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81 Cards in this Set

  • Front
  • Back

___________ occurs when an extra-cellular signaling molecule activates a cell surface receptor (i.e. estrogen molecules, phthalates,, etc.) In turn, this receptor alters intracellular molecules creating a response.

Signal transduction

A ________ is an ion or molecule that binds its receptor through a number of specific weak non-covalent bonds by fitting into a specific binding site or pocket.

ligand

G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are examples or _______________ proteins.

transmembrane

___________ is the durable, energy-consuming process by which a cell directs the contents of secretory vesicles out of the cell membreane and into the extracellular space.

exocytosis

___________ is an energy-using process by which cells absorb molecules (such as proteins) by engulfing them. It is used by all cells of the body because most substances important to them are large polar molecules that cannot pass through the hydrophobic plasma or cell membrane.

phagocytosis

_______________ endocytosis is a process by which cells internalize molecules (endocytosis) by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.

receptor-mediated

the overall reaction for aerobic respiration of glucose is summarized as _______________________________.

glucose + 6 O2 ---> 6 CO2 + 6 H20 + 32 ATP

ATP stands for __________________, which releases a great deal of energy when a _______________ group is removed, converting it into ADP.

adenosine triphosphate



phosphate

oxidative phosphorylation takes place in the inner membrane of the __________________.

mitochondria

cellular respiration produces _______ molecules of ATP for every one molecule of glucose.

32


plants store excess carbs in the form of a polysaccharide called ____________.

starch


animals store excess carbs in the form of a polysaccharide called ____________.

glycogen

________ ___________ is the process that joins monosaccharides together to form disaccharides.

dehydration reaction

the major carb used in plant cell walls is called __________, which is formed from alternating alpha 1-4 and beta 1-4 likages

cellulose

What are the 3 main components of an amino acid?

Carboxyl group


R group


amino group


Hydrogen atom

__________ is a disaccharide that consists of glucose and fructose.

sucrose

In animals, excess glucose is stored in the __________ as glycogen.

liver

__________ is the most abundant carb found on Earth and cannot be broken down by animals.

cellulose

how many carbon, hydrogen, and oxygen atoms make up one glucose molecule?

C6H12O6

____________ is a disaccharide formed from two glucose molecules via ______________ reaction.

maltose



dehydration

The building blocks of a protein molecule are bonded together by ____________ bonds. The process that joins these building blocks together is called ______________ synthesis (joined by dehydration reaction.

peptide



protein

an enzyme is a ______________ that speeds up chemical reactions.

catalyst/protein

The ______________ is the part of an enzyme where a substrate binds, leading to the formation of product (referred to as "lock and key" mechanism.)

active site



substrate

a nucleotide is composed of a _________________, _________________, and ________________ .

5-carbon sugar



phosphate group



nitrogenous base

degenerative diseases such as mad cow disease, Alzheimer's, and front temporal dementia may all be caused by malfunctions in protein ___________.

folding

a ___________ is a molecule with a shape that will allow it to bind to an enzyme, thus decreasing its enzymatic activity (like Antabuse)

competitive inhibitor

sickle-cell disease is caused when the 6th amino acid of beta-hemoglobin called glutamate is replaced by ___________. Why does this timy mutation cause sickle-cell anemia? Hydrophobic interactions between sickle-cell hemoglobin proteins lead to their aggregation into a fiber.

valine

If a DNA sequence of nitrogenous bases is 3' -GATTCTGC 5', the complementary mRNA sequence of nitrogenous bases would be _____________.

GCAGAAUC

The "central dogma" of biology states that information flow in the cell is unidirectional, from _______ to _______ to ________.

DNA



RNA



proteins

DNA has a unique ______________ shaped structure with a backbone of alternating ________ and ______________ molecules.

double-helix



sugar



phosphate

most life on Earth depends, directly or indirectly, on a process that combines water and carbon dioxide to make carbon-based compounds. This process is called _________________.

photosynthesis

what organic molecules have a chemical formula that is (or is very nearly) a multiple of (CH2O)?

carbohydrates

the linkage commonly found between subunits in a chain of monosaccharides is called a __________ bond.

glycosidic

animal cells commonly have polysaccharides attached to __________ in their surface membranes.

proteins and lipids

suppose that an equal amount of each of the following polysaccharides was placed in a landfill. Which of them should last the longest before it is decomposed?

cellulose

in many animals, this polysaccharide is found in large quantities in liver and muscle cells. It is highly branched with many alpha(1-4) and alpha(1-6) linkages.

glycogen

Although they have diversity of structures, all members of this group of organic molecules are primarily non-polar and thus water-insoluble

lipids

which of these are the main structural components of biological membranes?

