4Th Year - Pharmacology - Names Of Drugs

Front 1

Name 2 direct acting cholinomimetis which act on Muscarinic receptors, and 1 which acts on both muscarinic&nicotinic receptors

Back 1

Muscarinic direct agonists:
1. Bethanechol 2. Pilocarpine
Muscarinic&Nicotinic direct agonists:
1. Carbachol

Front 2

Name 1 indirect acting cholinomimetic with a short half-life, name 1 with very long half-life, name 1 which is a tetiary amine and crosses BBB

Back 2

1. Indirect cholinomimetic with short HL : Edrophonium(5-15min)
2. Indirect with very long HL: Parathion(7-30days)
3. Crosses BBB: Physostigmine (30min-2h HL)

Front 3

Name the prototype and 2 other non-selective muscarinic blockers. Name prototype of M1 selective blocker

Back 3

Non-selective: Atropine, Scopolamine, Ipratropium
M1 blocker: Pirenzepine

Front 4

Name 2 Nicotinic-Ganglionic blockers. Name 1 Nicotinic neuromascular blocker

Back 4

Ganglionic blocker: Hexamethonium, Trimethaphan
Neuromascular blocker- Tubocurarine

Front 5

Name a cholinesterase regenerator

Back 5

Pralidoxime

Front 6

Name 4 catecholamine sympathomimetics

Back 6

1. Norepi
2. Isoprotrenolol
3. Dopamine
4. Dobutamine

Front 7

Name 3 non-catecholamine symapthomimetics

Back 7

1. Ephedrine
2. Phenylephrine
3. Albuterol
4. Cocaine

Front 8

Name 2 indirect-releasers sympathomimetics.
Name 2 uptake inhibitors, indirect sympathomimetics

Back 8

Indirect releases sympathomimetics - Tyramine, Amphetamine
Indirect, uptake inhibitors sympathomimetics - Cocaine, tricyclic antidepressents

Front 9

Name an Alpha1 selective agonist. Name an Alpha 2 selective agonist. Name a Beta selective agonist with B1=B2 action

Back 9

Alpha1 - Phenylephrine
Alpha2 - Clonidine
B1=B2 - Isoprotrenolol

Front 10

Name a B1 selective agonist.
Name a B2 selective agonist. Name a Dopamine agonist.

Back 10

B1 - Dobutamine.
B2 - Terbutaline
Dopamine - Bromocriptine

Front 11

Name 3 B1 selective blockers
Name 3 non-selective B blockers

Back 11

B1 - Metoprolol, Atenolol, Esmolol
Non-selective B blocker - Propranolol, Labetolol, Timolol

Front 12

Name a non-selective Alpha blocker. Name a Alpha1 selective blocker. Name a Alpha2 selective blocker.

Back 12

Non-selective A blocker : Phentolamine, Phenoxybenzamine
Alpha1-selective blocker: Prazosin
Alpha-2 selective blocker: Yohimbine

Front 13

Name 2 Beta blockers with partial agonist activity.
Name a beta blocker with a very short half life. Name a beta blocker with a very long half-life

Back 13

Beta blockers with partial agonist activity : Acebutolol, Pindolol
Very short half life beta blocker- Esmolol (10min). Very long half life Beta blocker - Nadolol(14-24h)

Front 14

Name 4 types of drugs to treat hypertension

Back 14

Diuretics, Sympathoplegics, Vasodilators, AT antagonists

Front 15

Name 3 vasodilator drugs used to treat HT. Name 3 Angiotensin antagonists drugs used to treat HT

Back 15

Vasodilators for HT: Hydralizine, Minoxidil, Verapimil
Angiotensin antagonists:
Captopril (ACE In), Losartan(AT-II blocker)

Front 16

Name 3 classes of Anti-anginal drugs and give 2 examples to each one

Back 16

1.Vasodilators: Nitrates(Nitroglycerine)
2. Calcium channel blockers (verapamil, diltiazem, Nifedipine)
3. Beta blockers

Front 17

Give 5 classes of drugs used in heart failure and an example for each one

Back 17

1. Cardiac glycosides (Digoxin)
2. Positive inotropid digitalis substitutes (Dobutamine, amrinone)
3. Angiotensin antagoniists (captopril, losartan)
4. Diuretics(furosemide)
5. Vasodilators (nitroprusside, nitroglycerine)

Front 18

What are the classes of drugs used as Antiarrythmics

Back 18

I - sodium channel blockers
II - B blockers
III - Potassium blockers
IV - Ca blockers

Front 19

Give the 3 prototypes of the 3 classes of Class I antiarrhthmyics. Also give one more drug from the class.

Back 19

Class IA - Procainamide, Quinidine
Class IB - Lidocaine, Mexiletine
Class IC - Flecainide, Propafenone

Front 20

Give 2 prototypical and 2 non-prototypical Class III antiarrhythmics

Back 20

Prototypes -Sotalol, Ibutilide
Non prototypes - Dofetilide, Bretylium

Front 21

Give the 3 types of Calcium channel blockers. Which one is the prototype and approved as a Class IV antiarrhythmic drug

Back 21

Verapamil, Diltiazem, Nifedipine(a DHP). The only approved class IV anti-arrhythmic is Verapamil

Front 22

Give the prototypical carbonic anhydrase inhibitor + one more non prototype. Same for Loop diuretics.

Back 22

CA inhibitors - Acetazolamide is the prototype, Dorzolamide.
Loop diuretics - Furosemide, Ethacrynic acid

Front 23

Give the prototypical Thiazide diuretic + one more. Same for Potassium sparing diuretics

Back 23

Thiazides- Hydrochlorothiazide is prototype, Metolazone.
Potassium sparing - Spironolactone and Amiloride are prototypes, eplerenone is not.

Front 24

Two ADH agonists, Two ADH antagonists

Back 24

ADH agonists - ADH(duh), Desmopressin
ADH Antagonists - Demeclocycline, Lithium