I. Schizophrenia is a heritable disorder that is caused by nucleotide polymorphisms on over 100 different gene loci and counting. This neuropsychiatric disorder is thought to be influenced by microRNA abnormalities that provide psychological markers traceable through a patient’s genome to afford early detection (He 2017). Genomic studies uncovered that schizophrenia can be caused by various alleles in a genome that interact together. Signs and symptoms of the disease are linked through the Disconnection hypothesis that allows for molecular and neuronal pathophysiology. This pathophysiology allows for receptor functions and neurotransmitter systems to be studied and related to genomic …show more content…
Characteristic of schizophrenia are negative changes in behavior, cognition, mood, psyche, and speech
i. Behavior is often centered around isolation, aggression, and compulsiveness. Repetitive movements and lack of restraint or even self-harm are prominent as well, ii. Cognitive skills are lacking in that delusion and amnesia cloud the subject’s mind, causing irrational thoughts along with memory loss and confusion (Sullivan 2017), iii. Mood resembles a myriad of differing, extreme emotions from anger, to detachment, to sorrow, iv. Psychologically, those affected experience hallucinations, depression, paranoia, hearing voices and irrational amounts of fear,
v. People with schizophrenia are often unable to coherently vocalize their emotions and feelings and often have speech impediments.
B. Diagnosis of schizophrenia is difficult because symptoms can often be triggered by drug use such as LSD and those who are diagnosed properly often do not believe they have the disorder.
i. No single physical or lab test determines if one carries the disease, ii. Healthcare providers must analyze factors such as potential brain tumors, psychiatric health, or other possible medical