Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
28 Cards in this Set
- Front
- Back
Sulfonamides
|
Kernicterus
|
|
Aminoglycosides
|
Ototoxicity
|
|
Fluoroquinolones
|
Cartilage damage
|
|
Erythromycin
|
Acute cholestatic hepatitis (in mother)
|
|
Clarithromycin
|
Embryotoxic
|
|
Tetracyclines
|
Discolored teeth, inhibited bone growth
|
|
Ribavirin
|
Teratogenic
|
|
Griseofulvin
|
Teratogenic
|
|
Chloramphenicol
|
Gray baby
|
|
Alcohol
|
Microcephaly, ASD, mental retardation
|
|
Cocaine
|
Microcephaly, renal agenesis, congenital heart disease
|
|
Diethylstilbestrol
|
Vaginal or cervical clear cell carcinoma, mullerian defects
|
|
Phenytoin
|
Nail and distal phalynx hypoplasia, cleft lip and/or palate
|
|
Retinoic acid (distinct from vitamin A)
|
Craniofacial defect, CNS defect, cardiovascular defect
(disrupts function of HOX gene) |
|
Thalidomide
|
Amelia (absent limbs), phocomelia (seal-like limbs)
|
|
Tobacco
|
IUGR, low birth weight
|
|
Valproate
|
Neural tube defects
|
|
Warfarin
|
Nasal hypoplasia, agenesis of corpus callosum
|
|
Leading cause of birth defects
|
Alcohol
|
|
Renal damage
|
ACE inhibitors, AII receptor blockers
|
|
Placental abruption
|
Cocaine
|
|
Cleft palate, cardiac abnormalities, spontaneous abortion
|
Vitamin A excess
|
|
Flipper limbs
|
Thalidomide
|
|
Bone deformities, fetal hemorrhage, abortion
|
Warfarin
|
|
Absence of digits
|
Alkylating agents
|
|
CN VIII toxicity
|
Aminoglycosides
|
|
Neural tube defects
|
Folate antagonists
|
|
Limb dislocation, heart and lung fistulas; mechanism may include inhibition of cell migration
|
Alcohol
|