, hypertension, malaise, nausea, seizures, DTs, agitation, hallucinations
Substance abuse (p. 128): What are the symptoms of opioid withdrawl?
anxiety, insomnia, anorexia, sweating, dilated pupils, piloerection, fever, rhinorrhea, nausea, stomach cramps, diarrhea, and yawning
Substance abuse (p. 128): What are the symptoms of amphetamine withdrawl?
Post use crash of depression, lethargy, headache, stomach cramps, hunger, hypersomnolence
Substance abuse (p. 128): What are the symptoms of cocaine withdrawl
Post use crash of suicidality, hypersomnolence, fatigue, malaise, severe craving
Substance abuse (p. 128): What are the symptoms of PCP withdrawl
Recurrance of symptoms due to reabsorption, with sudden onsets of severe random violence
Substance abuse (p. 128): What are the side effects of barbiturate withdrawl?
Anxiety, seizures, delerium, life threatening CV collapse.
Substance abuse (p. 128): What are the side effects of benzodiazepine withdrawl?
Rebound anxieety, seizures, tremor, insomnia.
Substance abuse (p. 128): What are the side effects of caffeine withdrawl?
Headache, lethargy, depression, weight gain
Substance abuse (p. 128): What are the side effects of nicotine withdrawl?
Irritabilty, headache, anxiety, weight gain, craving, tachycardia?
Substance abuse (p. 128): When do DT's occur?
2-5 days after last drink
Substance abuse (p. 128): What is the treatment for DTs?
Benzodiazepines
Substance abuse (p. 128): What is the sequence of symptoms experienced in DT's?
Autonomic hyperactivity --> psychotic symptoms --> confusion
Substance abuse (p. 128): What is a competetive inhibitor of heroin?
Naloxone
Substance abuse (p. 128): What diagnoses are associated with heroin addiction?
hepatitis, abscesses, overdose, hemorrhoids, AIDS, right sided endocarditis.
Substance abuse (p. 128): What drug is used for long term maintinence or heroin detox?
methadone
Alcoholism: tremor, tachcardia, hypertension, malaise, nausea, delirium tremens are symtpoms of what?
alcohol withdrawal
Alcoholism: when do you get symptoms of alcohol withdrawal?
in case of physiological tolerance and dependence when intake is interrupted
Alcoholism: what is disulfiram and how does it work?
disulfiram is a pharmacological treatment of alcoholism - negatively conditions patient against EtOH
Alcoholism: a good possible referral to sustain EtOH abstinence in alcoholics
Alcoholics Anonymous and other peer groups
Alcoholism: 3 mechanisms of EtOH action
1) interpolates into membranes --> toxic effects, partic. in brain 2) alcohol dehydrogenase converts EtOH to acetaldehyde, forms adducts with proteins and nucleic acids, converted to acetate, Ac-CoA, FA synthesis, fatty liver 3) increased NADH/NAD ratio
Complications of alcoholism: Condition in which these are seen: hepatitis and cirrhosis, pancreatitis, dilated cardiomyopathy, peripheral neuropathy, cerebellar degeneration, Wernicke-Korsakoff syndrome, testicular atrophy and hyperestrinism, and Mallory-Weiss syndrome
alcoholism
Complications of alcoholism: name histological type of cirrhosis in alcoholism
micronodular cirrhosis
Complications of alcoholism: accompanying symptoms of alcoholic cirrhosis
jaundice, hypoalbuminemia, coagulation factor deficiences, portal hypertension
Complications of alcoholism: list clinical findings in alcoholic cirrhosis besides jaundice
peripheral edema and ascites, encephalopathy, neurologic manifestations (asterixis, flaping tremor of hands)
Complications of alcoholism: What is the cause of Wernicke-Korsakoff syndrome?
thiamine (B1) deficiency, particularly in alcoholics
Complications of alcoholism: what is the presenting triad of Wernicke's encephalopathy?
psychosis, ophthalmoplegia, and ataxia
Complications of alcoholism: distinguishing features of Korsakoff's from Wernicke's
in Korsakoff, also *memory loss*, confabulation,confusion.
Complications of alcoholism: is Korsakoff's syndrome reversible?
No.
Complications of alcoholism: Tx for Wernicke-Korsakoff syndrome
IV Vitamin B1 (thiamine)
Complications of alcoholism: What is Mallory-Weiss syndrome?
longitudinal lacerations at the gastroesophageal junction caused by excessive vomiting (for ex., in alcoholism) with failure of LES relaxation that could lead to fatal hematemesis
Intelligence testing: How does the Stanford-Binet test calculate IQ?
mental age/chronological age * 100
Intelligence testing: How does the Wechsler Adult Intelligence Scale calculate intelligence?
