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43 Cards in this Set
- Front
- Back
Under the conditions of hypersplenism erythrocytes are
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sequestered
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Thrombocytopenia may be
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congenital or acquired
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Thrombocytopenia is described as a platelet count below ____________ platelets per cubic millimeter
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150,000
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A 30 year old female presents with hematuria menorrhagia and bleeding gums. She is diagnosed with immune thrombocytic purpura (1TP) The most likely cause is
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antibody destruction of platelets
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A 50 year old female diagnosed with primary thrombocythemia. A blood smear reveals ___________ platelets
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overproduced
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A 52 year old male IV drug user was diagnosed with hepatitis C 5 years ago. He is now experiencing impaired blood clotting. A decrease in which of the following could be the cause
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K
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individuals with liver disease often suffer from coagulation disorders because
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clotting factors are produced in the liver
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a 40 year old female develops disseminated intravascular coagulation (DIC).The most likely cause of this condition is
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sepsis
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The sequence of events in disseminated intravascular coagulation (DIC) is initiated by the release of
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Tissue factor
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In DIC active bleeding occurs after intravascular clotting because
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clotting factors are depleted
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A 22 year old female just delivered a healthy baby girl. She suffered from eclampsia during her pregnancy and on the second postpartum day she complained of bleeding gums bruising on her arms and legs. Hematology lab tests indicate that she has a DIC. Further testing revealed an increase in
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Fibrin degradation products (FDPs)
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A common life threatening complication of a thrombus in a deep vein is
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Pulmonary embolus
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A 1 year old female is diagnosed with anemia secondary to insufficient erythropoiesis. The most likely cause is
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an iron deficiency
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Iron deficiency anemia
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may be related to socioeconomic factors
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A 12 month old toddler weighing 18 pounds is brought to the clinic because of weakness, slow physical growth and developmental delays. His mother reports that the only food he will consume is cows milk. Considering this info the nurse decides that the child probably has
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iron deficiency anemia
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A 16 month old female presents with tachycardia pallor anorexia and systolic murmur. Hemoglobin determination indicates a content below ________ g/dl
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5
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Maternal fetal vlood incompatibility may exist in which of the following conditions
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Mother is RH-negative and fetus is RH- positive
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A 22 year old female gives birth 20 weeks gestation to a stillborn fetus. Physical exam reveals gross edema of the entire body and anemia. this condition is referred to as
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hydrops fetalis
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Sickle cell disease is characterized by the presence of Hb S. Which of the following amino acids is present in Hb S and not present in normal Hb
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Valine
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A 10 year old male is diagnosed with sickle cell anemia. he most likely inherited it from
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both his mother and father
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in the United States sickle cell disease most commonly occurs in
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African Americans
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A 25 year old female has a child that is diagnosed with sickle cell anemia. She does not have the disease. Which of the following characterizes the genetic makeup of the parents with regard to this trait?
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HbS and HbA
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The erythrocytes of a person with sickle cell anemia may become sickled if
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oxygen tension is low
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A 12 year old male is diagnosed with sickle cell anemia =. A blood smear reveals severly sickled celss. The sickled cells will be romoved from circulation mostly by the
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spleen
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A major symptom of vasoocclusice crisis in sickle cell anemia is
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Peripheral edema
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The type of sickle cell crisis seen only in young children is
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sequestration
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A 6 year old male with afatigue jaundice and irritability. A blood smear shows the prescence of sickled cells. Erythropoiesis is compromised in this child resulting in a(n)
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apalastic crisis
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A 5 year old female dies from sickle cell disease. The most likely cause of death is
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infection
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The alpha and beta thalassemias are inherited in an _____ fashion
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autosomal recessive
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A 2 year old male presented with growth and maturation retardation spenomegaly. He died shortly after arriving at the ER. Autopsy revealed thalassemia secondary to defective
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hemoglobin synthesis
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A 38 year old female gives birth a stillborn fetus. Autopsy reveals cardiomegaly heptomegaly edema ascites. The most likely cause is
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alpha thalassamia major
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Hydrops fetalis may result from which type of thalassemia
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Alpha major
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The mother of a 3 year old child speaks to the pediatrician because the child took several hours to stop bleeding following a minor scrape. testing reveals that the child has hemophilia. A resulting froma deficiency in
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Factor VIII
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Hemophilia B is also known as
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Christmas disease
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A 3year old child presents with bruising on the legs and trunk and a petechial rash. the mother also reports frequent nosebleeds. Lab tests reveal a decreased platlet count. The most likely diagnosis is
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idiopathic thrombocytopenis purpura
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A 5 year old male is diagnosed with diagnosed with idiopathic thrombocytic purpura (1TP). This condition is caused by
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virally induced antibody destruction of platelets
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Which of the following clusters of symptoms would lead you to suspect a child has idiopathic thrombocytopenic purpura (1TP)
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Spontaneous nosebleeds bruising petechiae
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A 1 year old is diagnosed with idiopathic thrombocytopenis purpura (1TP). The most serious concern is development of
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intracranial bleeding
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The most common shildhood cancer is
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Acute lymphoblastic leukemia
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A 5 year old male is diagnosed with leukemia. Which of the following symptoms would be expected
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Fatigue
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A 10 year old male with Down syndrome undergoes chemotherapy for cancer. Following treatment he is most susceptible to
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Acute myelogenous leukemia
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A 10 year old femlae is diagnosed with a malignancy in the brain and lung. DNA analysis reveals translocation at chromosome 7 and 14. The most likely diagnosis is
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lymphoblastic non Hodgkin lymphoma
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Which condition increased the rick of developing malignant lymphoma
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AIDS
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