Nocardia, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Bacillus * Mycobacterium tuberculosis has prediliction for apices of teh lung

Closteridium, bacteroides, actinomyces Lack catalase and/or superoxide dismutase and thus are susceptible to oxidative damage. Foul-smelling, difficult to culture, produce gas in tissue

Why are aminoglycosides ineffective against anaerobes?

Require O2 to enter bacterial cell

Intracellular bugs: obligate, facultative

Obligate - Rickettsia, chlamydia Facultative - mycobacterium, brucella, francisella, listeria, yersinia, legionella, salmonella

Examples of encapsulated bacteria

Streptococcus pneumoniae, haemophilus influenza, neisseria minigitidis, klebsiella pneumoniae

How to tell if encapsulated bug is present?

Quellung reaction - if encapsulated bug is present, capsule sweels when specific anticapsular antisera are added

What is the virulence factor of staph aureus?

Protein A, binds Fc-IgG, inhibits complement fixation and phagocytosis

What is the classic triad in rickettsiae?

Headache, fever, rash (fasculitis).

What are the vectors for different rickettsial diseases?

Rocky mountain spotted fever (tick) - rickettsia ricketsii Endemic typhus (fleas) - R. typhi Epidemic typhus (human body louse) - R. prowazekii Q fever (inhaled aerosols) - Q feveri

What is so unusual about Q fever?

Q fever is different bc has no rash, no vector, has negatie Weil-Felix, causative agent survives for a long time outside and does not have rickettsia as genus name.

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Bacteriology: First Aid

Bacteriology: First Aid

by cliu009, Oct. 2007

Subjects: bacteriology first-aid

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Obligate Aerobes	Nocardia, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Bacillus * Mycobacterium tuberculosis has prediliction for apices of teh lung	Nagging Pests Must Breathe
Obligate Anaerobes	Closteridium, bacteroides, actinomyces Lack catalase and/or superoxide dismutase and thus are susceptible to oxidative damage. Foul-smelling, difficult to culture, produce gas in tissue	Found in GI tract
Why are aminoglycosides ineffective against anaerobes?	Require O2 to enter bacterial cell
Intracellular bugs: obligate, facultative	Obligate - Rickettsia, chlamydia Facultative - mycobacterium, brucella, francisella, listeria, yersinia, legionella, salmonella	Stay inside when it's Really Cold
Examples of encapsulated bacteria	Streptococcus pneumoniae, haemophilus influenza, neisseria minigitidis, klebsiella pneumoniae
How to tell if encapsulated bug is present?	Quellung reaction - if encapsulated bug is present, capsule sweels when specific anticapsular antisera are added
What is the virulence factor of staph aureus?	Protein A, binds Fc-IgG, inhibits complement fixation and phagocytosis
What is the classic triad in rickettsiae?	Headache, fever, rash (fasculitis).
What is the treatment of choice for most rickettsial infections?	Tetracycline
What are the vectors for different rickettsial diseases?	Rocky mountain spotted fever (tick) - rickettsia ricketsii Endemic typhus (fleas) - R. typhi Epidemic typhus (human body louse) - R. prowazekii Q fever (inhaled aerosols) - Q feveri
What is so unusual about Q fever?	Q fever is different bc has no rash, no vector, has negatie Weil-Felix, causative agent survives for a long time outside and does not have rickettsia as genus name.