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47 Cards in this Set
- Front
- Back
what are the low potency antipsychotics
|
chlorpromazine
thioridazine |
|
what are the side effects of thioridazine
|
most cardiotoxic in OD
irreversible retinal pigmentation |
|
what are the side effects of chlorpromazine
|
hepatic toxicity
derm problems (skin eruptions, discoloration) deposits in lens and cornea most sedating |
|
are low or high potency antipsychotics more associated with neurologic side effects?
non-neurologic? |
high potency
low potency |
|
examples of high potency antipsychotics
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haloperidol
perphenazine fluphenazine |
|
what are EPS
|
pseudoparkinsonism
akathisia acute dystonia |
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aside from EPS what are other neurologic side effects
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TD
NMS decreased seizure threshold |
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how to treat acute dystonia
|
anticholinergic
antihistamine |
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how to treat NMS
|
stop the offending drug immediately
give skeletal muscle relaxant provide medical support switch to low potency med |
|
how to treat TD
|
substitute low potency or atypical antipsychotic
|
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how to treat pseudoparkinsonism
|
anticholinergic (genztropine, ex)
b/c DA normally suppresses ACh activity, if you give anticholinergic it will cause increased release of DA and relieve sx can also tx with antihistamine |
|
which neuro side effect takes >6mo to develop?
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TD
|
|
Side effects of amitryptiline
|
sedation
anticholinergic |
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which HCA is most serotonin specific
|
clomipramine
|
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which HCA is least sedating
|
desipramine
|
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which HCA has the least anticholinergic effects
|
desipramine
|
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which HCA stimulates appetite
|
desipramine
|
|
what are the effects of desipramine
|
least sedating
stim appetite least anticholinergic |
|
effets of doxepin
|
sedation
antihistaminergic anticholinergic |
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which HCA is likely to cause orthostatic hypotension
|
imipramine
|
|
which HCA may cause seizures
|
maprotiline
|
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which HCA has low cardiotoxicity
|
maprotiline
|
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which HCA is LEAST likely to cause orthostatic hypotension
|
nortriptyline
|
|
other than depression, uses for amitryptiline
|
depresssion with insomnia
chronic pain |
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other than depression, uses for clomipramine
|
OCD
|
|
other than depression, uses for desipramine
|
panic do
depression in elderly eating DO (think of side effects) |
|
other than depression, uses for doxepine
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GAD
PUD |
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other than depression, uses for maprtoiltine
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anxiety with depressive features
|
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other than depression, uses for nortriptyline
|
depression in elderly
pruritus pts with cardiac dz |
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which HCAs are good for treating depression in elderly?
|
nortriptyline
desipramine |
|
General side effects from SSRIs?
|
SIG HAS
Sexual side effects Insomnia GI probs HA Anorexia Serotonin syndrome (if given w MAOIs) |
|
What are SSRIs used to treat?
|
OCD (fluvoxamine)
Premature ejac Panic d/o PMDD (fluoxetine) Social phobia (paroxetine) Hypochondriasis Chronic pain PTSD paraphilias |
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which SSRI --> weight loss
|
fluoxetine
|
|
which SSRI --> agitation and insomnia
|
fluoxetine
"one FLU over the cuckoo's nest" |
|
which SSRI is most sedating
|
paroxitine
|
|
which SSRI is most anti-cholinergic
|
paroxitine
|
|
which of sSRIs is most likely --> GI probs
|
sertraline
|
|
which SSRI is most cardiotoxic
|
citalopram
|
|
SNRI
|
Venlafaxine
duloxetine 5HT and NorE reuptake inhib |
|
NDRI
|
buproprion
norE/DA reuptake inhib |
|
SARI
|
Nefazodone
Trazodone 5HT antagonist and reuptake inhib |
|
NASA
|
Mirtazapine
norE and 5HT antag |
|
advantage to SNRIs
|
rapid sx relief
few sexual side effects |
|
other than depression, uses of duloxetine
|
refractory depression
urine stress incontinence |
|
other than depression, uses of venlafaxine
|
refractory depression
GAD social phobia |
|
contradindications for buproprion
|
seizures
eating d/o psychosis (at higher doses, high DA effects) mania |
|
other than depression, uses of MAOIs
|
atypical depression
pain d/o eating d/o panic d/o social phobia |