This is the result of involuntary muscle contraction interfering with voluntary movements (Human Biology). Parkinson’s disease signs vary from person to person. Early symptoms may be insignificant and go unnoticed. Symptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides (Mayo Clinic). Rigidity or a resistance to movement affect most people with Parkinson’s disease, causes muscles to be tensed and contracted so that more individual feels stiff. The disease is also characterized by bradykinesia, which is the extreme slowness in movement. Simple tasks such as opening a door or reaching for a glass of milk can take several minutes. A person has difficulty performing routine work such as dressing, eating and walking. Another symptom of Parkinson’s disease is hypokinesia, a condition in which the range of motion is reduced (Human Biology). According to the laboratory manual, one of the diagnostic tools used to identify Parkinson’s is to study a patient’s handwriting to see whether the letters and words have progressively gotten smaller or even impossible to read. Some of the non-motor symptom include disturbances in cognition and sleeping habit, emotions such as mood, sensation and perception, olfactory system, autonomic function decrease and constant …show more content…
Parkinson 's Disease is caused by the death of dopamine-generating cells in a region in the midbrain called the substantia nigra. When dopamine levels decrease, it causes abnormal brain activity, leading to signs of Parkinson 's disease. The dopamine released by nerve cells of the substantia nigra stimulates another brain region, the corpus striatum. Without enough dopamine, the corpus striatum cannot control its targets, and so on down the line. Ultimately, the movement patterns of walking, writing, reaching for objects, and other basic actions cannot function properly, resulting in the symptoms of parkinsonism (Gulli, Laith