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18 Cards in this Set
- Front
- Back
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Pelger-Huet Anomaly/Pince-Nez Cell
Benign congenital hypo segmentation of PMNs. |
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Alder-Reilly Inclusions/Anomaly
Hematological manifestation of a group of inherited recessive disorders. Deficiency in enzymes to break down mucopolysaccharides. Hurlers syndrome. |
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Toxic Granulation
Stimulation of granulocytic cells results in fewer mitotic divisions. Prevents normal dilution of nonspecific granules. Severe bacterial infection or toxicity. |
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Chediak Higashi Syndrome
Rare autosomal recessive disorder, giant lysosomes in most cells of body. Abnormally formed lysosomal granules in WBC. Decreased platelets with abnormal large granules and defective function. |
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Gaucher's Disease or Gaucher's Cell
Inability to degrade glucocerebroside. Deficient beta-glucocerebrosidase. |
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Pyknotic Degeneration
Cells undergoing apoptosis. Nuclear material loses chromatin pattern. |
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May-Hegglin Anomaly
Hematological manifestation. Rare autosomal dominant condition. Dohle like bodies not RNA. |
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Flame Cell
Plasma cell producing IgA. Brilliant red staining cytoplasm from IgA. |
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Septicemia
Bacteria in blood. |
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Barr Bodies
Extra X-chromosome unnecessary for normal nuclear function. |
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Toxic Vacuoles
Clear holes in cytoplasm of phagocytic cells. Toxic is increased vacuolization-more than normal. Severe bacterial infections or toxic states. |
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Reactive Lymph
Activated T Lymph. Viral infections. |
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Hyper-segmentation
Congenital or megaloblastic change. |
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Dohle Bodies
Remnant RNA. Toxic granulation, toxic vacuoles, shift left. |
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Foam Cell
Niemann Pick Disease. Inability to degrade sphingomyelin, accumulates in spleen, liver, lungs, brain, BM. Deficient enzyme, sphingomyelinase. |
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Smudge Cell
Cells destroyed making peripheral smear. Increased cell fragility. Can add albumin. |
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Russel Bodies/Mott Cell
Bright red or white globular inclusions of Ig in cytoplasm. |
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Tay-Sachs Disease
Accumulation of un-metabolized ganglioside in almost all tissues. Deficient enzyme, hexosaminidase A. |