phospholipids

testosterone is a substance that has important regulatory functions in humans and many other animals. Molecules with regulatory functions like testosterone are called _________.

hormones

the linkages commonly found between amino acids in a chain of amino acids is called a ___________ bond.

peptide

the unique sequence of the monomer sub-units in a protein is the _________ structure of the protein.

primary

the _________ structure of a protein refers to the conformation, or overall 3-D shape of a polypeptide that has been folded into a functional protein.

tertiary

excessive heat or extremes of pH often cause denaturation of proteins which means that the proteins __________________________.

are no longer in a functional 3-D structure.

chaperonins assist with ____________.

protein folding

nucleotides are joined together to make a nucleic acid strand by ______________ bonds.

phosphodiester

consider the DNA sequence 5' GATTACA 3'. If the strand with this sequence forms a double helix with another DNA strand, the sequence on the other stand should be a 5' _______________ 3'.

TGTAATC

RNA molecules are usually found as _____________.

a single strand with some folds and twists where the strand bonds with itself to make some double-helical regions

Alzheimer's disease, sickle-cell anemia, and mad cow disease are all examples of diseases caused by _______________.

protein misfolding.

Which of the following types of molecules are the most diverse in terms of structure and types of roles in cells?

proteins

you modify the primary sequence of an enzyme in a region that will be the active site when the protein is properly folded. What is the predicted outcome of this change?

the enzymes will not properly bind to the substrate.

chromatin consists of ___________.

nucleosomal strands

nucleoli are found within the nucleus and participate in the synthesis of ____________.

rRNA

The _____________ is involved in the synthesis of lipids.

smooth ER

The Golgi complex ____________.

receives proteins made in the rough ER and chemically modifies them.

The ________________ contains hydrolytic enzymes for the digestion of proteins, lipids, nucleic acids, and ploysaccharides. It is frequently referred to as the garbage disposal of the cell.

lysosome

cellular respiration is the process by which __________ and ___________are converted to H20 and CO2 during the formation of cellular energy.

O2 and C6H12O6

Many scientists subscribe to the endosymbiotic theory, It states that mitochondria may have originates from ancient independent living bacteria. The reason provided is that _________.

both have similar components for protein synthesis.

select the correct path of protein synthesized on a ribosome attached to the rough ER would follow in the endomembrane system.

rough er --> Golgi complex --> vesicle --> plasma membrane

The following is composed of microtubules except:


intermediate filament


centriole


miotic spindle


flagellum


cytoskeleton

intermediate filament

membrane sterols such as cholesterol function in animal cell membranes to ____________.

maintain membrane fluidity and shape

according to the fluid mosaic model of cell membranes, the fluid part of the model refers to ____________.

the phospholipid molecules which vibrate, spin, and exchange places within the same layer of the bilayer

movelent of a substance from an area of low concentration to an area of high concentration using energy obtained from ATP is called __________

active transport

carrier proteins are often used by the cell to transport __________.

glucose and amino acids

aquaporins are ____________.

specific channels for water transport

signal proteins bind to ___________ generating a large cascade of reactions which results in the activation of specific gemes.

membrane surface receptors

aerobic cellular respiration occurs in the __________.

mitochondria

the interior surface area of a mitochondria is greatly increased by __________.

cristae

this unbranched chain consisting of alpha and beta glucose subunits is the primary structural fiber in plant cell walls .

cellulose

parts of the enzyme molecule that bind with a substrate are called ___________.

active sites

_________ provide a "fingerprint" for the cell so that it can be recognized by other cells

glycoproteins

dietary proteins _____________.

are considered "complete" only if they contain the 8 essential amino acids

soda, with a pH of 3 is ___________ more acidic than a glass of water with a pH of 7.

10,000

Which of the following is primarily responsible for the movement or organelles and chromosomes within the cell?

microtubules

hydrogenation is the artificial addition of ____________ to a/an _____________. This can improve a food's taste, texture, and shelf life.

hydrogen



unsaturated fat

multiple simple carbohydrates are linked together into more complex ones. Complex carbohydrates include ____________ which is the primary source of energy storage in animals.

glycogen

in general, molecules made mostly of carbon atoms covalently bound to each other and to other atoms are called ________.

organic molecules

which of the following is NOT a major function of proteins in living organisms?


speeding up biological reactions


transporting substances across membranes


providing structural support


regulation the activity of other cellular molecules


storing genetic information

storing genetic info

proteins are polymers of __________.

amino acids

which one of the following cellular components is NOT directly involved in synthesis or secretion of molecules in the cell?


ribosomes


lysosomes


rough ER


golgi complex


smooth ER

lysosomes

cytoskeletal elements are assembled from ________.

proteins

chloroplasts are the site of ____________.

photosynthesis