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59 Cards in this Set

  • Front
  • Back
A(n) ________ acid is an acid that can leave solution and enter the atmosphere.
volatile

In a lean adult male, the body consists of about ________ percent water.

60

The maintenance of normal volume and composition of extracellular and intracellular fluids is vital to life. List and briefly describe the kinds of homeostasis involved.

Three types of homeostasis are involved: fluid balance, electrolyte balance, and acid-base balance. Fluid balance means that the total quantity of body water remains almost constant and that the distribution between the ICF and ECF are normal. Electrolyte balance implies the same thing for ions. Acid-base balance means that the pH of the ECF is maintained in the range of 7.35 to 7.45, and that gains or losses of hydrogen ion as a consequence of metabolism are followed by equivalent losses or gains so as to maintain constant buffer reserves.

Secretion of potassium into the urine isincreased by aldosterone.associated with the reabsorption of sodium from the distal tubules and collecting ducts.minimal because the human diet includes very little potassium.A, B, and CA and B only

A and B only

Which hormone(s) is released by heart muscle in response to excessive chamber volume?


ADH


PTH


acetylcholine


aldosterone


natriuretic peptides

natriuretic peptides

Which hormone most affects the osmolarity of blood?


angiotensin


IIepinephrine


ANP


PTH


ADH

ADH

________ promotes water reabsorption at the kidneys and stimulates thirst.

ADH

Which hormone stimulates the thirst mechanism?


epinephrine


ADH


ANP


BNP


aldosterone

ADH

The ions in highest concentration in the intracellular fluid?


aresodium, potassium, and bicarbonate.


potassium, chloride, and bicarbonate.


sodium, potassium, and calcium.


proteins, potassium, and phosphate.


potassium, hydrogen, and chloride.

proteins, potassium, and phosphate.

Angiotensin II produces a coordinated elevation in the ECF volume by


causing the release of ADH.


stimulating thirst.


triggering the production and secretion of aldosterone.


both A and B


A, B, and C

A, B, and C

A(n) ________ consists of a combination of a weak acid and its associated anion.

buffer

The most common problems with electrolyte balance are caused by an imbalance between gains and losses of


potassium ions.


sodium ions.


electrons.


calcium ions.


chlorine ions.

sodium ions

A patient on a ventilator subjected to excessive minute volume is at risk for


respiratory alkalosis.


metabolic alkalosis.


respiratory acidosis.


metabolic acidosis.

respiratory alkalosis.

The ions in highest concentration in the extracellular fluid are


sodium, hydrogen, and chloride.


sodium, potassium, and phosphate.


sodium, potassium, and bicarbonate.


sodium, chloride, and bicarbonate.


sodium, potassium, and calcium.

sodium, chloride, and bicarbonate.

All of the following are components of ECF, except


peritoneal fluid.


RBCs.


cerebrospinal fluid.


aqueous humor.


lymph.

RBCs

A(n) ________ acid is an acid that cannot leave solution and enter the atmosphere.

fixed or nonvolatile

A patient who has been both vomiting and having diarrhea is losing ________ from his body.


hydrogen ion


sodium


water


bicarbonate ion


all of the above

all of the above

Which of the following descriptions best fits the acid-base disorder respiratory acidosis?


consequence of prolonged vomiting


consequence of tissue hypoxia, for example in ischemic conditions


consequence of hyperventilation, for example in fever or mental illness


consequence of reduced alveolar ventilation, for example due to emphysema

consequence of reduced alveolar ventilation, for example due to emphysema

When the pH falls below 7.35, a state of ________ exists.

acidosis

When the pH rises above 7.45, a state of ________ exists.

alkalosis

Approximately ________ liters of peritoneal fluid are produced and reabsorbed each day.


