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40 Cards in this Set

  • Front
  • Back
Cardiac sarcoma
Diagnosis: osteosarcoma of the right atrium

Case findings:
Right atrial mass with irregular, multilobulated borders
Mass obstructs the IVC, thrombus throughout IVC
Inhomogeneous enhancement of the liver and non-enhancement of hepatic veins consistent with Budd-Chiari syndrome
DDX right atrial mass:
Angiosarcoma
Osteosarcoma (MC left-sided)
Myxoma
Lymphoma
Metastatic disease including metastatic osteosarcoma
Large adherent clot
Primary cardiac sarcoma:
Rare and < 25% of primary cardiac tumors
MC angiosarcoma (tend to be right-sided)

Additional subtypes: undifferentiated, fibrosarcoma, MFH, leiomyosarcoma, myxosarcoma, synovial sarcoma, neurofibrosarcoma, osteosarcoma
Congenital absence of left pericardium
Case findings:
Shift of the mediastinum toward the left side
Appearance of the heart is unusual  3 large convexities (aortic arch, main pulmonary artery, LV segment) at elongated left heart border
Hyperlucent area between the aortic arch and the main PA, due to interposition of lung tissue at this level (arrow)
MR:
Heart is rotated clockwise (horizontal position of the interventricular septum)
Absence of a hypointense line in the epicardial fat along the left heart border
Premature atrophy of left cardiac vein (left duct of Cuvier)
Leads to a loss of blood supply to the left pleuropericardial membrane (normally persists and forms the left pericardium)

Features:
Abrupt termination of the right pericardium or total absence of pericardium
Cardiac rotation
Shift to the left hemithorax
Interposition of lung between the aortic arch and MPA
Associated with other congenital cardiopulmonary abnormalities in 1/3rd of cases:
Atrial or ventricular septal defects
Persistent ductus arteriosus
Aortic valve anomalies
Tetralogy of Fallot
Bronchopulmonary sequestration
Left atrial appendage thrombus
Case findings:
Left atrial appendage is located between the LAD coronary artery and the upper part of the left atrium
Curved non-enhanced filling defect is seen inside the left appendage
US: fixed left atrial appendage thrombus

Left atrial thrombi MC occur in the setting of stagnant blood flow

Predisposing conditions:
Atrial fibrillation
MV disease, MV prostheses
Cardiomyopathy
Left atrial calcification
Case findings:
XR: heart is enlarged, thin oval curvilinear rim of calcification projected through the center of the heart
CT: LA wall calcification, MV is calcified

LA calcification: result of extensive chronic rheumatoid heart disease

Associated with:
Atrial fibrillation
Long standing congestive cardiac failure
Mural thrombus and embolization
LC chronic renal failure
Left atrial myxoma
Case findings:
CT: pedunculated bilobular mass within LA
US: mass within the anterior LA , and a 2nd LA mass extends through the MV into the LV

Primary cardiac neoplasms are rare, most are benign
MC in left atrium (75%)
DDX:
Because of fibrosis, calcification or iron, myxoma may be dark on GRE images, cine, mimicking the signal drop seen with thrombus
Lipoma: bright on T1 and darken with FS, MC in RA
Benign tumors are typically well circumscribed, whereas malignant tumors tend to be infiltrative, large, have a broad point of attachment, and are associated with pericardial effusion
Clinical presentations:
Obstructive symptoms: shortness of breath, orthopnea and PND
Embolization: peripheral embolization of tumor fragments
Systemic features: fatigue, fever, elevated ESR, hemolytic anemia

DDX:
Thrombus: MC sessile and of low echogenicity
In contrast with myxoma, which is echogenic, mobile, pedunculated and with a point of attachment at the fossa ovalis in most cases
Left ventricular thrombus
Case findings:
CT: apical myocardium is thin, with an intra-ventricular pedunculated mass suggesting an old infarct complicated by a thrombus
US: apical thrombus of in the left ventricle
Left ventricular aneurysm
Case findings:
Bulging of the left heart border with curvilinear peripheral calcification
Lateral CXR demonstrates the relatively anterior position of the calcification

