Antiemetics Research Paper

Improved Essays
Antiemetics

Overview:
Antiemetics are used for nausea and to prevent vomiting and also used for motion sickness. These drugs can be bought over the counter. (OTC)
Action:
Dimenhydrenate or Dramamine is an antihistamine. It should be taken one hour before travelling, and will prevent motion sickness. The antihistamine is available in children’s liquid formula and in a Less Drowsy Formula that may have fewer sedative side effects.
Meclizine hydrochloride (Bonine) treats vomiting and dizziness and do not operate machinery while taking this medication. This is available over the counter.

Anticholinergics

Hyoscine hydrobromide may be prescribed as a skin patch to relieve motion sickness and it is also available over the counter as tablets. Side effects may include dry mouth, drowsiness, difficulty passing urine, and dizziness. Antiemetic drugs work in various ways, for example, antihistamines and anticholinergics (also known as antimuscarinics) suppress the vomiting reflex; motility stimulants work by increasing movement through the gastrointestinal tract; and serotonin antagonists suppress signals to and from the vomiting centre in the brain. Emetrol is taken orally to relieve symptoms of nausea and vomiting due to overeating or viruses. Side Effects: Emetrol contains sugar and should not be used by diabetics. Pregnant or nursing women as well as children, should consult a doctor before using this. Doses of 800 to 1250 milligrams (mg) of Dimenhydrenate cause hallucinations. Some side effects of this medication include; constipation, blurred vision, dry mouth and restlessness. Contraindications of Dimenhydrenate Do not give this medication to a child younger than 2 years old. Misuse of antihistamines in young children can result in death. Do not use this medication if you are allergic to it. Conditions Treated: Dimenhydrenate treats motion Sickness. Motion sickness occurs when the brain receives conflicting signals from the motion-sensing part of the body, the eyes, the inner ears and the nerves in your extremities. For instance, if you watch a movie with really rapid motion, your eyes sense the motion but your inner ear and joints do not. When the brain receives these conflicting signals it activates a response that can make you sick. Dimenhydrenate can also be used to treat Meniere’s disease. This a disease in which you experience vertigo, tinnitus, hearing loss and a feeling of fullness in the ear. Symptoms are believed to have occurred because of buildup of fluid in the inner ear. There is no cure and about 10 % of cases run in families. Attacks are treated with medication like Dimenhydrenate. References: http://www.medicinenet.com/antiemetics/page2.htm http://www.everydayhealth.com/drugs/dramamine Analgesics Overview Analgesics belong to a class of drugs used to treat pain. There are two broad categories of analgesics which are narcotic and non- narcotic and NSAID (non-steroid anti- inflammatory drugs) are in this category, as well as aspirin, called acetylsalicylic acid (ASA) derived from salicylic acid and ibuprofen. This is the most common mild analgesic used. Anti-inflammatory drugs alleviate pain and reduce inflammatory responses. They are used for short-term pain relief, such as arthritis or a headache. Most anti-inflammatory analgesics are derived from salicylic acid, pyrazolone and phenacetin. These drugs do not block the conduction of nerve impulses or affect consciousness. That is the difference between and Analgesic and an anesthetic. When aspirin is taken orally, it is well absorbed from the gastrointestinal tract (GIT) and
…show more content…
It takes 15-20 to take effect and lasts for 4-8 hours. Salicylates cross the blood brain barrier. It is metabolized in the liver and excreted in the urine.
Side Effects
Hypersensitivity to aspirin type drugs are to an accumulation of prostaglandins, after pathways break down prostaglandins are blocked. Inhibition of prostaglandin synthesis may result in some serious side effects like peptic ulcers, and problems with blood clotting. Liver damage sometimes occurs with aspirin and renal or kidney toxicity with NSAIDs. Aspirin is also the cause of Rye Syndrome, a degenerative disease of the brain and fatty tissue of the liver.
Contraindications of acetylsalicylic acid aspirin (ASA)
People who are allergic to aspirin or NSAIDS should not take it. Taking low dose 81mg daily aspirin should not be taken by healthy people to prevent a first heart event or stroke. There is an increased risk of bleeding in the stomach, intestines and in the brain. So do not take it if you have a serious allergy or a history of