7


9


15


10


20

7

Hypercapnia refers to elevated levels of ________.

carbon dioxide

Excess hydrogen ion is eliminated from the body largely by


the feces.


buffers.


the kidneys.


sweating.


the liver.

the kidneys

Severe kidney damage (such as glomerulonephritis) often leads to


metabolic alkalosis.


metabolic acidosis.


respiratory alkalosis.


respiratory acidosis.

metabolic acidosis.

To reduce brain swelling by pulling water out of brain cells, a substance can be injected intravenously to increase the osmotic pressure of interstitial fluid. Which of the following properties can this substance not have in order to be effective?


impermeable to brain plasma membranes


permeable to brain plasma membranes


permeable to capillary endothelium


nontoxic to neurons soluble in water

permeable to brain plasma membranes

Will hyperventilation raise or lower pH?

raise

Exchange between the two main subdivisions of ECF occurs primarily at the


tissues.


muscles.


arteries.


capillaries.


veins.

capillaries.

When pure water is consumed,


osmolarities of the two fluid compartments fall.


the ECF becomes hypertonic to the ICF.


the volume of the ICF decreases.


a fluid shift occurs and the volume of the ICF decreases.


the volume of the ECF decreases.

osmolarities of the two fluid compartments fall.

The extracellular fluid (ECF) consists of the


cerebrospinal fluid.


plasma and lymph.


interstitial fluid.


all of the above


A and B only

all of the above

When water is lost, but electrolytes are retained,


both the ECF and the ICF become more dilute.


the osmolarity of the ECF falls.


osmosis moves water from the ICF to the ECF.


there is an increase in the volume of the ICF.


both B and D

osmosis moves water from the ICF to the ECF.

The principal ions in extracellular fluid are ________, ________, and ________.

sodium, chloride and bicarbonate

Prolonged vomiting can result in


respiratory alkalosis.


metabolic acidosis.


respiratory acidosis.


metabolic alkalosis.

metabolic alkalosis

When the pH of the extracellular fluid drops, the


kidneys excrete more hydrogen ions.


kidneys excrete more bicarbonate ions.


kidneys excrete fewer bicarbonate ions.


A and B only


A and C only

A and C only

A person with poorly controlled diabetes mellitus will develop


metabolic alkalosis.


respiratory acidosis.


respiratory alkalosis.


metabolic acidosis.

metabolic acidosis.

Which of the following will stimulate thirst?drying the mucosa of the mouth and pharynx


an increase in the osmotic pressure of interstitial fluid within the hypothalamus


angiotensin II acting on the hypothalamus


A and B only


A, B, and C

A, B, and C

About two-thirds of the body fluid is within cells and is termed ________ fluid.


interstitial


extracellular


intercellular


intracellular


vital

intracellular

Which of the following descriptions best fits the acid-base disorder metabolic alkalosis?


consequence of tissue hypoxia, for example in ischemic conditions


consequence of reduced alveolar ventilation, for example due to COPD


consequence of prolonged vomiting


consequence of hyperventilation, for example in fever or mental illness

consequence of prolonged vomiting

Aldosterone


is secreted in response to elevated levels of potassium in the blood.


promotes sodium retention in the kidneys.


helps decrease blood volume and lower blood pressure.


A, B, and C


A and B only

A and B only

The primary role of the carbonic-acid-bicarbonate buffer system is to


buffer carbonic acid formed by carbon dioxide.


increase ventilation.


limit pH changes caused by organic and fixed acids.


buffer the urine.


buffer stomach acid.

limit pH changes caused by organic and fixed acids.

In response to respiratory alkalosis, the


respiratory rate increases.


kidneys secrete more hydrogen ions.


tidal volume increases.


kidneys retain more hydrogen ions.


kidneys conserve bicarbonate.

kidneys retain more hydrogen ions.

A person who consumes large amounts of sodium bicarbonate ("baking soda") to settle an upset stomach risks


respiratory alkalosis.


respiratory acidosis.


metabolic acidosis.


metabolic alkalosis.

metabolic alkalosis.