11 subtests - 6 verbal, 5 performance
Intelligence testing: What is the mean IQ?
100, standard deviation = 15
Intelligence testing: what are the IQ values for profound, severe, and moderate to mild mental retardation?
<20, <40, and <70 (or two standard deviations below the mean)
Intelligence testing: What determines IQ scores - based on correlation?
most highly correlated with school achievement, also correlated with genetic factors
Intelligence testing: Are intelligence tests objective or projective?
objective
Classical conditioning: salivation (a natural response) is elicited by a bell (a --- stimulus) that has been associated with food (a natural stimulus), not necessarily a reward
conditioned, or learned
Operant conditioning: a particular action is elicited because it produces a ---.
reward
Operant conditioning: an action (pressing a button) is produced because, for example, a mouse wants food
positive reinforcement
Operant conditioning: an action (pressing a button) is produced because, for example, a med student wants to avoid shock
negative reinforcement - NOT punishment
Reinforcement schedules: pattern of reinforcement determines what?
how quickly a behavior is learned and extinguished if not rewarded
Reinforcement schedules: how quickly is a behavior on a continuous schedule (i.e., vending machine use) extinguished when not rewarded?
most rapidly
Reinforcement schedules: what schedule shows the slowest extinction when not rewarded?
variable ratio (gambling)
Transference and countertransference: sometimes a patient projects feelings stemming from personal life onto his or her physician, and sometimes the physician projects feelings stemming from personal life onto the patient
transference and countertransference, respectively
Topographic theory of the mind: Name the components of this theory
CPU - Conscious, Preconscious, Unconscious
Topographic theory of the mind: Conscious
what you're aware of
Topographic theory of the mind: Preconscious
what you are able to make conscious with effort (like phone number or SSN)
Topographic theory of the mind: Unconscious
what you are not aware of (what you don't know you don't know)
Topographic theory of the mind: the central goal of Freudian psychoanalysis
to make the patient aware of what is hidden in his/her unconscious
Oedipus complex: define oedipus complex
repressed sexual feelings of a child for the oposite sex parent, accompanied by rivalry with same-sex parent - described by Freud
Ego defenses: Your --- has many ---, or automatic and unconscious reactions to psychological stress.
ego defenses
Ego defenses: Name the mature ego defenses
Mature women wear a SASH: Sublimation, Altruism, Supression, Humor
Ego defenses: using ---, one replaces an unacceptable wish with a course of action similar but not conflicting with one's values
sublimation
Ego defenses: --- is unsolicited generosity toward others that alleviates guilty feelings
altruism
Ego defenses: unlike other defenses, this is a voluntary withholding of an idea or feeling from conscious awareness
supression
Ego defenses: one uses ---, or appreciates the amusing nature to alleviate anxiety-provoking or adverse situations
humor
Ego defenses: Acting out, dissociation, denial, displacement, fixation, identification, isolation, projection, rationalization, reaction formation, regression, repression, splitting are all ---.
immature
Ego defenses: the three D's of immaturity
Dissociation, Denial, Displacement
Ego defenses: by --- --- or throwing a tantrum, unacceptable feelings and thoughts are expressed through actions
acting out
Ego defenses: the extreme forms of these temporary, drastic changes in personality memory, consciousness, or motor behavior can result in multiple personalities, or --- --- ---.
dissociation; dissociative identity disorder
Ego defenses: this is a common reaction in which one avoids awareness of some painful reality
denial
Ego defenses: a mother might transfer avoided anger at her husband by yelling at her child
displacement
Ego defenses: partially remaining at a more childish level of development, like men's fascination with sports games
fixation
Ego defenses: victim of child abuse becomes abuser
identification
Ego defenses: separation of feelings from ideas and events like describing murder in graphic detail with no emotional response
isolation
Ego defenses: when a man who wants another woman thinks his wife is cheating on him, he is ---.
