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17 Cards in this Set

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Define what a vaccine is

A material originating from a micro organism or other parasite that induces an immunological mediated resistance to disease

Milk maids didn't get small pox! What is the name and year of the person who looked further into this what did he do?

Edward Jenner 1796- found that milk ladies were exposed to cows with cow pox which helped them become immune to small pox

What Is either side of the window of opportunity

1. Loss of passive immunity from mother


2.timing of natural exposure to infection

Which is the most effective and induces a cell mediated response?

Live vaccines

What is pertussis and how long does your maternal passive immunity last (generally)

Declines rapidly

What does this graph show?

Seroresponders are people that have detected the antigen and started to produce their own antibodies. You can see that ideally 100% would be seroresponders at 11-12 months there is the highest %. This could be due to this being the 'Window of opportunity' for the children

Are their benefits of curcumin to infectious diseases in childhood?

Yes there seems to be a lower likelihood of allergy and auto immune disease e.g. asthma

Why is it best to get diseases such as chicken pox when you are younger?

You have a weakened cell mediated response to infection so less immunopathology

What is herd immunity?

Not needing to vaccinate the entire population but a large enough % so that it cant spread

What does EPI stand for and what was its goal by 1990 (starting at 1974)

The expanded programme on immunization. Vaccines for every child against 6 major diseases

EPI failed its initial targets. Name some barriers they came across

1. Lack of public and government awareness on the seriousness of some of the diseases


2. Bad programme management


3. Inadequate equipment and skills for vaccination storage and handling

What is a more current vaccine plan that is still going today

Is measles bacteria or virus and enveloped or non enveloped?

Enveloped Virus

What is the difference between humoral and cellular immunity?

What is the Dosage, number of doses, duration of immunity, cell mediated response level and risk of reversion to virulence for live attenuated vaccines

Low dose, only 1 dose, long lived immunity, good cell mediated response and rarely reverts back to virulence

What %of people need to be vaccinated to create herd immunity for measles?

93-95% this is quite high

Does the uk have herd immunity?

No