Substances that can carry electrical current across cell membranes are called


buffers.


electrons.


electrolytes.


osmoregulators.


nonelectrolytes.

electrolytes

In an adult female, the body consists of about ________ percent water.


70


40


60


50


80

50

Calcium reabsorption by the kidneys is promoted by the hormone


ADH.


calcitonin.


parathyroid hormone.


aldosterone.


cortisol.

parathyroid hormone.

A chemical that minimizes changes in the pH of a body fluid by releasing or binding hydrogen ion is called a(n)


buffer.


compensation.


acid.


alkali.


electrolyte.

buffer

The principal cation in intracellular fluid is


magnesium.


potassium.


calcium.


chloride.


sodium.

potassium.

The amount of potassium excreted by the kidneys is regulated mainly by


glucocorticoids.


aldosterone.


ADH.


atrial natriuretic peptides.


parathormone.

aldosterone.

Which hormone plays a central role in determining the rate of sodium reabsorption and potassium secretion?


BNP


aldosterone


ANP


ADH


epinephrine

aldosterone

The normal pH range for ECF is ________ to ________.

7.35 to 7.45

Consuming a meal high in salt will


cause hypotension.


result in a temporary increase in blood volume.


drastically increase the osmolarity of the blood.


decrease thirst.


activate the renin-angiotensin mechanism.

result in a temporary increase in blood volume

Homeostatic mechanisms that monitor and adjust the composition of body fluids respond to changes in the ________ fluid.

extracellular

Antidiuretic hormoneis secreted by the adenohypophysis.


stimulates water intake.


stimulates water conservation by the kidneys


A, B, and C


B and C only

B and C only

The release of atrial naturetic peptides from the heart will cause the body to


conserve sodium ions.


decrease ECF.


excrete sodium ions.


both A and B


both B and C

both B and C

Intracellular fluid (ICF) is found only within


the cells of the body.


blood vessels.


the cerebrospinal fluid.


the interstitial space.


lymph.

the cells of the body

A person with emphysema will exhibit signs of


acute respiratory acidosis.


chronic respiratory alkalosis.


chronic metabolic acidosis.


chronic respiratory acidosis.

chronic respiratory acidosis.

Fred has chronic emphysema. Blood tests show that his pH is low but almost normal but his bicarbonate levels are elevated significantly. How can this be? What would urinalysis show?

Emphysema limits alveolar ventilation, leading to increased carbon dioxide in Fred's body. Since Fred's condition is chronic (long term) his body has compensated for the excess carbonic acid (the result ofhypercapnia due to poor ventilation) by increasing the amount of bicarbonate to match the elevated level of hydrogen ion. This compensation for respiratory acidosis was accomplished by the kidney's secretion of hydrogen ion both in the PCT and DCT and the retention of bicarbonate from the elevated carbonic acid. Urinalysis would indicate a very low pH and high levels of ammonia, produced by the distal tubule to absorb the secreted hydrogen ion.

Why does potassium concentration rise in patients with acidosis? What is this called? What effects does it have?

When pH is low, hydrogen ion levels in the blood are high and also in the interstitial and peritubular fluid. Hydrogen ion competes with potassium ion for the sodium countercurrent exchanger in the tubules. As hydrogen ion secretion rises (which compensates for the acidosis), potassium is retained and hyperkalemia develops. If severe enough, muscle cramps and cardiac arrhythmias result.

Which of the following descriptions best fits the acid-base disorder respiratory alkalosis?


consequence of tissue hypoxia, for example in ischemic conditions


consequence of reduced alveolar ventilation, for example due to COPD


consequence of prolonged vomiting


consequence of hyperventilation, for example in fever or mental illness

consequence of hyperventilation, for example in fever or mental illness

Hypoventilation leads to

respiratory acidosis.


respiratory alkalosis.


metabolic alkalosis.


metabolic acidosis.

respiratory acidosis.