Clinical: mitral regurgitation
Left ventricular aneurysm
Case findings:
Bulging of the left heart border with curvilinear peripheral calcification
Lateral CXR demonstrates the relatively anterior position of the calcification

Clinical: mitral regurgitation
Cor triatriatum (“heart with three atria”)
Case findings:
XR: Normal heart size with RV enlargement
MR: Membrane at the atrial level with high signal from slow flow

Rare congenital anomaly due to a failure of the common pulmonary vein to incorporat
Cor triatriatum (“heart with three atria”)
Case findings:
XR: Normal heart size with RV enlargement
MR: Membrane at the atrial level with high signal from slow flow

Rare congenital anomaly due to a failure of the common pulmonary vein to incorporate normally into left atrium
Posterior accessory chamber connects with the true left atrium  in an obstruction to the pulmonary venous return

Left atrium is pushed against the mitral valve
Small atrial appendage
Ebstein’s anomaly
Case findings:
Septal leaflet and inferior leaflet of the tricuspid valve are plastered to the right ventricular wall near the cardiac apex
Anterior leaflet of the tricuspid valve is present in the normal location at the atrioventricular groove
RA and atrialized portion of RV are markedly enlarged

Malformation of the tricuspid valve leaflets where one or more leaflets arise from the right ventricle wall (septal leaflet is always involved, and inferior leaflet is commonly involved)
Atrialized portion or inlet portion of RV:
RV proximal to the septal leaflet
Thin walled and poorly contractile
Functional portion of the RV remains trabeculated
Results in severe tricuspid insufficiency
DDX cyanosis with decreased vascularity:
Tetralogy of Fallot
Truncus arteriosus (type IV)
Tricuspid atresia (*)
TGV (*)
Ebstein’s anomaly
(*) Also in DDX cyanosis with increased vascularity
TAPVR
Diagnosis: TAPVR, supracardiac (type 1)

DDX cyanosis with increased vascularity:
Truncus arteriosus (type I, II, III)
TAPVR
Single ventricle
Tricuspid atresia (*)
TGV (*)

(*) Also in DDX cyanosis with decreased vascularity
TAPVR
Diagnosis: TAPVR, supracardiac (type 1)

DDX cyanosis with increased vascularity:
Truncus arteriosus (type I, II, III)
TAPVR
Single ventricle
Tricuspid atresia (*)
TGV (*)

(*) Also in DDX cyanosis with decreased vascularity
Viral myorcarditis
DDX cardiomegaly with normal vascularity:
Viral myocarditis
Endocardial fibroelastosis
Aberrant left coronary artery
Cystic medial necrosis
Diabetic mother
Hypoplastic left heart syndrome
DDX CHF in newborn (impede return of flow to left heart):
Infantile coarctation
Congenital aortic stenosis
Hypoplastic left heart syndrome
Cor triatriatum
TAPVR, infracardiac (type 3)
Atrial septal defect (ASD)
Case findings:
RA is slightly dilated
RV, LV, LA are normal in size
L-R shunt at atrial level

Types:
Ostium secundum: MC (60-70%), large defect of 1-3cm in the region of the fossa ovalis
Ostium primum (30%): associated
Atrial septal defect (ASD)
Case findings:
RA is slightly dilated
RV, LV, LA are normal in size
L-R shunt at atrial level

Types:
Ostium secundum: MC (60-70%), large defect of 1-3cm in the region of the fossa ovalis
Ostium primum (30%): associated with an ECD
Sinus venosus (5%): defect of the superior inlet portion of the atrial septum

ASD primum with PAH

Atrial septal defect (ostium secundum)
Ventricular septal defect (VSD)
Membranous/perimembranous (80% of VSD)
Defect is below the crista supraventricularis of the RV and 1 cm caudal to the base of the aorta 
Muscular (10% VSD)
Tend to be small and multiple 
Supracristal or outlet VSD (5%
Ventricular septal defect (VSD)
Membranous/perimembranous (80% of VSD)
Defect is below the crista supraventricularis of the RV and 1 cm caudal to the base of the aorta
Muscular (10% VSD)
Tend to be small and multiple
Supracristal or outlet VSD (5% of VSD)
Located beneath pulmonary valve with upper border of the defect beneath right coronary cusp of the aortic valve in the LV
MR: defect in the muscular ring at the level of the pulmonary valve in the right ventricular outflow tract
Inlet or atrioventricular canal (5% of VSD)
Represents a component of atrioventricular septal defect along with an ostium primum ASD and common atrioventricular valve
Associated with trisomy 21