Related Documents

  • Improved Essays

    Part B Q1. The normal dose of paracetamol is very safe to use and it is not over 4g per 24 hours; however, when the patient take more than 6g per 24 hours of paracetamol, the liver necrosis will happen within 10 to 12 hours and liver damage may occur within 24 to 48 hours. For the metabolism, most of the paracetamol is converted to nontoxic metabolites by the phase II conjugation of glucuronide and sulfate and a small amount of paracetamol is oxidized by the Cytochrome P450 (CYP) enzymes in the phase I metabolism. In this phase, CYP1A2 and CYP2E1 enzymes convert paracetamol to N-acetyl-p-benzoquinoneimine (NAPBQI) which is highly toxic substances.…

    • 885 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Major adverse effects: Gastrointestinal bleeding, dyspepsia, epigastric distress and nausea. Nursing implications: Monitor for the onset of tinnitus, hyperventilation, headache, tinnitus, , agitation, mental confusion, stupor, diarrhea, and sweat. If these symptoms appear, withhold medication and inform physician or other health care professional right away (Vallerand & Sanoski, 2013). Patient teaching: tell patient that aspirin is given prophylactically and they should take only prescribed dose.…

    • 1272 Words
    • 6 Pages
    Improved Essays
  • Decent Essays

    Take this drug by mouth once a day. Take it with or without food and a full glass of plain water. Side Effects This drug can cause cough, wooziness, sleepiness, headache loose stool,…

    • 346 Words
    • 2 Pages
    Decent Essays
  • Great Essays

    Altered Pharmacodynamics

    • 837 Words
    • 4 Pages

    Pharmacodynamics: Ibuprofen is a NSAID with anti-inflammatory; analgesic and antipyretics effects are the results of the ability to block the cyclooxygenase (COX) enzyme system, leading to the inhibition of the synthesis of prostaglandins [6]. COX is the enzyme used for prostaglandin biosynthesis [3]. Both COX-1 and COX-2 enzymes are involved with prostaglandin production. The inhibition of these enzymes results in decreased synthesis of prostaglandin thus decreasing pain, fever, and swelling [4].…

    • 837 Words
    • 4 Pages
    Great Essays
  • Decent Essays

    Spironolactone Case Study

    • 538 Words
    • 3 Pages

    reduction in the hypertension. Canrenone is the active metabolite which is thought to play a significant part in exerting the pharmacological effects of the drug Spironolactone. There are numerous side effects of Spironolactone, and some people even found that it had the potential to cause certain types of cancers as well, hence as a result questioning its safety. There are also other adverse effects of Spironolactone which involve the issue of severe hyperkalaemia, especially when Spironolactone is co-administered with other diuretics, non-steroidal anti-inflammatory drugs (NSAIDs) and other angiotensin-converting enzyme (ACE) inhibitors.…

    • 538 Words
    • 3 Pages
    Decent Essays
  • Improved Essays

    In David Badcott’s position paper “Big Pharma: A Former Insider’s View,” Badcott makes the assumption that the future of healthcare will predominately focus on the administration pharmaceutical drugs, which is not true because drugs can cause complications in individuals and thus require medical attention from healthcare practitioners. Badcott implies that the services of healthcare professionals will become obsolete. This implication is not true because there are healthcare services that do not primarily focus on treatment with medicinal drugs. Although pharmaceutical drugs play a huge role in the current healthcare industry, the role of the medical practitioner is as equally important. Badcott states the effectiveness of newer pharmaceutical drugs allow for the reduction of “total health expenditures by lowering the need for other types of medical services” (Badcott 252).…

    • 706 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Naproxen Research Paper

    • 437 Words
    • 2 Pages

    to cause GI (gastrointestinal) bleeding when mixed with naproxen. This is also a probability if naproxen is mixed with drugs. Naproxen sodium may also increase the toxicity of lithium. This could increase the risk for lithium side effects. When taken with methotrexate naproxen sodium can increase the levels of methotrexate also increasing the risk for methotrexate side effects.…

    • 437 Words
    • 2 Pages
    Decent Essays
  • Improved Essays

    Acetaminophen Essay

    • 563 Words
    • 3 Pages

    Acetaminophen is one of the most widely used analgesics and anti-pyretics around the world1. Because of its safety, acetaminophen is the most common drug used in children for the relief of fever and pain2, 3. It is available in both oral (tablet & liquid) and rectal forms (suppositories). Various research studies have indicated that both forms have potential efficacy for the treatment of fever in children; however, there may be variations in administration, absorption and toxicity4-6. The oral form is the more common and acceptable form of administration among physicians.…

