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50 Cards in this Set

  • Front
  • Back

Functions of muscular tissue

Produce body movements


Maintain posture


Heat production


Protection

Skeletal muscular tissue is attached to ____ by _____

Bone by tendon

Microscopic feature of skeletal muscular tissue

Striated


Long


Cyclindrical


Unbranched


Peripherally located nuclei

Skeletal muscular tissue nervous control

Somatic nervous system - voluntary

Skeletal muscles arise from

Fusion of hundred or more my oblast during embryonic development

Satellite cells

Part of myoblast that does not fuse or differentiate but remains mesenchymal cells


Located on the external surface of muscle fibers inside the developing external lamina


Proliferate and produce new muscle fibers following muscle injury

Skeletal muscle fiber length

Very long, vary greatly


Few centimeters to 30-40 cm

Skeletal muscle fiber diameter

Very large 10-100 um

Transverse t tubules

Long invaginations in the sarcolemma that penetratate into the sarcoplasm


Aligned with each A-I band junction


Filled with interstitial fluid


Ensures action potential to excite the whole muscle fiber at the same instant

Nuclei skeletal muscle

100 or more


Found beneath sarcolemma


Glycogen

Large molecule composed of many glucose molecules


Can be used for ATP synthesis

Myoglobin

Red colored protein


found only in muscle


Binds O from interstitial fluid


Releases O needed by the mitochondria for ATP synthesis

Mitochondria

Lie in rows throughout fiber


Close to contractile muscle proteins

Sarcoplasm reticulum

Fluid filled system of membranous sacs which encircle each myofibril


Dilated end sacs called terminal cisterns butt against T tubules at both sides


Abundant in skelatal muscle fiber


Relaxed - store Ca


Release of Ca ions triggers muscle contraction

Mtofibrils

Contractile organelles of skeletal muscle


Arranged in parallel bundles


2um in diameter and extend the entire length of a muscle fiber


Contain thick and thin filaments

Sarcomere

Basic functional unit of myofibril

Z disc

Narrow


plate shaped regions of dense material


Separate one sarcomere from the next

A band

Dark middle part of sarcomere


Extend the entire length of thick filaments


Includes part of thin filaments that overlap thick filaments

I band

Lighter less dense area


Contains remainder of thin filaments


Z disc passes through center

H zone

Narrow region in center


Contains thick and no thin filaments

M line

Region in center of H zone


Contains proteins that hold thick filaments together


Epimysium

Outer layer


Entire muscle


Dense irregular connective tissue

Perimysium

Separates 10 to 100 muscle fibers


Groups into fascicles


Dense irregular collagenous connective tissue

Endomysium

surrounds individual muscle fiber


Reticular fibers

Myosin

Thick filament


Tail and two myosin heads


Motor protein

Actin

Thin filaments


Myosin binding site


Motor protein

Regulatory protein

Help switch contraction on and off

Tropomyosin

Component of thin filaments


Covers Myosin binding site when relaxed


Troponin

Thick filament

Structural proteins

Keep thick and thin in proper alignment


Give elasticity and extensibility


Link myofibril to sarcolemma and extracellular matrix

Titin

Connects z disc to M line


Stabilize thick filaments


Stretch and spring back unharmed


Accounts for extensibility and elasticity of myofibril

Alpha actinin

Protein of z disc


Attaches to actin molecules and to titin molecules

Myomesin

Forms M line


Binds titin


connects adjacent thick filaments

Nebulin

Wraps around thin


Anchor thin to z discs


Regulates length of thin during development

Dystrophin

Link thin filaments to integral proteins of sarcolemma


Reinforce sarcolemma


Transmit tension to tendons


Location of cardiac muscle

Heart and large vessels attached to heart

Microscopic features of cardiac muscle

Branched cylindrical


Uni or binucleated


Centrally located nucleus


Striated


Intercalated discs

Cardiac muscle fiber length

Long 50 to 100 um

Cardiac muscle diameter

Large 10 to 20 um

Intercalated discs

Contain gap junctions and desmosomes

Cardiac muscle structure

Larger t tubules found at z lines


Sarcoplasmic reticulum less developed

Connective tissue of cardiac muscle

Endomysium


Subendocardial and subpericardial ct

Location of smooth muscle

Walls of hollow viscera


Airways


Blood vessels


Iris


Cillary body of eye


Arrector pili of hair follicles

Microscopic features of smooth muscle

Fusiform


Spindle shaped


not striated


Centrally located nucleus

Motor control of smooth muscle

Autonomic


Involuntary

Length of smooth muscle fiber

Intermediate


30 to 200 um

Diameter of smooth muscle

Small


3 to 8 um

Structure of smooth muscle

No regular pattern of overlapping


Actin and Myosin form lattice and insert into dense bodies in the sarcoplasm


Gap junctions allow ionic communication


No t tubules


Very little SR


Caveolae


Regulatory proteins of smooth muscles

Myosin light chain kinase


Calmodulin

Connective tissue of smooth muscle

Endomysium and less organizer CT sheaths