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9 Cards in this Set
- Front
- Back
What is the trade name for Alefacept?
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Amevive
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What is the trade name for Efalizumab?
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Raptiva
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What are the 2 main "biologic" agents, not TNF-alpha inhibitors?
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Alefacept and Efalizumab
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This biologic is a recombinant dimeric fusion protein, made from the portion of LFA-3 that binds to CD2 and the Fc portion of IgG
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Alefacept (Amevive)
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This biologic is recombinant humanized IgG monoclonal antibody that binds to the human subunit CD11a in LFA-1
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Efalizumab (Rapitva)
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Efalizumab (Raptiva) binds to what subunit in LFA-1?
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CD11a subunit
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Both biologics, Alefacept (Amevive) and Efalizumab (Raptiva) are manufactured inside of what animal part?
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Chinese hamster ovary
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Which biologic is a recombinant dimeric fusion protein made up of LFA-3 and Fc IgG?
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Alefacept (Amevive)
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Which biologic is a recombinant humanized IgG that binds to LFA-1?
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Efalixumab (Raptiva)
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