Bacterial Infections Of The Skin Ii

Front 1

What are the ssx of ecthyma gangrenous?

Back 1

1. Vesicle--> hemorrhagic pustule--> necrotic ulcer

2. Must assume pseudomonas sepsis

Front 2

How do you tx ecthyma gangrenosum?

Back 2

1. Aminoglycoside + Piperacillin

Front 3

What are the MCC of toe-web infection?

Back 3

1. Proteus

2. E. coli

3. Pseudomonas

Front 4

What is the MCC of green nail syndrome?

Back 4

1. Pseudomonas

2. Seen in people who chronically have their hands in water

Front 5

How do you tx green nail syndrome?

Back 5

1. Benzoyl peroxide

2. Acetic acid soak

Front 6

What are the ssx of hot tub folliculitis?

Back 6

1. 1-4 days after exposure

2. Follicular pustules

Front 7

What is the risk of hot tub folliculitis?

Back 7

1. Malignant external otitis

Front 8

What is the MCC of hot tub folliculitis?

Back 8

1. Pseudomonas

Front 9

How do you tx hot tub folliculitis?

Back 9

1. Cipro

Front 10

What are the ssx of meningococcemia?

Back 10

1. Hemorrhagic macules on palms and soles

2. Flu-like ssx

3. Angular infarcts with erythematous rim and gun-metal gray interior

Front 11

What are the major categories of TB?

Back 11

1. Exogenous

2. Endogenous

3. Hematogenous

4. Tuberculids

Front 12

Back 12

1. Positive PPD

Front 13

What are the ssx of primary inoculation TB?

Back 13

1. Occurs at inoculation site of TB-free person

2. Tuberculous chancre

3. Regional LAD

Front 14

What are the ssx of TB verrucosa cutis?

Back 14

1. Exogenous inoculation---- Prosector's wart

2. Usually on doors of hands and fingers, buttocks, and ankles

Front 15

What are the ssx of scrofuloderma?

Back 15

1. Direct extension to skin from underlying tuberculous lymphadenitis

2. Occurs over cervical lymph node,s bone, and joints

Front 16

What are the ssx of TB cutis orificialis?

Back 16

1. Occurs at mucocutaneous borders of nose, mouth, tongue, anus, urinary meatus, and vagina

2. Autoinoculation from underlying active TB

3. Non-healing ulcer

Front 17

What are the ssx of lupus vulgarism?

Back 17

1. Hematogenous TB

2. Distant metastasis

3. Apple-jelly color when blanched

4. MC in head and neck region

Front 18

What are the ssx of military TB?

Back 18

1. Fulminant TB of lungs or meninges

2. MC in AIDS patients

Front 19

What are the ssx of metastatic TB abscess?

Back 19

1. Hematogenous spread

2. Firm, non0-tneder erythematous nodules

3. Chronic mastitis with abscess and sinus formation

Front 20

How do you tx TB?

Back 20

1. RIPE

2. Multidrug chemotx

3. Surgical excision

Front 21

What is the MCC of mycobacterial infection of skin in the US?

Back 21

1. M. marinum

Front 22

What is the MCC of swimming pool granuloma?

Back 22

1. M. marinum

Front 23

What are the ssx of swimming pool granuloma?

Back 23

1. Small papule with sporotrichoid pattern spread

2. Synovitis

3. Draining sinuses

Front 24

How do you tx swimming pool granuloma?

Back 24

1. Excision

2. Minocycline

Front 25

What is the MCC of buruli ulcer?

Back 25

1. M. ulcerans

Front 26

What are the ssx of buruli ulcer?

Back 26

1. Solitary hard painless subQ nodule that ulcerates and becomes undermined

Front 27

How do you tx buruli ulcer?

Back 27

1. Excision

2. Rifampin and amikacin or ethambutol with bacterium

Front 28

How do you dx Hansen's disease?

Back 28

1. Fite Faraco stain

2. Slit smears of skin and stain

3. Found in smear---- multibacillary

4. Negative skin and smear--- paucibacillary

Front 29

What is the difference between paucibacillary and multibacillary leprosy?

Back 29

1. Paucibacillary-- strong cell-mediated response (tuberculoid)

2. Multibacillary-- inadequate response (lepromatous)

Front 30

What is the MC primary clinical manifestation of leprosy?

Back 30

1. Numbness in cool areas of body

2. Solitary, ill-defined hypo pigmented macule

Front 31

What are the ssx of tuberculoid leprosy?

Back 31

1. Hypopigmented or erythematous

2. Hairless, dry

3. Saucer right side up lesion

4. Face, limbs, and trunk

Front 32

What is the nerve involvement of tuberculoid leprosy?

Back 32

1. Proximal peripheral nerves enlarged--- greater auricular, superficial peroneal

Front 33

What are the ssx of borderline lepromatous leprosy?

Back 33

1. Symmetrical numerous lesions--- too many to count

2. Small lesions outnumber larger borderline like lesions

3. Later nerve involvement

Front 34

What are the ssx of lepromatous leprosy?

Back 34

1. No change in skin texture

2. Pale lepromatous macule with numerous bacilli in lesions

3. Small and numerous lepromatous macules

4. No loss of sensation over lesions

5. Hair loss of later 1/3 of eyebrows

Front 35

Back 35

Lepromatous leprosy:

Leonine facies, madarosis, saddle nose, blindness

Front 36

Wha tis the histological hallmark of leprosy?

