Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
most potent negative ionotrope of all CCBs?
|
Verapamil
|
|
what type of CCBs bind more selectively to vascular smooth muscle and therefore relax smooth muscle at a conc that produces almost no negative inotropy?
|
Dihydropyridines
Nifedipine, amlodipine, etc |
|
What type of CCB would you choose for HTN, prinzmetal angina, vasospam after SAH?
|
Dihydropyridines
Nifedipine, amlodipine, etc |
|
What type of CCB would you choose for HTN, rate control in a flutter/fib, and to abolish SVT
|
Verapamil or Diltiazem
|
|
most serious effects of CCB tox?
|
Myocardial depression and peripheral vasodilitation
hypotension is most common physiologic abnormality after OD |
|
adults receiveing long term therapy with CCBs can develop hypotension, brady, or cardiac conduction abnormalities if they ingest how much of their daily dose
|
two times their daily dose
|
|
symptoms of BB OD and CCB OD can be very similar, what lab can help you distinguish?
|
CCB: Hyperglycemia
BB: Hypo/euglycemia |
|
Hypotesni, bradycardia, and AV block can be seen in other conditions than CCB tox. What is your DD for these sx?
|
Hypothermia
ACS Hyperkalemia Cardiac glycoside tox (dig) BB Antiarrhythmic class IA-C tox Central alpha agonist (clonidine) tox |
|
if digoxin tox is a potential issue in a pt with suspected CCB tox, the clinician may reasonably avoid the of use what treatment
|
Calcium
there is potential worsening tox |
|
decreased level of consciousness following CCB ingestion is a result of what
|
cerebral hypoperfusion or coingestion
|
|
when should pacing be used in a pt with CCB OD?
|
HR < 30
|
|
life threatening tox can be seen with ingestion of just ONE tablet of which CCB in KIDS?
|
Verapamil
so you should use activated charcoal on them if its an adult the evidence is lacking for the use of activated charcoal |
|
what therapy should be considered for patients with large ingestion of sustained release agents?
|
Whole bowel irrigation
|
|
which type of calcium is preferred in CCB tox tx? (Ca Chloride or Ca Gluconate?)
what is the side effect of this drug if not administered properly? |
Calcium Chloride
must give through central line if given through peripheral IV can cause severe soft tissue necrosis |
|
What is important to remember when giving Ca as a tx for CCB tox?
|
the effect may be transient
repeat dosing is commonly required or you can use an infusion of 2-6 g hypercalcemia is acceptable in pts who are not responding |
|
Patients with CCB tox who do not respond to Ca admin or who require repeated doses are usually given what?
|
Adrenergic agonists
|
|
if a pt doesnt respond to vasopressor therapy in CCB tox, what should be used
|
hyperinsulin/euglycemia therapy
aka about 1 unit/kg with 50mL of 50% detrose |
|
tx of choice for BB OD?
|
Glucagon
bypass the B adrenergic receptor and stimulated cardiac activity |
|
what therapy should be strongly considered prior to administering glucagon?
|
ET Intubation
because the major side effects are vomiting and hyperglycemia |