projecting
Ego defenses: when one wants to avoid self-blame, one might say a job wasn't important anyway after not getting it
rationalization
Ego defenses: this is described by someone with libidinous thoughts enters a monastery
reaction formation
Ego defenses: --- occurs when one turns back the maturational clock, going back to earlier modes of dealing with the world - like children in stress who wet the bed
regression
Ego defenses: involuntary withholding of an idea or feeling from conscious awareness
repression
Ego defenses: belief that people are either good or bad
splitting
Topographic theory of the mind: Name the components of this theory
CPU - Conscious, Preconscious, Unconscious
Topographic theory of the mind: Conscious
what you're aware of
Topographic theory of the mind: Preconscious
what you are able to make conscious with effort (like phone number or SSN)
Topographic theory of the mind: Unconscious
what you are not aware of (what you don't know you don't know)
Topographic theory of the mind: the central goal of Freudian psychoanalysis
to make the patient aware of what is hidden in his/her unconscious
Oedipus complex: define oedipus complex
repressed sexual feelings of a child for the oposite sex parent, accompanied by rivalry with same-sex parent - described by Freud
Antipsychotics (neuroleptics): what is another name for antipsychotics
neuroleptics
Antipsychotics (neuroleptics): name 4 antipsychotic drugs
thioridazine, haloperidol, fluphenazine, chlorpromazine
Antipsychotics (neuroleptics): how do you keep benzos straight from antipsychotics
Benzos help 3rd year Jon Kazam be less anxious around patients: Shazam Kazam! Without antipsychotics patients talk like a crazy 'zine (well, not perfect, but I'm working on it)
Antipsychotics (neuroleptics): what is the mechanism of most antipsychotics
block dopamine D2 receptors
Antipsychotics (neuroleptics): what is the clinical application of antipsychotics
schizophrenia, psychosis
Antipsychotics (neuroleptics): what are the side effects of antipsychotics
extrapyramidal side effects (EPS), sedation, endocrine, muscarinic blockade, alpha blockade, histamine blockade
Antipsychotics (neuroleptics): what is a long-term effect of antipsychotic use
tardive dyskinesia
Antipsychotics (neuroleptics): what is neuroleptic malignant syndrome
a side effect of antipsychotics; rigidity, autonomic instability, hyperpyrexia
Antipsychotics (neuroleptics): how do you treat neuroleptic malignant syndrome
dantrolene, dopamine agonists
Antipsychotics (neuroleptics): what is tardive dyskinesia
side effect of neuroleptics; stereotypic oral-facial movements, may be due to dopamine receptor sensitization
Antipsychotics (neuroleptics): what is the "rule of 4" with EPS side effects from antipsychotic drugs
evolution of EPS side effects: 4 hours -- acite dystonia, 4 days -- akinesia, 4 weeks -- akasthesia, 4 months -- tardvie dyskinesia
Antipsychotics (neuroleptics): is tardvie dyskinesia reversible
often irreversible
Antipsychotics (neuroleptics): what is fluphenazine used for
schizophrenia, psychosis
Atypical antipsychotics: name 3 atypical antipsychotics
clozapine, olanzapine, risperidone
Atypical antipsychotics: what type of antipsychotic is clozapine
atypical
Atypical antipsychotics: what type of antipsychotic is olanzapine
atypical
Atypical antipsychotics: what type of antipsychotic is risperidone
atypical
Atypical antipsychotics: what is the mechanism of atypical antipsychotics
block 5-HT2 and dopamine receptors
Atypical antipsychotics: what is the mechanism of clozapine
block 5-HT2 and dopamine receptors
Atypical antipsychotics: what is the mechanism of olanzapine
block 5-HT2 and dopamine receptors
Atypical antipsychotics: what is the mechanism of risperidone
block 5-HT2 and dopamine receptors
Atypical antipsychotics: what is the clinical application of clozapine
schizophrenia positive and negative symptoms
Atypical antipsychotics: what is the clinical application of olanzapine
schizophrenia positive and negative symptoms, OCD, anxiety disorder, depression
Atypical antipsychotics: what is the clinical application of risperidone
schizophrenia positive and negative symptoms
Atypical antipsychotics: how are atypical antipsychotics different from classic ones
atypicals treat positive and negative symptoms of schizophrenia, fewer extrapyramidal and anticholinergic side effects than classic antipsychotics
Atypical antipsychotics: which antipsychotics should be used to treat positive and negative symptoms of schizophrenia
atypical ones -- clozapine, olanzapine, risperidone
Atypical antipsychotics: which antipsychotics should be used for fewer side effects
atypical ones -- clozapine, olanzapine, risperidone
Atypical antipsychotics: what is a potential toxicity of clozapine
agranulocytosis
Atypical antipsychotics: which antipsychotic drug can cause agranulocytosis
clozapine
Atypical antipsychotics: what test must be done weekly on patients taking clozapine
WBC count because of potential agranulocytosis
Lithium: what is the mechanism of action of lithium
unknown; may be related to inhibition of phosphoinositol cascade
Lithium: what is the clinical application of lithium
mood stabilizer for bipolar disorder
Lithium: how does lithium help people with bipolar disorder
prevents relapse and acute manic episodes
Lithium: what are the side effects of lithium
tremor, hypothyroidism, polyuria, teratogenic
Lithium: is it OK for women taking lithium to get pregnant
NO -- teratogenic
Lithium: what does lithium cause polyuria
ADH antagonist --> nephrogenic diabetes insipidus
Antidepressants: What do the following drugs inhibit: 1. MAO inhibitors, 2. Desipramine/maprotilline, 3. Mirtazapine and 4. Fluoxetine/trazodone?
