Status Epilepticus Case Studies

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Introduction

Status Epilipticus (SE) is a neurological emergency defined as a tonic, clonic or tonic clonic convulsive that last for at least 30 minutes [1, 2] which is the estimated duration necessary to cause injury to the central nervous system neurons [3] or can be defined as a condition with two or more separated seizures between which there is incomplete recovery of consciousness [3]. SE annual incidence of 10–40 per 100 000 population. The rate is higher among children < 1 year and adults > 65 years, and higher in men than women [4]. Status epilepticus is often linked to high mortality. About 20% of patients died within the first 30 days [5].

Status Epilepticus can be classified to: 1- Convulsive status epilepticus that is associated
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Febrile Status Epileptics can be defined as SE associated with fever in neurologically normal child. This type of SE is found to have a good prognosis [7]. The other type is Non-febrile Status epilepticus and the outcome depends on the etiology and the age of the child [8].The etiology can be divided to Idiopathic ( unknown cause), acute symptomatic (e.g. due to infections or metabolic disorders) and remote symptomatic ( e.g underlying or congenital neurologial disorder ) [7].

Status epilepticus is an emergency that required an immediate action to be taken. The goal of treatment is to stop the clinical and electrical seizure activity [9].

Komur, M., et al., retrospectively reviewed the medical record of 89 pediatric patients aged from 2 month to 18 years with convulsive status epilepticus in ICU in Turkey. They reported that seizure etiologies were remote symptomatic in most patient (52.7%), febrile (16.9%), acute symptomatic (13.5%) and unknown (16.9%) . Seizure control was achieved within 30 minutes in most patients (61.2%) . They also found that increasing the seizure duration increases the length of stay in the ICU and the mortality rate was low ( 3.4%) due to effective treatment [10].

treatment start with assessment and management of airway and circulation , and an antiepileptic drug to stabilize the patient and terminate the seizure activity[6,

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