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45 Cards in this Set
- Front
- Back
which of the following hormones is often decrease by approx 25% in the serum of pregnant woman who have fetus with Down's syndrome
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estriol (E3)
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the syndrome of inappropriate antidiuretic hormone secretion (SIADH) causes
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low serum electrolytes
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select the hormones that is ass w/ galactorhea, pituitary adenoma & amenorrhea
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prolactin
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Zollinger Ellison (ZE) syndrome is characterized by great (eg 20 fold) elevation of
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Gastrin
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which statement about mx endocrine neoplasia (MEN) is true
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it is ass w/ hyperplasia or neoplasia of at least 2 endocrine organs
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select the main estrogen produced by the ovaries and use to eva ovarian functions
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estradiol (E2)
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which statement best describes the relationship betwn luteinizing hormone (LH) and FSH in cases of dymenorrhea
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both hormones normally peaks 1 - 2 days before ovulation
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when pituitary adenoma is the cause of decrease estrogen production, an increase of which hormones is most frequently responsible
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prolactin
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which of the following statement is correct in assessing GH defncy
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pituitary failure may involve one, several, or all adenohyprophyseal hormones, but GH defncy is usually found
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which statement best describe the level of GH in patient with pituitary adenoma ass w/ acromegaly
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some pat req a glucose suppression test to test a diagnosis
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hyperparathyroidism is most consistently ass w/
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hypophosphatemia
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PTH levels diff primary and secondary cause by
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hypocalcemia
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the best method of analysis for serum PTH inv using antibodies that detect
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both the amino terminal fragment & intact PTH
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which of the following is most often elevated in hypercalcemia ass w/ malignancy
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PTHRP - parathyroid hormone related proteins
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steriods w/ a dihydroxyacetone group at C17 are classified as
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17 hydroxycorticosteroids
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which statement below regarding adrenal cortical dysfunction is true
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Cushing's syndrome is ass w/ glucose intolerance
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which of the following statement about cortisol in Cushing's syndrome is true
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24 hour urinary free cortisol is a more sensitive test than plasma total cortisol
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which of the following disease is characterized by primary hyperadpsteronism caused by adrenal adenoma, carcinoma or hyperplasia
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Conns disease
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which of the following is the most common cause of Cushing's syndrome
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overuse of corticosteroids
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which of the following is the mechx causing Cushing's disease
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excess secretion of pituitary ACTH
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in which situation is the plasma or 24 hour urinary cortisol not consistent w/ the clinical picture
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eva of congenital adrenal hyperplasia
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which test is used to distinguish Cushing's disease (pituitary Cushings) from Cushing's syndrome caused by adrenal tumors
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serum ACTH
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which is the most widely used screening test for Cushing's syndrome
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overnight deamethasone suppression test
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which test is the most specific for est a diagnosis of Cushing's disease (pituitary Cushing's)
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petrosal sinus sampling following corticotropin releasing hormone stimulation
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primary & secondary Addisons dz can often be diff by
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plasma ACTH
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which of the statement below regarding the catecholamines is true
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plasma levels show both diurnal & pulsed variation
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which assay using 24 hour urine is considered the best single screen testing for pheochromocytoma
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metanephrines
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which metabolite is most often increased in carcinoid tumors of the intestines
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5- hydroxyindolacetic aid (5-HIAA)
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which statement regarding the mz of urinary catecholamines is true
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24 hours urinary catecholamine assay avoids pulse variation ass w/ mzment of plasma catecholamines
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which method used to mz catecholamines is the LEASE specific
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mzment of fluorescence following oxidation by potassium ferricyanide
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which statement about sample collection for catecholamines & metabolites is true
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24 hours urine creatinine should be mz w/ vanillylmadelic acid, homovanillic acid or metanephrines
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which statement below applies both mzment of VMA and meanephrines in urine
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both can be mz by specific HPLC and GCMS assays
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urinary HVA is most often assayed to detect
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neuroblastoma
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thyroid hormones are derived from an amino acid
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tyrosin
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T3 is about ___ ___ ___ than T4
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tenfold more active
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total T3 and T4 are influenced b the level of ___ ___ ___
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thryoxine binding globulin
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which of the following condtx increases total T4 by increasing thyroxine binding globulin (TBG)
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pregnancy or estrogen
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select the most appropriate single screening test for thyroid disease
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Total T4
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the serum TSH level is decreased in
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primary hyperthyroidism
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which assay i most specific & sensitive test for diagnosing thyroid disease
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thyrotropin releasing hormone (TRH_ stimulation test
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which of the following statement is true regarding revere T3 (rT3)
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formed in the blood by degradation of T4
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a pat has:
elevated serum T3 and free T4 very low serum TSH what is the likely cause |
primary hyperthyroidism
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a serum thyroid panel reveals
increase in Total T4 normal TSH normal Free T4 what is the likely cause |
euthyroid w/ increased thyroxine binding protein
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which statement about TSH & T4 in early pregnancy is correct
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TSH fails and thyroid hormones levels rise
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in which case might a very low plasma TSH results not correlated w/ thyroid status
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after high dose corticosteroid treatment
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