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20 Cards in this Set

  • Front
  • Back

Cancer of the lymphatic system and the lymph nodes. These are malignant cells that forms into mass.

Lymphoma

2 types of lymphoma

Hodgkin


Non-hodgkin –- most common

Etiology of lymphoma

In hodgkin lymphoma – the cancer usually affect one lymph node after another in order.


In non-hodgkin lymphoma – tumors may arise in different lymph nodes, skipping some node

Risk factors for hodgkin lymphoma

Ages between 15 and 34 years and over 55 years


Common in men


Common in U.S, Canada, Northern Europe


Siblings, twins


Affluence


HIV

Risk factors for non-hodgkin lymphoma

Age 60 and older


White american


Gender


Radiation and chemicals


Immunodeficiency


Infection


Breast implants


Body weight and diet

Curable form of lymphoma

Hodgkin's lymphoma

Signs & symptoms of hodgkin's lymphoma

swollen lymph nodes


Cough and shortness of breath


Fever


Tiredness


Weight loss


Itchy skin

Diagnosis for hodgkin's lymphoma

lymph node biopsy – surgeon remove all or part of an enlarged lymph nodeStaging

Subtypes of hodgkin lymphoma

Classical Hodgkin Lymphoma – 95% of patient have this type


- Nodular sclerosis


- Mixed cellularity


- Lymphocyte depleted


- Lymphocyte- rich classical


Nodular Lymphocyte- predominant Hodgkin Lymphoma

Tx of hodgkin lymphoma

Chemotherapy

Absence of this type of cell is a characteristic of non-hodgkin lymphoma

reed- sternberg cell

A condition which is a result of genetic mutation, and divide uncontrollably being neoplastic cells.

Non-hodgkin lymphoma

Types of non-hodgkin lymphoma

According to site:


Nodal lymphomas – found in the lymph nodes


Extranodal lymphoma – found in other tissue or organs



B-cell Lymphoma:


Diffuse large B cell Lymphoma – most common and is aggressive


Follicular lymphoma – indolent lymphoma, caused by translocation of Chromosome 14 and chromosome 18. causing blocked cell death.


Burkitt lymphoma – highly aggressive lymphoma, from chromosal translocation. Increased cell division.


Mantle cell Lymphoma- aggressive lymphoma, chromosomal translocation between 14 and 11. cell growth


Marginal zone lymphoma – indolent lymphoma.


---Common type is Mucosa Associated Lymphoid tissue – lining of the stomach



T-cell lymphoma:


Adult t-cell lymphoma – caused by t- lymphoytopic virusMycosis fungoides – t-cell lymphoma of skin. Has ‘’cerebriform” nucleus.

This virus infects lymphocytes , incorporates DNA into the host DNA.

Epstein Barr virus

Indolent type of lymphoma that produce M proteins causing blood gets thick and viscious

Lymphoplasmacytic lymphoma

Condition in which M proteins cause blood to get thick and viscious

Waldenstrom macroglobulinemia.

Types of T-cell lymphoma


Types of T-cell lymphoma

Adult t-cell lymphoma – caused by t- lymphoytopic virus


Mycosis fungoides – t-cell lymphoma of skin. Has ‘’cerebriform” nucleus.

Types of B-cell lymphoma

Diffuse large B cell Lymphoma – most common and is aggressive


Follicular lymphoma – indolent lymphoma, caused by translocation of Chromosome 14 and chromosome 18. causing blocked cell death.


Burkitt lymphoma – highly aggressive lymphoma, from chromosal translocation. Increased cell division.


Mantle cell Lymphoma- aggressive lymphoma, chromosomal translocation between 14 and 11. cell growth


Marginal zone lymphoma – indolent lymphoma.---Common type is Mucosa Associated Lymphoid tissue – lining of the stomach

Symptoms of non-hodgkin lymphoma

Diagnosis & Tx of non-hodgkin lymphoma