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14 Cards in this Set
- Front
- Back
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Adaptive immunity
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adapts to a specific microbial invader or a foreign substance
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Humoral immunity
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Immunity brought about by antibodies that are produced by B cells.
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Monomer
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Bivalent antibody: has four (4) protein chains.
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Variable (V) regions
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Two sections located at the ned of the Y's arms; these bind to the epitopes
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Constant (C) region
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the stem of the antibody monomer and lower parts of the arms of the Y; Five (5) types of C regions
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The five (5) classes of Igs (Immunoglobulins)
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IgG, IgM, IgA, IgD, IgE
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IgG
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Confer passive immunity to a fetus, protrct against circulating bacteria, ans viruses, neutralize bacterial toxins, trigger the complement system, and when bound to antigens, encance the effectivness of phagocytic cells. Most abundant in SERUM
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IgM
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Pentamer structure consisiting of 5 monomer held together by a polypeptide. Remains in the blood vessels without entering the surrounding tissues. Predominant type of antibody involved on the surface of the red blood cells.
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IgA
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The most common form in mucus membranes and in body secretions such as, mucus, saliva, tears, and breast milk. Prevents the attachment of microbial pathogens to mucosal surfaces, this is important in resistance to intestinal and respiratory pathogens. Most abundant in the BODY.
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IgD
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Found, in blood, lymph, and particularly on the surface of B cells.
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Strength of the bond between an antigen and an antibody.
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Affinity
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Antibodies cause antigens to clump together
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Agglutination
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Antigen is coated with antibodies that enchance its ingestion and lysis by phagocytic cells
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Opsonization
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Resembles opsonization in that the target organism becaomes coated with antibodies; however, destruction of the target cell is by immune system cells that remain external to the target cell
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Antiboby-dependent cell-mediated cytotoxity
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