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55 Cards in this Set

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Four limbic functions

Homeostasis, memory, emotions, olfaction
What is the pathway for the Papez circuit?
Subiculum-> fornix -> mammillary nucleus and tract -> anterior thalamic nucleus -> internal capsule -> cingulate gurus -> parahippocampal gyrus -> entorhinal cortex.
Structures implicated in: declarative memory loss
Bilateral medial temporal lobe or bilateral medial diencephalon
Structures implicated in: habit learning
Caudate nucleus. May be linked to OCD. Variety of other structures
Structures implicated in: working memory
Dorsolateral prefrontal areas
Vascular territory most likely to cause memory deficit
ACA, damaging basal forebrain and maybe medial diencephalon
Wernicke-Korsakoff syndrome
Caused by thiamine deficiency, seen in alcoholics usually. Bilateral necrosis of mammillary bodies and other medial diencephalic and periventricular nuclei. Triad of ataxia, abnormal eye movement! And confusional state. Can result in coma.nsurvivors left with anterograde and retrograde amnesia, frontal lobe dysfunction, confabulation
Effect of ablation of amygdala bilaterally
Placid
Kluver-bucy syndrome
Seen rarely in humans. Placid behavior with other symptoms
Septal area
Pleasure area
Two main types of seizures
Partial, generalized
Typez of partial seizures
Simple, complex, partial with secondary generalization
Types of generalized seizures
Absence, myoclonus, clinic, tonic, tonic-clonic, atomic
Which type of seizure involves loss of consciousness?
Complex partial
Prevalence rate of febrile seizures
3-4%
Percentage of children who remit spontaneously from absence seizures
40%
First line of treatment of epilepsy in adults
Carbamazepine (tegretol), phenytoin (Dilantin)
First line of treatment of seizures in children
Ethosuximide (zarontin)
Medically refractory epilepsy: prevalence
20-30%
Medically refractory epilepsy: treatments
Ketogenic diet, vagal nerve stimulators, esurgery
Most common type of seizure
complex partial (65% of all epilepsy pts)
Auras do not occur with:
Generalized seizures
Other name for petit mal seizure
Abscence
Name the seizure: Brief, single symmetrical jerks of head and upper extremities; in series or clusters, common after waking
No LOC (duration of generalized polyspike-wave burst usually <1 second)
Myoclonic

Name the seizure:Abrupt loss of muscle tone that produces a sudden fall

Atonic
Landau-Kleffner
“Acquired aphasia with convulsive disorder”
need abnormal EEG (usually over temporal areas) but no actual seizures are necessary for diagnosis
Age of onset b/t 2 and 11; follows a period of normal development
Characterized by sudden or gradual onset of auditory agnosia; may involve total unresponsiveness to language or progressive deterioration of expressive speech
Usually associated with behavioral difficulties as well
Seizure type varies, but most common is generalized motor seizures
Seizures and language deficits unresponsive to AED’s (current: steroid tx)
Earlier onset is related to poorer prognosis
Rolandic epilepsy
believed to have autosomal dominance with incomplete penetrance
EEG has characteristic centrotemporal spikes
onset b/t 3 and 13; remission nearly always complete by age 15
Characteristics: unilateral parasthesias, speech arrest, T-C seizures occurring mostly at night
visual regions of temporal lobes
inferotemporal cortex
separates superior and middle temporal gyri and contains neocortex
superior temporal sulcus
the gustatory cortex and auditory association cortex
insula
limbic cortex, amygdala, hippocampal formation
subcortical temporal lobe structures
stimulus recognition
hierarchical sensory pathway
directs movements with respect to auditory info
dorsal auditory pathway
stimulus categorization
polymodal pathway
crucial to long term memory...hippocampal projection forms PERFORANT PATHWAY
medial temporal projection
movement control, short term memory and affect
frontal lobe projection
processing auditory input, visual object recognition, long term storage of sensory input (memory)
temporal lobe function
process of matching visual and auditory info (depends on STS)
cross modal matching
'theory of mind' ...develop hypotheses about other people's intentions
social cognition
upright faces processed in a separate face perception system
Thatcher illusion
early perception of facial features
inferior occipital gyri
invariant aspects of faces, perception of unique identity
FFA
perception of eye gaze, expression, and lip movement
STS
personal identity, name and bio info
anterior temporal sulcus
prelexical speech perception
auditory cortex
spatially directed attention
intraparietal sulcus
emotion
amygdala, insula limbic system
speech sounds come from 3 restricted ranges of frequencies
formants
magnitude of a sensation as judged by a given person...decibels
loudness
distinctive character of a sound
timbre
the position of a sound in a musical scale...vibration rate of a sound wave
pitch
primary auditory cortex
Heschl's gyrus
disturbance of auditory sensation and perception, music perception, visual perception...impaired long term memory, altered personality and affective behavior/sex behavior
symptoms of temporal lobe lesions
disturbed recognition of words ....
word deafness– inability to recognize words as such despite intact hearing of pure tones
Wernicke's aphasia
amnesia for all events after the surgery/accident

anterograde amnesia