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51 Cards in this Set

  • Front
  • Back

Hearing Frequencies

capable of hearing 20-20,000 Hz at birth


as you age, lose ability to hear very high and very low


outer ear provides most gain for frequencies between 2kHz- 5 kHz

Pinna

outer ear


captures sounds and directs it to the middle ear


made of fibrocartilage


attached to temporal bone by extrinsic muscles


concha, helix, antihelix, tragus, antitragus and ear lobe (CHATAL)

external auditory meatus

ear canal


an oval, s-shaped tube


outermost is cartilage, continuous with the cartilage of the pinna


along with pinna, frequency selective because of shape, 45 degrees

Tympanic Membrane

Middle ear (eardrum)


vibrates in response to acoustic energy


cone of light, annulus


3 layers: outer: thin layer continuous with the lining of the EAM


middle: fibrous layer


internal: continuous with the lining of the middle ear cavity

Annulus

thickened outer ring on tympanic membrane


attached to a groove in the tympanic cavity

Tympanic Cavity

Middle ear


where ossicles sit (malleus, incus, stapes)


air filled cavity within the petrous portion of the temporal bone


epitympanic recess: superior to the tympanic membrane, contains head of malleus and most of incus



Tympanic Cavity Landmarks

Superior wall: Tegmentum


Inferior wall: Jugular


Lateral wall: Membranous


Medial wall: Labyrinthine


Anterior wall: Carotid


Posterior wall: Mastoid

Ossicle

within tympanic cavity


transmits acoustic vibration from the TM to the inner ear


1. Malleus: largest, most lateral, suspended in the TC by 3 ligaments


2. incus: articulates laterally with the malleus and medially with the stapes, suspended by posterior ligament


3. stapes: smallest, footplate attached to the oval window

Middle Ear Muscles

Tensor Tympani


Stapedial Muscle


Actions: increases the stiffness of the ossicular chain, may provide some sound protectoin against low-frequency, intense sounds

Tensor Tympani

middle ear muscle


located along and above the eustachian tube


enters the TC


attached to the manubrium of the malleus


innervated by the branch of the mandibular nerve of the trigeminal

Stapedial Muscle

Middle ear muscle- stapedius


smallest muscle in the body


emerges from pyramid and inserts on the neck of the stapes


innervated by the stapedial branch of the facial nerve

Eustachian (Auditory) Tube

extends downwards, medially and forward from the tympanic cavity to the nasopharynx


normally closed to protect ear from pathogens


opens during swallowing and yawning


equalized pressure between the middle ear and external atmospheric pressure

Transduction

transforming one form of energy into another form of energy



Acoustic energy changes to mechanical energy at what point?

Tympanic membrane

Impedance

Obstruction


mismatch: air filled middle ear space and fluid filled ear space


sound going from air filled space to fluid filled: some is lost, sound becomes dampened


ossicles help move sound

Von Bekesy's Experiments

observed basilar membrane motion in human cadavers (dead), found broad tuning

traveling wave

always at base of cochlea and moves up, base to apex, base is narrower


amplitude changes as it moves along the length of the cochlea


the position along the basilar membrane at which its amplitude is highest depends on the frequency of the stimulus



Tuning Curve

sharp tuning curve: want this to be able to distinguish one frequency from another


200 Hz: Hz before, needs more intensity


and Hz after need more intensity, 200 needs less


broad tuning: very loud sounds, death


death of cells leads to poor frequency tuning of basilar membrane

Outer vs.Inner hair cells

outer: test tube shape


inner: tear drop shape


damage to outer hair cells lead to broad tuning



Active Mechanism

flow of energy enhances active mechanism


1. outer hair cell motivity: changes in length when different voltages applie


2. tip links

inner ear

2 labyrinthine systems


osseous outer labyrinth (bony)


membranous labyrinth (within bony labyrinth)

Osseous Labyrinth

composed of a series of ducts and cavities within the petrous portion of the temporal bone


contains: vestibuli (sits between cochlea and semicircular canals) , semicircular canals, coiled cochlea

Semicircular Canals

lateral-most portion of the bony labyrinth


superior, posterior, lateral canals


involved in balance and body orientation

coiled cochlea

medial-most portion of bony labyrinth


oval window is entrance


coiled around central core: modiolus


2 3/4 turn from base to apex



Membranous Cochlear Labyrinth

spiral-shaped


3 canals:


1. scala vestibuli: contains perilymph


2. scala media: lies between the scala vestibuli and scala tympani, contain the organ of court (endolymph fluid fills area)


