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22 Cards in this Set

  • Front
  • Back
What treatments are available for crohn's disease
5-ASA agents
Mesalamine, Sulfasalazine (5-ASA+Sulfa abx) <--activated in colon only
Azothioprine or Mercaptopurine> Methotrexate
Anti-TNFa (infliximab, adalimumab) <-- good for HLA-B27
Steroids
What are the MC causes for Small Bowel Obx?
ABC

Adhesions
Bulge (hernia)
Carcinoma (MCly colorectal)
What is the MC benign small bowel tumor?

What is the MC malignant small bowel tumor?
Benign: Leiomyoma. Same for uterine

Malignant: Adenocarcinoma
HYQ: what is the next step in the management of a pt that comes to the ER with severe ab pain and AXR shows free air in the abdomen?
Free air in ab= Perforation

immediate laprotomy
HYQ: A recent cuban immigrant with symptoms of malabsorption is found to have megaloblastic anemia.

What is the disease and what is the treatment?
Tropical Sprue

Folate, Abx (tetracycline, sulfa) for 3-6 mo
HYQ: what is the classic time frame for which post-op ileus resolves in the different parts of the gut?
Stomach: 48-72hr
Small Intestine: 24
Large Intestine: 3-5d
Elderly pt presents to the ER with vomiting and abdominal pain and distention. ABX shows two distinct but sequential portions of bowel in the sigmoid colon that are distended with air. What is the treatment?
Volvulus

Colonoscopy
Describe the diff signs that might be seen in appendicitis?
Psosas sign: Pain with passive hip extention
Obturator sign : Pain with passive internal rotation of flexed hip
Rovsings sign: RLQ on palpation of LLQ
Pain out of proportion to the abdominal exam is classic for what?
Acute Mesenteric Ischemia**
What characteristics ARE and which ARE NOT a/w IBS?
IBS: 12wks/yr, pain relieved with defication, a/w change in stool frequency or form

NOT IBS: sxs of malabsorption, wt loss or anorexia, progressively worsening pain, pain preventing sleep
What tumors (4) can cause a secretory diarrhea?
Carcinoid
VIPoma
Gastrinoma
Medullary thyroid CA
What is the most likely cause of malabsorption in a pt with a (+) sudan stain in the stool sample and normal D-xylose test?
Pancreatic Insuficiency

(+) sudan indicates steattorhea
(+) D-Xylose indicates that the intestinal villi are intact and can abs carbs
What is the TX for Whipple disease?
TMP-SMX or Ceftriaxone for at least 12-mo
What serum antibodies are seen in cases of celiac sprue?

What's the buzz phrase?
Anti-gliaden, Anti-endomycial

"blunting of the villi"
gluten intolerance
common in downs
dermatitis herpatiformis
What serum lab findings might help you distinguish Crohn's from UC?
(+)ASCA = chron's
(+) pANCA = UC
Jejunal biopsy shows Foamy macrophages on PAS
Whipple dz

TMP-SMX or Ceftriaxone for 12mo
QH: ____ is the MCC of acute diarrhea in children
Rotavirus
QH: 1/2 of pts with IBS have comorbid _____
Psychiatric Sxs, Depression, Anxiety
"Thumb Printing" and CT showing air within bowel wall and bowel wall thickining
Ichemic Colitis

More Common on the left, but sparing the rectum b/c of colorectal circulation
HLA-B27
PAIR

Psoriatic Arthritis
Ankylosing spondylitis
IBD
Reitter's syndrome
Treatment for Ileus?
NPO until bowel sounds return

Motility agents: Erythromycin, Neostigmine, Metoclopromide (reglan)
"Double Bubble" and "Birds Beak" on ABX
Volvulus

occurs in elderly and infants
H/P: Obstipation