VSD, membranous
VSD, supracristal
Patent ductus arteriosus (PDA)
Case findings:
MR: aorta focally dilated at site of ductal attachment, consistent with an aortic spindle

PDA: persistence of the distal aspect of the primitive 6th aortic arch
MC in premature infants, females, and in individuals living at high altitudes
Prostaglandins maintain patency, whereas prostaglandin inhibitors (indomethacin) cause its closure

Features:
Aortic spindle (His’ spindle): dilated part of aorta just below the isthmus
Large aortic arch
Dilated left atrium
Marfan’s syndrome
Case findings:
Aortic root aneurysm including enlargement of the sinuses of Valsalva
Aortic caliber is normal distal to the sinotubular junction

Marfan’s syndrome:
Annuloaortic ectasia (complication of aortic regurgitation)
Down’s syndrome
Atrioventricular canal (endocardial cushion defect)
William’s syndrome
Supravalvular aortic stenosis, idiopathic hypercalcemia, elfin facies
Neurofibromatosis
Coarctation of the descending aorta
Tetralogy of Fallot
Components of tetralogy of Fallot:
Pulmonic stenosis
Result of infundibular musculature hypertrophy (above crista supraventricularis and below pulmonary valve)
VSD
Overriding aorta
Right ventricular hypertrophy

Pulmonary atres
Tetralogy of Fallot
Components of tetralogy of Fallot:
Pulmonic stenosis
Result of infundibular musculature hypertrophy (above crista supraventricularis and below pulmonary valve)
VSD
Overriding aorta
Right ventricular hypertrophy

Pulmonary atresia with VSD:
Variant of tetralogy of Fallot
Instead of pulmonary stenosis, pulmonary artery is atretic
Pulmonary blood flow is derived from the aorta through PDA
Pulmonary artery is present, although hypoplastic
Truncus arteriosus
Single trunk arising from right and left ventricles, aligned over a VSD
Type I: main pulmonary artery arises from truncus
Type II and type III: individual right and left pulmonary arteries arise from truncus

Rastelli conduit:
Tre
Truncus arteriosus
Single trunk arising from right and left ventricles, aligned over a VSD
Type I: main pulmonary artery arises from truncus
Type II and type III: individual right and left pulmonary arteries arise from truncus

Rastelli conduit:
Treatment for truncus arteriosus, pulmonary atresia
Right ventricle to pulmonary artery

DDX:
Pulmonary atresia: small infundibular chamber that is not seen in truncus

Truncus arteriosus (type 1)
Hypertrophic cardiomyopathy
Case findings:
Severely hypertrophied RV and narrowing of the right ventricular outflow tract
Hypertrophied LV with near-obliteration of the left ventricular cavity
Left ventricular hypertrophy without chamber enlargement
Variants:
MC diffuse hypertrophy of the ventricular septum and the anterolateral free wall (70%)
Basal septal hypertrophy (10%-15%)
Concentric hypertrophy (5%)
Apical hypertrophy (< 5%)
Posterolateral wall hypertrophy (1%)

DDX: septal tumor (enhances with Gd)
Congestive heart failure
Case findings:
Cardiomegaly
Interstitial edema
Increased central markings
TAPVR, infracardiac
Case findings:
Normal size heart
Congestive heart failure
Aortic coarctation
Congenital stenosis of proximal descending aorta at the isthmus
Associated
Aortic bicuspid valve (50%)
VSD, aortic stenosis, MV abnormalities, PDA