Back 36

1. Neurotropism

Front 37

Back 37

1. Tuberculoid leprosy--- granuloma following nerve course

Front 38

How do you tx paucibacillary leprosy?

Back 38

1. Rifampin

2. Dapsone

Front 39

How do you tx multibacillary leprosy?

Back 39

1. Dapsone, clofazamine, and rifampin

Front 40

What are the ssx of N. gonorrhoeae infection?

Back 40

1. Fitz-Hugh-Curtis

2. Ophthalmia neonatorum

3. Arthritis dermatosis--- tender pusutle on distal extremities

Front 41

How do you tx gonococcal infections?

Back 41

1. Ceftriaxone/cefepime

2. Azithro or doxy for chlamydia

Front 42

What is the vaccine for gonococcal infections?

Back 42

1. Polyvalent vaccine

Front 43

What is the MCC of granuloma inguinale?

Back 43

1. Klebsiella granulomatis

Front 44

What are the ssx of granuloma inguinale?

Back 44

1. Esthiomene: pseudo elephantiasis of genitals

Front 45

What are the MCC/ssx of chancroid?

Back 45

1. MCC: H. ducreyi

2. Unilateral painful adenitis: bubo

3. Phagedena--- spreading/sloughing ulceration, gangrenous balanitis

Front 46

What are the MCC/ssx of lymphogranulom venereum?

Back 46

1. C. trachomatis

2. Ssx: Herpetiform ulcer, bubos, fistulas

Front 47

How do you tx lymphgranuloma venereum?

Back 47

1. Doxycycline

Front 48

What are the ssx of vibrio vulnificus infection?

Back 48

1. Get from fish, shellfish, raw oyster

2. Hemorrhagic bullae, petechiae, purpura

3. MC on lower extremity

Front 49

How do you tx vibrio vulnificus infection?

Back 49

1. Tetracycline

Front 50

What is the MCC/ssx of malakoplakia?

Back 50

1. MCC: E. coli

2. Ssx: Non-sepcific cutaneous lesion

3. Usually in IC

Front 51

How do you tx malakoplakia?

Back 51

1. Quinolones

2. Bactrim

3. Clofazimine

Front 52

What is the MCC/ssx of rhinoscleroma?

Back 52

1. K. pneumoniae

2. Chronic granulomatous disease of nose-- rhinos, proliferative, fibrotic

3. Extensive mutilation

4. Hebra nose--- large nose

Front 53

What are the histiologic signs of rhinoscleroma?

Back 53

1. Mikulicz's cells--- parasitized histiocytes

2. Russell bodies--- eosinophilic bodies inside

Front 54

How do you tx rhinoscerloma?

Back 54

1. Fluoroquinolones

Front 55

What are the ssx of cat scratch disease?

Back 55

1. Epitrochlear/axillary LAD

Front 56

How do you tx cat scratch disease?

Back 56

1. Bactrim/erythromycin

Front 57

What are the MCC of bacillary angiomatosis?

Back 57

1. B. henslae

2. B. quintana

Front 58

Back 58

1. Bacillary angiomatosis

Front 59

What are the MCC of epidemic typhus? What is the vector?

Back 59

1. R. prowazekii

2. Vector= pediuclus humansu var corporis--- body louse

Front 60

What are the ssx of epidemic typhus?

Back 60

1. Gangrene of gainers, toes, ears

2. Fever, HA, myalgia, hypotension

Front 61

What are the ssx of murine typhus? MCC?

Back 61

1. MCC: R. typhi--- rat flea

2. Gangrene of gainers, toes, ears

3. Fever, HA, myalgia, hypotension

Front 62

What is the MCC of scrub typhus? Vector?

Back 62

1. R. tsutsugamushi--- chigger

Front 63

What are the ssx of scrub typhus?

Back 63

1. High fever, HA

2. Rash begins on day 5

3. deafness if untreated

Front 64

How do you tx scrub typhus?

Back 64

1. Tetracycline

Front 65

What are the vectors/MCC of RMSF?

Back 65

1. Wood tick--- D. andersoni

2. Dog tick--- D. variabilis

3. Lone star tick--- amblyomma americanum

Front 66

What are the ssx of RMSF?

Back 66

1. Petechial eruption on ankles, wrists, spread towards trunk

Front 67

What is the main complication of RMSF?

Back 67

1. Nephritis

Front 68

What is the MCC of rickettsialpox? Vector?

Back 68

1. R. akari

2. Vector: Rodent mite

Front 69

How do you dx/tx rickettsialpox?

Back 69

1. Dx: Weil-Felix negative

2. Tx: tetracyclines

Front 70

What is the MCC/vector of erlichiosis?

Back 70

1. E. chafeensis

2. Vector=ambylomma americanum--- lonestar tick

Front 71

What are the ssx of erlichiosis?

Back 71

1. Rash

2. Fever

3. Leukopenia/thrombocytopenia

Front 72

What is the characteristic histology of erlichiosis?1

Back 72

1. Mulberry-shaped intracyctoplasmic Microcolonies on giemsa

Front 73

What is the MCC of Lyme disease?

Back 73

1. B. burgdorferi

Front 74

What are the ssx of Lyme disease?

Back 74

1. Erythema migrans/flu

2. Bilateral Bells palsy, heart block

3. Arthropathy

Front 75

How do you tx Lyme disease?

Back 75

1. Doxycycine

2. Ceftriaxone

Front 76

What is the MCC/vector for the plague?

Back 76

1. Y. pestis

2. Xenopsylla cheopis