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13 Cards in this Set
- Front
- Back
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Drugs to avoid in renal failure |
Tetracyclines Nitrofurantoin NSAIDS Lithium Metformin |
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Drugs that need dose reduction in renal failure |
Penicillins, vancomycin, streptomycin, cephalosporins, gentamicin. Digoxin Atenolol Methotrexate Sulphonylureas Furosemide Opioids |
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Drugs that are safe in renal failure |
Rifampicin Warfarin Erythromycin Diazepam |
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eGFR Variables |
Creatinine
Age Gender Ethnicity |
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CKD Classification |
1) GFR > 90 with some signs of kidney damage on other tests. 2) GFR 60-90 with some signs of kidney damage on other tests. 3a) GFR 45-59. 3b) GFR 30-44. 4) GFR 15-29. 5) GFR < 15. |
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Acceptable changes in renal function when starting ACEi |
Decrease in GFR of 25 % Rise in creatinine of 30 % |
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Target Hb in CKD |
10-12 Normochromic normocytic anaemia Consider when GFR < 60, apparent when < 35 |
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Screening for autosomal dominant polycystic kidney disease (ADPKD) |
Ultrasound |
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Diagnostic criteria For ADPKD |
Positive family history. If < 30 years - 2 cysts unilateral or bilateral 30-59 years - 2 cysts in each kidney > 60 years - 4 cysts in each kidney |
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Interpretation of ACR results |
If not diabetic - > 30 - clinically singificant - if < 70 repeat test. If diabetic - >2.5 for women and 3.5 for men. |
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Factors effecting GFR |
Extremes of muscle mass Pregnancy Eating a large amount of red meat in preceding 12 hours |
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Haematuria referral guidelines |
Any age and painless macroscopic haematuria > 40 years and recurrent/persistent UTIs with microscopic haematuria > 50 years and unexplained microscopic haematuria |
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Nephrotic syndrome causes |
Renal - minimal change glomerulonephritis, mebranous glomerulohephritis, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis. Systemic - DM, SLE, amyloidosis Drugs - gold, penicillamine Congenitial, neoplasia, infection |
