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34 Cards in this Set

  • Front
  • Back

Water mainly is in two parts of the body...

Extracellular- In cells




Intracellular fluids -


Intersticial = Between Cells = Spinal Fluids


Inner vascular = Blood

Functions of water are...

Temperature Regulation


Solvent for Biochemicals


Lubrication


Hydrolysis reactions

Temperature Regulation by water is done to

Metabolic reactions create heat



Lose a lot by radiation as well as evaporation

Heat loss of water by skin

20-30 ml/hr which is about 12-18 kcal/hour

Key parts of water balance is...

Osmosis = The abundant solvent side will go to the solute side

Water balance intake

Fluids (the most), Foods, metabolism

Water balance losses

Kidney (varieable and REGULATED!!!!)


Feces


Lungs


Skin ( The most)



Water AI

3.7 L/d for males


2.7 L/d for females

Osmotic pressure changes as a result of...

Mouth/pharynx dehydration = Thirst


Hypothalamus = Thirst in brain and ADH


Kidney = Blood pressure/Na retention/Water retention

Dehydration leads to

- Loss of extracellular and intracellular fluid and increase osmotic pressure




- Kidneys raise both kinds of fluids

How is blood affected by Renin-Angiotensin System?



4. Blood vessel constriction by angiotensin 2 = increased blood pressure



True or false: Thirst is a good indicator of dehydration

FALSE!!!! First step of being dehydrated

Moderate amounts of dehydration are

Tingling in arms, lagging pace, flushed skin

Dehydration causes include

Diarrhea/vomitting


Diabetes insipidus (ADH deficiency)


Excessive perspiration


Diuretics

Major cation electrolytes in intracellular fluids

Potassium


Magnesium

Major Anions electrolytes in in intracellular fluids

Phosphate


Sulfate

Major cations electrolytes in extracellular fluids

Sodium


Calcium

Major anions in extracellular fluids

Chloride


Bicarbonate

Sodium functions

Water Balance


Acid/base balance


Conduction of nerve impulse (Polarity)


Glucose and other nutrient absorption

Sodium Balance

100% absorption rate


98% conserved b kidney

Sodium AI

1.5 g/d



Sodium UL

2.3 g/d

Aldosterone results in...

Sodium and water retention

ADH results in

More water absoprtion

Increased sodium intake can result in

Hypertension


Hypernatemia


Increased blood volume


Increased blood pressure


Genetic component relationship between Na and Blood Pressure

Potassium Functions

Fluid balance


Muscle Contraction


Nerve Impulse Contraction

Potassium Balance

Larger Sweat losses


Not as well conserved as salt

Potassium AI

4.7 g/d

Potassium Deficiency

Hypokalemia!


- Muscle weakness


- Heart irregularities

Sodium Potassium Pump

1. ATP and 3 sodium ions bind to sites


2. ATP breaks down ADP and P, releasing energy


3. 3 Sodium ions diffuse away


4. Transport protein reverts to original shape

Chloride functions

Acid base balance


HCl in stomach

Chloride AI

2.3 g/d



Chloride UL

3.6 g/d

Chloride food source

Sea salt