3. scala tympani: contains perilymph

Reissner's Membrane

top


extends for the osseous spiral lamina to the outer bony wall


joins the basilar membrane at the helicotrema at the apex of the cochlea


divides scala vestibuli from the scala media

Basilar Membrane

bottom


helps discriminate among very soft sounds


formed at the osseous spiral lamina and extends out to the outer wall of the cochlea via the spiral ligament


divides the scala media from the scala tympani



Organ of Corti

in scala media, sits on top of basilar membrane


1. inner hair cells


2. outer hair cells


3. tectorial membrane


4. supporting cells

Inner hair cells

one row


approx. 3500 cells


stereocilia sits on top

outer hair cells

3 rows


approx. 12000 cells


stereocilia sits on top


`

tectorial membrane

sits over hair cells


gelatinous-like structure, tips of tallest rows of OHC come in contact

Recticular Lamina

holds the supporting cell in place at the top


tissue in-between hair cells and under stereocilia

What happens with the mechanical energy from the footplate of the stapes

it gets transduced into electrical energy at the organ of corti


high frequency sounds at base, low frequency sounds at apex


middle ear: mechanical energy


inner ear: electrical energy





Afferent Innervation

cochlea to brainstem(central nervous system)


30,000 neurons innervate the cochlea


part of auditory nerve (8) that convey info from the cochlea to the central auditory system


neural fibers branch off the hair cells and then travel to the spiral ganglion cells in the modiolous (very middle of cochlea)


long neural process from the cell body in the ganglion then travel to the cochlear nucleus

2 types of neural afferent fibers

inner radial (type 1) fibers: represent 90-95% of all afferent fibers, innervate inner hair cells (many fibers attached to one inner hair cell)


outer spiral fiber (type 2): synapse on multiple outer hair fibers, one to many innervation (one fiber to many fibers)

Efferent Auditory Pathway

brainstem to cochlea


from auditory neural pathway to hair cells


may enhance fine frequency tuning in the cochlea


not much known

Resting Potential

a neuron is not sending a signal


inside of the neuron is negative relative to the outside (-70mV)


higher concentration of Na+ located outside the cell compared to K+ inside the cell = inside negative


at rest= more negative


inside= potassium


outside= sodium

Depolarization

sodium ions moving into axons, inside becoming more positive


loss of positive ions from the outside of the cell


inside becomes positive


Na+ ions move into the cell


signal/ impulse is transmitted

Repolarization

once a specific positive charge is within the cell the positive ions (Na+) are moving outside the cell (reversal)


inside becoming more negative



Refactory Period

during repolarization


pause, flushing a toilet


absolute: cell cannot receive another neural impulse


Relative: call has repolarized sufficiently such that a strong neural impulse can lead to excitation

response to auditory nerve fibers

auditory nerve responds to input from hair cells


depolarizatoin --> neurotransmitter release --> AP in auditory nerve fibers

which neural fibers are connected?

inner radial


outer spiral

what info is the auditory nerve getting?

frequency, intensity, temporal (time)


Spontaneous Activity

neurons produce action potentials at random intervals without stimulation


when stimulus ends, regular activity begins



Tuning Curves

representations of how specific auditory neurons respond to different frequencies


lowest point= characteristic frequency


have steep high-frequency slope


extended low- frequency tail


narrow tip



Rate- level functions

representations of how an auditory nerve fiber response changes with changing stimulus level (intensity)


input/output functions



Histograms

representations of the response of auditory neurons over time (temporal)


don't necessarily get a response each time present a stimulus but you will get a pattern with repeated trials


pattern is plotted on PST histogram


plot showing number of spikes as function of time after stimulus presented

phase locking

auditory nerve responses "trace out" the time waveform of sound


only positive parts of time waveform are represented


signals up to 5000 Hz- best at 1000Hz



frequency coding

place= tuning cuves, along basilar membrane, higher frequencies- base, lower- apex


time= histograms


wide on graph= high level


time takes for 1 cycle= period


cochlea performs frequency analysis, see results in auditory nerve firing patterns


auditory nerve response is consisten with cochlear response

intensity coding

discriminate between 0 and 140 dB SPL


ratio of pressure changes is 10,000,000:1


spread of excitation along the basilar membrane may also be used to code intensity

dynamic range

point of increase, highest minus lowest


individual auditory nerve fibers cannot provide a code for intensity across the dynamic range of hearing