Velocity-encoded cine images are taken at a level below the coarctation and at the level of the diaphragm
Used to measure blood flow during a cardiac cycle to determine the presence and degree of collateral flow around the coarctation
Collateral flow would indicate hemodynamic significance

DDX:
Pseudocoarcation: normal gradient pressure across area of narrowing
Takayasu’s arteritis: lower thoracic and abdominal aortic stenosis
Aortic coarctation
Congenital stenosis of proximal descending aorta at the isthmus
Associated
Aortic bicuspid valve (50%)
VSD, aortic stenosis, MV abnormalities, PDA

Velocity-encoded cine images are taken at a level below the coarctation and at the level of the diaphragm
Used to measure blood flow during a cardiac cycle to determine the presence and degree of collateral flow around the coarctation
Collateral flow would indicate hemodynamic significance

DDX:
Pseudocoarcation: normal gradient pressure across area of narrowing
Takayasu’s arteritis: lower thoracic and abdominal aortic stenosis
Pulmonary sling
Case findings:
Esophogram: posterior indentation on trachea and anterior indentation on esophagus  left pulmonary artery passes between trachea and esophagus
MR: origin of left pulmonary artery from the right pulmonary artery

Pulmon
Pulmonary sling
Case findings:
Esophogram: posterior indentation on trachea and anterior indentation on esophagus  left pulmonary artery passes between trachea and esophagus
MR: origin of left pulmonary artery from the right pulmonary artery

Pulmonary artery sling may compress the right main stem bronchus or bronchus intermedius
Left pulmonary artery is smaller with less flow
Associated with:
Complete cartilage rings which may cause a long segment tracheal stenosis
Tracheal bronchus

Left aortic arch, normal branching
Left aortic arch, aberrant RSA

Right aortic arch
Right aortic arch with aberrant LSA (MC)
Kommerell diverticulum and left-sided ligamentum arteriosum form a vascular ring
Mirror-image right aortic arch (2nd MC)
Associated with CHD (95%): MC tetralogy of Fallot or truncus arteriosus
Right aortic arch with isolated LSA (rare)

Esophogram: posterior indentation on esophagus from the aberrant LSA at the level of the aortic arch

Right aortic arch, aberrant LSA
Right aortic arch, mirror image branching

Double aortic arch
True vascular ring
MC right arch is dominant (80%)
Dominant arch is MC posteriorly located arch and cranial

Left arch MC located anteriorly and right arch posteriorly
Descending aorta is MC left-sided

Cardiac surgical procedures
Glenn:
SVC to right pulmonary artery
Rastelli: truncus arteriosus, pulmonary (artery) atresia
Right ventricle to pulmonary artery
Fontan: pulmonary atresia
Right atrium to pulmonary artery

Blalock-Taussig shunt: tetralogy of Fallot
subclavian artery to pulmonary artery
TGV
Jatene: arterial switch
Mustard/Senning: atrial baffle
Tricuspid atresia
Fontan and Glenn procedures to bypass the RV
Scimitar syndrome
Components of scimitar syndrome:
PAPVR (infracardiac) from the right lung to the IVC
Hypoplasia of right lung with dextroposition of heart;
Hypoplasia of right pulmonary artery
Systemic arterial supply of the right lower lobe from the abdominal aorta

Not all components need to be present
Aortic insufficiency
Case findings:
Flow jet emanating from the aortic root into the left ventricle represents aortic regurgitation
No flow jet into aortic root to suggest aortic stenosis
Transposition of great vessels (TGV)
Case findings:
MR: aorta is anterior right of pulmonary artery

Complete TGV:
Cardiac chambers are in normal position
Connection between left and right heart (VSD, ASD) necessary for life
Congenitally corrected
Transposition of great vessels (TGV)
Case findings:
MR: aorta is anterior right of pulmonary artery

Complete TGV:
Cardiac chambers are in normal position
Connection between left and right heart (VSD, ASD) necessary for life
Congenitally corrected transposition
Cardiac chambers are also switched (compatible with life)
Aorta is located on the left and arises from RV
RV lies posterior and to the left of the LV
Anatomic right ventricle
Triangular configuration
Muscular band around the outflow tract
Coarse trabecular pattern of the apical septum
Moderator band at its apex
Arteriovenous valve and semilunar valve separated by muscle

