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53 Cards in this Set
- Front
- Back
Define the physiological process of cough. The three phases. |
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Clinically define cough. |
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Draw this. |
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Draw this. |
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Define acute cough, subacute cough, and chronic cough. |
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What are the two major types of cough? |
Productive and non-productive |
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Define productive cough. What does each color of secretion imply? Clear, purulent, yellow, and malodorous |
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Define non-productive cough. What are some possible causes of a non-productive cough? |
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What are some complications of cough? |
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What are some non-pharmacologic treatments for cough? |
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ANTITUSSIVES: What are the drugs of choice of non productive coughs? Systemic agents (3) and topical agents (2)? |
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EXPECTORANTS What is the drug of choice for productive cough with thick secretions? |
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Dextromethorphan: Active ingredient in which cold medicine? What is the mechanism of action? Metabolized how? Opiod or nonopiod? Onset and duration? Is it safe? |
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What are some side effects of dextromethorphan? |
General AEs |
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Who's should not take dextromethorphan? |
Obvious stuff, be careful taking ANY drugs that raise serotonin levels |
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Diphenhydramine: Drug type? Mechanism? Antitussive effects? Onset and duration? When used? |
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Side effects and contraindications of diphenhydramine? |
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Codeine (3-methylmorphine):
Drug type? Mechanism? Onset, duration? Metabolism? |
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Side effects of codeine (3-methylmorphine): |
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Contraindications of codeine (3-methylmorphine): |
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How are the topical agents applied? Look over slide. |
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Guaifenesin (Mucinex): What is it used for? Drug type? Used for chronic cough? How does it work? FDA approved? |
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Side effects of guafenesin (mucinex)? Contraindications? |
Hypersensitivity |
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What the hell? |
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What are nasal decongestants? Do they affect release of histamine or any mediators involved in the allergic reaction? What are they commonly formulated with? |
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What is the mechanism of action of nasal decongestants? What type of agonist? What do they stimulate? What three things does this decrease? |
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Difference dosage forms of nasal decongestants?
Two different types of oral decongestants? |
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How does pseudo ephedrine act primarily? What does it stimulate? What is it rapidly metabolized by? Where? |
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What is PE metabolized to a minor extent by? Does it have a better bioavailability than phenylephrine? |
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What are some of the major side effects of systemic decongestants (think about what they are acting on = alpha adrenergics)? |
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What are some precautions and contraindications for PE? |
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Look over. |
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What are the three types of topical nasal decongestants? What is an example of a spray? When is it preferred? |
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What is another spray type (don't give it to meth heads!)? |
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Some advantages of sprays? Disadvantages? |
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Some advantages of drops? Disadvantages? |
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Two drugs types for inhalers? |
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What do mucolytics promote? When are they used? Which diseases? |
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What is mucus? What makes up backbone? What makes side chains? What holds it together? Intramolecular bond type and intermolecular bond type? |
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Look over. |
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How do you facilitate mucus clearance (goals)? water, causes, clearance, inflammation |
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What do bland aerosols do? What are they also known as? What are some difference types (4)? |
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What are the three types of expectorants? Function of each? |
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Commonly used mucolystics: 1. N-acetyl cysteine. Mechanism? How given? Other effects? |
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Side effects and precautions with N-acetyl cysteine? |
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Additional side effects and precautions of n-acetyl cysteine? (mucus production, antibiotics, general, any smells, storage) |
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Mucolytic: 2. Sodium bicarbonate Mechanism? How administered? What does pH increase do? Is it irritating? |
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Mucolytic: 3. Dornase alfa (pulmozyme) Mechanism? Composition? Effects?
Indications? (diseases) Does it have an effect on non-infected sputum? |
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Side effects of dornase alpha (pulmozyme)? Contraindications? |
Contra: In patients hypersensitive to Chinese Hamster Ovary cell products |
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Mucolytics: 4. Amiloride
Mechanism? Drug type? When given? Why given for CF? Prevents what? Other uses? Administration? |
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Mucolytics: 5. Denufosol Tetrasodium
Mechanism? What type of drug is it? |
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