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26 Cards in this Set

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3 coat composing the tissue in blood vessel wall

-tuna intima


-tuna media


-tuna adventitia

simple squamous epithelium lining the blood vessels

tuna intima

composed of smooth muscle and elastic fiber

tunica media

composed of fibrous connective tissue that contains autonomic nerve endings



-small network of blood vessels that supply nutrient to the tissues of the wall

tunica adventitia

distributing blood vessels that LEAVE the heart

Arteries

Aalis

collecting blood vessels that RETURN to the heart

Veins

VAVALIK

specialized type of capillaries found in locations such as the bone marrow, spleen and liver

Sinusoids

inhibits platelet activation

Prostacycline (prostaglandin I)

activates platelet

Thromboxane A2

Stimulate vasodilation (widening of blood vessel lumen)

Adenosine

bind thrombin and reduces its ability to participate in the clotting process

Thrombomodulin (TM)

Inactivate factor Va and VIIIa

Activated protein C

an antifibrinolytic enzyme

TAFI

weakly enhances antithrombin (previously called antithrombin III)

heparin sulfate

aka fibrinolysin


function: dissolves clot

plasmin

activate plasminogen to produce plasmin

tissue plasminogen activator

transporter of Factor VIII

vWF

-aid in platelet adhesion


-acts as a carrier protein for factor VIII

vWF

site of synthesis of vWF

-endothelial cells


-megakaryocytes

site of storage of vWF

-weibel -Palade bodies


-alpha granules

A disintegrin and metalloproteinase with a thrombospodin type 1 motig, member 13

ADAMTS 13

where is ADAM 13 synthesized

LIVER

pathological formation of blood clots in veins or arteries that obstruct blood flow

Thrombosis

deficiency of ADAMTS-13

Thrombotic thrombocytopenic purpura

vWF in weibel palade bodies

Ultra long vwF

Cleaves ultra long vWF

ADAMTS 13