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68 Cards in this Set
- Front
- Back
The treatment of choice in the lung carcinoma is the following?
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1. Ethioposidine
2. Cisplatin |
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The strong, centrally acting antitussive agent which may easily produce drug dependency is
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Pholcodine
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The main side effect of Fluticasone therapy is the following
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Cushing's syndrome
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Hydrochlorothiazide produces
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hypokalemic metabolic alkalosis
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Which agent should be used to treat acute hypercalcemia
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Furosemide
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Demeclocycline
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1. is a tetracycline antibiotic
2. neutralizes ADH influence on the kidney 3. can be hepatotoxic |
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The net effects of PTH activity are the following
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1. increased serum calcium
2. depressed serum phosphorous 3. increased calcitriol production |
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Calcitonin is not used in
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hypocalcemia
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Which of the following statements about the estrogens is FALSE
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they potentiate parathromon action on the bones
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Which agent is not used for the treatment of hypercalcemia?
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Triamteren (only secondary effect of co-administrated drug)
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Alcohol intake evokes the following
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inhibition of platelet aggregation
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Ethylene glycol poisoning is not treated with
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methanol
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Medication with penicillamine should be terminated in patients who present with the symptoms of
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autoimmune disorders
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An immunosuppressive drug without capability of suppressing immune response once it's already fully developed is
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cyclosporine
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Drugs which may cause renal injury due to impaired blood flow in some patients are the following
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NSAIDs
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Multidrug resistance of neoplastic cells against many unrelated compounds may be inhibited by the use of
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addition of verapamil to the mixture of drugs
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Currently approved treatment of septic shock includes all of the following EXCEPT
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NOS inhibitors
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Adverse effects of antihistaminic decongestants include
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urinary retention
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20% low sodium albumin should not be used in patients suffering from
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Addison's disease
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Drugs causing respiratory depression due to blockade of neuromuscular junction are all of the following except
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opioids
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Which of the following symptoms is NOT likely to result from iron intoxication?
a. vomiting b. necrotizing gastroenteritis c. blurred vision d. abdominal pain |
c. blurred vision
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Propranolol may be beneficial in thyrotoxicosis because
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it reduces tachycardia
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Which of the following drugs is used in the treatment of thyroid storm?
a. potassium iodide b. propylthiouracil c. propranolol d. all of the above |
d. all of the above
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Which of the insulin preparations can be given i.v.?
a. regular insulin b. insulin lente c. insulin ultralente d. insulin NPH |
a. regular insulin
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Alternate dat administration is used in the case of
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mitotane
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Which of the following conditions are the contraindication for the use of glucotricosteroids
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peptic ulcer
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Which of the following should be treated with glucocorticosteroids?
a. allergic conjunctivitis b. acute uveitis c. inflammatory bowel disease d. all of the above |
d. all of the above
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Phenformin is no longer used in the USA because
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it causes lactic acidosis
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Oral antidiabetic drug with the longest duration of action is
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chlorpropamide
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A substance that enhances probability of ovulation by blocking the inhibitory effect of estrogens and this stimulating the release of gonadotropin from the pituitary
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clomiphene (Clomid)
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Metyrapone is useful in testing the endocrine functioning of the
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pituitary-adrenal axis
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Aplastic anemia is sometimes encountered after treatment with any of the following drugs EXCEPT
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propranolol
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Drug induced granulocytopoenia is not dose dependent if the mechanism involved is the following:
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bone marrow hypoplasia
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Hemolytic anemia may be typically precipitated in G6P dehydrogenase deficient patients by
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primachine
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Cholestasis could be the side effect of all of the below EXCEPT:
a. Acetaminophen b. Morphine c. Cycloserine d. Anabolic steroids |
c. Cycloserine
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The osmotic laxative capable of inducing prompt (within few hours) bowel movement is
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Magnesium citrate
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The drug used for the treatment of secretory diarrhea due to its hormone release inhibiting properties is
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Octreotide
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Parenterally administered proemetic drug is
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Apomorphine
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All of the following drugs protect the GI tract from ulceration EXCEPT:
a. Cimetidine b. NSAIDs c. Omeprazole d. Calcium carbonate |
b. NSAIDs
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Use of magnesium-containing antacids is most likely to cause
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Diarrhea
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Use of aluminum-containing antacids is most likely to cause
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constipation
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Misoprostol is a derivative of
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PGE-1
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Standard H2-blocker therapy for mild-duodenal ulcers last
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4-8 weeks
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Oxytocin
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is used to treat postpartum hemorrhage
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Drugs that bind to the receptor in the cell membrane and increase cAMP concentration include all of the following EXCEPT:
a. ACTH b. isoproterenol c. hydrocortisone d. glucagon |
c. hydrocortisone
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Drugs that promote the release of insulin include all of the following EXCEPT
a. chlorpropamide b. glyburide c. glipizide d. tolamide |
d. tolamide
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Drugs that operate via cytoplasmic receptors include the following EXCEPT:
a. levothyroxine b. dexamethasone c. estriol d. mitotane |
a. levothyroxine
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Which of the following steroids has the LEAST mineralocorticoid potency?
a. fludrocortisone b. hydrocortisone c. cortisone d. beclomethasone |
d. beclomethasone
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Bromocriptine is used to treat some cases of amenorrhea because
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it inhibits prolactin release
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Adverse reactions associated with prednisone include all of the following EXCEPT
a. psychoses b. peptic ulcers c. increased susceptibility to infection d. depression |
d. depression
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Use of aluminum-containing antacids is most likely to cause
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constipation
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Misoprostol is a derivative of
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PGE-1
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Standard H2-blocker therapy for mild-duodenal ulcers last
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4-8 weeks
|
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Oxytocin
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is used to treat postpartum hemorrhage
|
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Drugs that bind to the receptor in the cell membrane and increase cAMP concentration include all of the following EXCEPT:
a. ACTH b. isoproterenol c. hydrocortisone d. glucagon |
c. hydrocortisone
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Drugs that promote the release of insulin include all of the following EXCEPT
a. chlorpropamide b. glyburide c. glipizide d. tolamide |
d. tolamide
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Drugs that operate via cytoplasmic receptors include the following EXCEPT:
a. levothyroxine b. dexamethasone c. estriol d. mitotane |
a. levothyroxine
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Which of the following steroids has the LEAST mineralocorticoid potency?
a. fludrocortisone b. hydrocortisone c. cortisone d. beclomethasone |
d. beclomethasone
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Bromocriptine is used to treat some cases of amenorrhea because
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it inhibits prolactin release
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Adverse reactions associated with prednisone include all of the following EXCEPT
a. psychoses b. peptic ulcers c. increased susceptibility to infection d. depression |
d. depression
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Adverse reaction to chlorpropamide include the following EXCEPT
a. water retention b. hypoglycemia c. decreased tolerance to ethanol d. hyperglycemia |
d. hyperglycemia
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Insulin is used
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in emergency treatment of hyperkalemia
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The major adverse effect of glipizide is
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hypoglycemia
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Mechanism of action of sulphonylureas (oral antidiabetic drugs) involve
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blockade of ATP-dependent potassium channels in beta cells
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The insulin preparation with the duration of action of about 36hrs is
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insulin ultralente
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Fludrocortisone is used in the treatment of
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adrenocortical insufficiency
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Topical use of corticosteroids may be instituted in the following diseases EXCEPT:
a. skin disease b. eye disease c. joint disease d. gastrointestinal diseases |
c. joint diseases
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Which of the following statements about methimazol is correct
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it inhibits the peroxidase-catalyzed oxidation of iodine
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