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45 Cards in this Set

  • Front
  • Back

Nerve

Many neurons bundled together

Neurons

One nerve cell

3 types of neurons

Sensory- long dendrite, short axon. Carry info from sensory receptor cells to CNS


Motor- short dendrite, long axon. Carry info from CNS to effector


Interneuron- short dendrite, short or long axon. Carry info within CNS

Dendrites

Receive nerve impulse from postsynaptic bulbs and carries nerve impulse to the cell body

Axon

Conducts nerve impulse from cell body to terminal branches

Schwann cells

Type of support cell that wraps around long processes of neurons


Form myelin sheath

Myelin sheath

Inner sheath formed by Schwann cells around long processes


Helps speed up nerve conduction

Neurilemma

Outer sheath


Helps with nerve regeneration

Nodes of ranvier

Gaps in myelin sheath between Schwann cells


Allow for Saltatory conduction (fast nerve impulse conduction)

Saltatory conduction

Very fast nerve impulse conduction where the impulse jumps from node to node

CNS vs PNS

CNS- nerves in spinal chord and brain


PNS- peripheral nervous system, all nerves not in brain or spinal chord

Branches of PNS

Somatic (voluntary)


autonomic (involuntary): parasympathetic (calm/normal) and sympathetic (fight or flight)

What is an action potential

Nerve impulse, an electrochemical change between inside and outside of membrane

Path of action potential

Dendrites , through cell body and along axon towards axon bulb


Moves in wave like motion

Start of action potential

Stimuli causes movement of Na+ and K+ across membrane

Membrane characteristics contributing to action potential

Na/K- pump work continuously to slowly restore Na to outside of membrane and K to inside


Na and K gates- open for short time, molecules move quickly

4 steps of action potential

Resting potential, depolarization, repolarization and refractory period

Resting potential

Neuron CAN accept a stimuli


-65mV


Both Na and K gates closed


More Na outside, more K inside

Depolarization

Neuron CANT accept stimuli


-65mV becomes +40mV


Na gates open, k gates closed


Na moves to inside, no K movement

Repolarization

+40mV becomes -65mV


Na gates closed, K gates open


No Na movement, k moves outside

Refractory period

Stays at -65mV


Both gates closed


More Na inside and K outside, pump must reverse

Synapse

Space between presynaptic and postsynaptic membrane

Neuron to neuron transmission

- Ap is received at axon bulb, Na gates open and Ca also enters axon bulb from synapse by active transport


- Ca++ binds with contractile proteins causing them to shorten, causes synaptic vesicles to be pulled up to membrane


- vesicles open at membrane, releases neurotransmitters (proteins) into synapse


- neurotransmitters diffuse across synapseand bind to receptor sites on postsynaptic membrane


Depending on number of excitatory neurotransmitters, inhibitory transmitters, and presence of drugs, ap may or may not develop on second neuron

Norepinephrine

Excitatory neurotransmitter


Decreases the permeability of postsynaptic membrane causing Na gates to open


Increases chance of ap occurring on neuron 2

Acetylcholine

Inhibitory neurotransmitter


Increase permeability of postsynaptic membrane, causing K gates to open


Decreases chance of ap occurring on neuron 2

How and why are neurotransmitters broken down after being released in synapse

So they don’t interfere with future ap or cause 2nd neuron to fire an ap at random


Monoamine oxidase breaks down norepinephrine


Acetylcholinesterase breaks down acetylcholine

Autonomic branch of PNS

One set of sensory neurons and 2 sets of motor neurons taking ap out


Results in swelling of mixed nerve where cells bodies of second motor meet.


Swelling called ganglion. It’s location separates parasympathetic branch and sympathetic branch

Parasympathetic vs sympathetic branches of autonomic branch

Parasympathetic: relaxed state, acetylcholine, spinal nerves enter spine at cranial-sacral region, long pre-ganglionic fibers, short post-ganglionic fibers


Sympathetic: fight or fight, norepinephrine, spinal nerves enter at thoracic-lumbar region, short pre-ganglionic fibres , long post-ganglionic fibers

What happens when sympathetic branch fires

Increased heart rate, blood pressure, respiration, ATP production


Increases blood flow to skeletal muscles, decreases to digestive organs


Muscles tense


Senses heightened

Reflex arc

Part of somatic branch


Allows faster response to dangerous situation by bypassing brain

Hypothalamus

Control centre where nervous system and endocrine system meet


Receives neurotransmitters from brain then takes one of two pathways


1) releases hormones into blood, stimulates anterior pituitary to produce and release own hormones into blood


2) uses nerve to stimulate posterior pituitary to release hormones already produced in hypothalamus

Cerebrum function

Interprets touch, vision, emotions etc

Thalamus function

Relay motor and sensory signals to cerebral cortex

Copus callosum

Bridge between left and right side of brain

Cerebellum function

Regulates motor movements

Grey vs white matter in brain

Gray: location of all synapses, contains cell bodies, dendrites , axon terminals


White: non-functional, acorns connecting different parts of gray matter

When will an ap fire in neuron 2

If sum of all excitatory and inhibitory responses is above the threshold of -50mV

Spatial summation

Multiple neuron 1 releases neurotransmitters into one neuron 2

Temporal summation

One neuron 1 releases neurotransmitters repeatedly onto neuron 2

All or none law

The neuron either fires at maximum intensity or not at all


Not followed by a nerve, only individual neurons

Mixed nerves

Dendrites of sensory neurons and axons of motor neurons

Cranial nerves

Enter CNS at brain


sensory, motor, or mixed nerves found here

Spinal nerves

Enter CNS at spinal cord


Mixed nerves only

Sensory nerves vs motor nerves

Sensory- dendrites of sensory neurons


Motor- axons of motor neurons

Somatic branch of PNS

Have one set of sensory neurons bringing ap into spinal cord and one set of motor neurons taking ap out