Jatene (arterial switch): pulmonary artery straddles aorta on axial images
Mustard/Senning: atrial baffle

Jatene (arterial switch) for TGV
Tricuspid atresia
Case findings:
Solid bar of fat and muscle between dilated RA and hypoplastic RV
Large secundum-type ASD
RV outflow tract stenosis, infundibular stenosis (not shown)

Tricuspid valve and inflow portion of RV are absent
Hypoplastic RV consists of conus portion, which appears as an outpouching of LV
Associated with ventricular septal defect, pulmonary stenosis, and pulmonary atresia
Classified by associated cardiac anomalies:
Normally related great arteries (70%)
TGV (25%)
Corrected TGV (5%)

Treated with Fontan and Glenn procedures to bypass the RV
PAPVR
Case findings:
MIP: drainage of the right upper lobe pulmonary vein into SVC

Types:
Supracardiac: draining into SVC, brachiocephalic vein, or azygous vein
Cardiac: draining into RA or coronary sinus
Infracardiac: draining into IVC
Called sc
PAPVR
Case findings:
MIP: drainage of the right upper lobe pulmonary vein into SVC

Types:
Supracardiac: draining into SVC, brachiocephalic vein, or azygous vein
Cardiac: draining into RA or coronary sinus
Infracardiac: draining into IVC
Called scimitar syndrome
Associated with hypogenetic right lung

MC is right upper pulmonary vein draining into SVC
Associated with sinus venosus ASD

PAPVR (supracardiac)
Left upper lobe pulmonary vein (arrow) into a left vertical vein, which drains into the left brachiocephalic vein
Polysplenia syndrome
Case findings:
XR:
Ambiguous position of the liver
Dextroposition of the heart
MR:
Situs ambiguous with the liver on both the right and left side
At least two small spleens
Stomach is on the right
Persistent left SVC drains into the pulmonary venous atrium
Not shown:
Interruption of the IVC with azygous continuation
Aorta and pulmonary artery arise from a common single ventricle
Bilateral pulmonary arteries are seen passing over bilateral bronchi consistent with bilateral left-sidedness
Bilateral left-sidedness with bilateral hyparterial bronchi
Situs ambiguous, multiple small spleens

Cardiac manifestations:
Interruption of the IVC with azygous continuation (70%)
Persistent left SVC (50%)
Partial or total anomalous pulmonary venous connection (50%)
Atrial septal defect (80%)
Ventricular septal defect (70%)
Single ventricle (5%)
Malposition of the great arteries (30%)
Pericardial hematoma
Case findings:
Mass in the left atrioventricular groove, compressing the LA and LV
Acute angle of pericardial interface with the mass, indicating an intrapericardial location 
Signal is intermediate T1, without enhancement
Not sh
Pericardial hematoma
Case findings:
Mass in the left atrioventricular groove, compressing the LA and LV
Acute angle of pericardial interface with the mass, indicating an intrapericardial location
Signal is intermediate T1, without enhancement
Not shown:
Dark foci internally and dark rim on GRE images (central and peripheral calcifications)
Low T2
DDX pericardial mass:
MC pericardial hematoma
Pseudoaneurysm
Pericardial cyst
Low T1, homogeneous high T2, no enhancement
Neoplasm
Lymphoma
Case findings:
Mediastinal mass that encases the distal trachea and bilateral mainstem bronchi 
Mass invades the roof of the left atrium 
Enhances homogeneously

DDX:
Thrombus
Thrombus is darker on GRE sequences than muscle 
Tumor on GRE
Lymphoma
Case findings:
Mediastinal mass that encases the distal trachea and bilateral mainstem bronchi
Mass invades the roof of the left atrium
Enhances homogeneously

DDX:
Thrombus
Thrombus is darker on GRE sequences than muscle
Tumor on GRE cine images is similar to, or higher than, the myocardium
Tumor enhances with gadolinium, whereas clot does not
Angiosarcoma
MC primary cardiac tumor (MC in RA)
Unlikely to be centered around the carina
Fibrosing mediastinitis: should not invade the heart
Metastasis: MC small cell carcinoma of the lung

