There are two phases of asthmatic symptoms, the acute phase response and the late phase response. The acute phase response occurs within a few minutes, and it involves an interaction of allergen and microphages. Which means it involves the immune system and up-regulation of T cells. And T- cells causes the production of interleukins which causes sever bronchospasm. The late phase response occurs in 2 to 6 hours and lasts approximately 12 to 24 hours (Peterson & Arcangelo, 2013). Interleukins furthermore cause the proliferation eosinophils which plays a significant role in chronic airway inflammation.