    • 563 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Symptoms of allergy can be treated with H1 antihistamines. The purpose of treatment is to prevent histamine to stimulate the receptors, why they consist of the same core structure as histamine . These H1 antihistamines constitute the second most commonly used class of medications after antibiotics and there are many varieties used in different conditions . H1 antihistamines are classified into six groups: ethanolamines, ethylene diamines, alkylamines, piperazines, piperadines, and phenothiazines . Since this classification is of limited clinical relevance, H1 antihistamines are also being classified as first- and second generation.…

    • 543 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Nurses that administer medication are accountable for recognizing the medications prescribed, the patients need for the medication and their therapeutic and non-therapeutic effects (Crisp and Taylor, 2013). The purpose of this essay is to examine the importance of understanding the registered nurse’s role and responsibilities when administering medication. Equally, it will cover all the key concepts of legal and ethical issues relevant to medication administration. The legal and ethical issues are discussed in relation to the documents NZ Nurses Organisation Guidelines for Nurses on the Administration of Medicines (2014), Nursing Council of NZ Competencies for Registered Nurses (2016), Health Practitioners Competence Assurance Act 2003, Local…

    • 1927 Words
    • 8 Pages
    Great Essays
  • Improved Essays

    Vertigo Research Paper

    • 393 Words
    • 2 Pages

    Central nervous system disease that cause vertigo include disease of the brainstem. vascular nervous system causes malformations, tumor of the brainstem and cerebellum ,multiple sclerosis, , vertebrobasilar migraine. Vertigo of central origin often becomes disabling. The associated nystagmus is often non fatigable, the orientation of this type of vertigo is vertical rather than horizontal, without latency, and unsuppressed by visual fixation.…

    • 393 Words
    • 2 Pages
    Improved Essays
  • Great Essays

    Acute Gout Case Studies

    • 1659 Words
    • 7 Pages

    Gout is a “disorder of metabolism that allows uric acid or urate to accumulated in the blood and tissues”(Rothschild, 2015, p. 3). It is more common in men than in women and has a higher incidence in 70 to 79 years of age. The gout syndrome is “ caused by alteration in purine metabolism, the end product which is uric acid. This results in hyperurecemia and in the deposition of urate crystals in various tissues (Woo & Wynne, 2011, p. 869). Hyperuricemia can occur due three mechanisms: 1.…

    • 1659 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    When the salicylic acid was weighed in the beginning, weighing paper was supposed to be used to weigh the salicylic acid on balance, but instead a lab paper was used instead. This could have given an inaccurate mass reading due to the movement of bent layer of papers on the scale, causing the mass fluctuate. This could have led to imperfections in the purity of our aspirin, because of incorrect amounts of salicylic acid measured. Also, 40 ml of water was added to decompose the acetic anhydride right after the salicylic acid completely dissolved. Doing this before adding an initial 4 ml of water could have impact the decomposition process.…

    • 993 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Willows Research Paper

    • 1586 Words
    • 7 Pages

    The genus Salix, or Willow, consists of around 400 species of trees and shrubs which can be found in nearly every continent, save for Australia and Antarctica. The wood of willows is light and therefore easily molded, and the plants versatility has lead to it developing a variety of applications ranging from basket-weaving to fire-starting. The near ubiquity and widespread applicability of willows has lead to the plant developing symbolic meaning as well, with the plant featuring prominently in the Bible and various English superstitions. Willows have been featured in a number of works of fiction as well, with their legacy eventually culminating in pivotal roles in Shakespeare 's Hamlet and JK Rowling’s Harry Potter series.…

    • 1586 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    Celecoxib Research Paper

    • 935 Words
    • 4 Pages

    1. INTRODUCTION 1.1 GENERAL CHARACTERISTICS OF CELECOXIB Celecoxib is a non-steroidal anti-inflammatory drug, which was the first COX-2 inhibitor approved by the FDA. It is mainly used for the treatment of osteoarthritis, rheumatoid arthritis, and familial adenomatous polyposis. Celecoxib was primarily designed to decrease the risk of adverse gastrointestinal effects, but several reports of cardiovascular events expressed concerns about its use.…

    • 935 Words
    • 4 Pages
    Improved Essays