Lymphoma (different patient)
Atrial lipoma
Case findings:
Homogeneously high T2 mass in LA
Mass intrinsically bright on T1 (not shown), and does not enhance after gadolinium
SI of mass homogeneously reduced with FS

MC benign primary tumor of the heart
MC in RA (this case was a LA lipoma)
Angiosarcoma
Case findings:
Focally enlarged and lobulated interventricular septum mass
Mass demonstrates enhancement
DDX of thickened interventricular septum:
Asymmetric hypertrophic cardiomyopathy

MC malignant primary intracardiac tumor
Other primary malignant tumors:
Rhabdomyosarcoma
Leiomyosarcoma
Liposarcoma
Lymphoma
Pericardial cyst
Case findings:
Cystic mass conforming to the contour of the heart and the main pulmonary artery
Low T1, high T2, no enhancement
Benign developmental lesion formed when part of the embryonic percardium is pinched off
MC found in the right anterior cardiophrenic angle behind the right atrium

DDX of benign mediastinal cyst:
Bronchogenic cyst
Thymic cyst
Pericardial cyst: cyst conforms to the contour of other mediastinal structures
Constrictive pericarditis
Case findings:
Pericardium is thickened over the RA and TV
Pericardium is clearly identified between two layers of fat (pericardial fat and epicardial/subpericardial fat)

Etiology:
Cardiac surgery, radiation therapy
Tuber
Constrictive pericarditis
Case findings:
Pericardium is thickened over the RA and TV
Pericardium is clearly identified between two layers of fat (pericardial fat and epicardial/subpericardial fat)

Etiology:
Cardiac surgery, radiation therapy
Tuberculosis, post-viral pericarditis
Collagen vascular disease
Infiltration of the pericardium by neoplasm
Clinically difficult to differentiate between constrictive pericarditis and restrictive cardiomyopathy
Patients with constrictive pericarditis may benefit from pericardiodectomy whereas those with restrictive cardiomyopathy would not
Restrictive cardiomyopathy
Pericardium is of normal thickness (< 2 mm)
Constrictive pericarditis
Pericardium is > 4 mm thick

DDX thickened pericardium (use clinical history to help diagnose)
Constrictive pericarditis
After cardiac surgery
Uremic pericarditis
Pericardial effusion
Tuberculous pericarditis
Uncommon cause of pericarditis

Features:
Thickening of the pericardium and/or pericardial effusion
Enhancement of the pericardium seen in tuberculous pericarditis and may be due to granulation tissue in the pericardium
Ventricular aneurysm
Case findings:
Pericardial effusion with high T1 (serosanguinous)
Left ventricular true aneurysm 

True ventricular aneurysm
Large segment of nonviable myocardium
Focal wall thinning and is deformed during diastole and dilates
Ventricular aneurysm
Case findings:
Pericardial effusion with high T1 (serosanguinous)
Left ventricular true aneurysm

True ventricular aneurysm
Large segment of nonviable myocardium
Focal wall thinning and is deformed during diastole and dilates during systole
MC located in the anterolateral and apical aspect of LV, wide ostium

False ventricular aneurysm
Cavity that communicates with ventricular lumen, but not formed by myocardium
Results from a contained rupture of LV after myocardial infarction
MC in posterior and diaphragmatic aspect of LV, narrow ostium

False ventricular aneurysm
Arrhythmogenic right ventricular dysplasia (ARVD)
Case findings:
High T1 in myocardium of RV anterior free wall, corresponding to fatty infiltration
NB: signal from the posterior portion of the heart was suppressed with a posterior saturation band to reduce artifact

Right ventricular dysplasia
Results from replacement RV myocardium with fat or LC fibrous tissue
Results in right ventricular arrhythmias, which may be provoked by exercise and complicated by syncope or sudden cardiovascular collapse
MC men at a young or middle age

DDX:
Right ventricular outflow tract tachycardia (no evident structural abnormality)