1. MAO 2. NE reuptake 3. Alpha 2-R 4. 5HT reuptake
Antidepressants: All of the above actions are ------synaptic
PRE
List the Tricyclic Antidepressants: What are the three C's of their toxicity?
Convulsions, Coma, Cardiotoxicity (arrythmias). Also respiratory depression, hypyrexia.
List the Tricyclic Antidepressants: How about toxicity in the eldery?
confusion and hallucinations due to anticholinergic SE
List the Tricyclic Antidepressants: What is the mechanism of TCA?
block reuptake of NE and 5HT
List the Tricyclic Antidepressants: What is the clinical uses of TCAs?
Endogenous depresion. Bed wetting - imipramine. OCD- clomipramine.
List the Tricyclic Antidepressants: How are tertiary TCA's different than secondary in terms of side effects?
Amitriptyline (tertiary) has more anti-cholinergic effects than do secondary (nortriptyline). Desipramine is the least sedating.
List the Tricyclic Antidepressants: what are the SE of TCAs?
sedation, alpha blocking effects, atropine-like anti cholinergic side effects (tachycardia, urinary retention)
List the Tricyclic Antidepressants: Fluoxetine, sertraline, paroxetine, citalopram are what class of drugs?
pg 311 SSRI's for endogenous depression
List the Tricyclic Antidepressants: How long does it take an anti-depressant to have an effect?
2-3weeks
List the Tricyclic Antidepressants: How does the toxicity differ fromTCA's and what are they?
Fewer than TCA's. CNS stimulation - anxiety, insomnia, tremor, anorexia, nausea, and vomiting.
List the Tricyclic Antidepressants: What toxicity happens with SSRI's and MAO inhibitors given together?
Seratonin Syndrome! Hyperthermia, muscle rigidity, cardiovascular collapse
List the Tricyclic Antidepressants: What are heterocyclics?
pg 312 2nd and 3rd generation antidepressants with varied and mixed mechanisms of action. Used major depression.
List the Tricyclic Antidepressants: Examples of heterocyclics?
trazodone, buproprion, venlafaxine, mirtazapine, maprotiline
List the Tricyclic Antidepressants: Which one is used for smoking cessation?
Buproprion. Mechanism not known. Toxicity - stimulant effects, dry mouth, aggrevation of pyschosis
List the Tricyclic Antidepressants: Which one used in GAD?
Venlafaxine - inhibits 5HT and DA reuptake. Toxicity - stimulant effects
List the Tricyclic Antidepressants: which one blocks NE reuptake
maprotiline
List the Tricyclic Antidepressants: Which one increases release of NE and 5HT via alpha 2 antagonism?
mirtazapine. Also potent 5HT Rantagonist. Toxicity - sedation, increase serum cholesterol, increase apetite
List the Tricyclic Antidepressants: What is trazodone and it' SE?
primarily inhibits seratonin reuptake. Toxicity - sedation, nausea, priapism, postural hypotension
Give 2 examples of MAO: Mechanism and Clinical Uses?
non selevtive MAO inhibition. Atypical antidepressant, anxiety, hypochondriasis
Give 2 examples of MAO: What is the toxicity with tyramine ingestion (in foods) and meperidine?
Hypertensive crisis
Give 2 examples of MAO: Other toxicities?
CNS stimulation, contraindicated with SSRI's or B-agonists
What is the mechanims of selgiline (deprenyl)?: what is the clinical use and toxicity?
adjunctive agent to L-dopa for Parkinsons. May enhance adverse effects of L-dopa