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thorotrast
thorium dioxide used as contracts material for radiogram

causes ANGIOSARCOMAS
von-Hippel-Lindau syndrome
autosomal dominant genetic disorder
presents w/ hemangioblastomas
d/t mutation in tumor supressor gene VHL
Kaposi sarcoma
associated w/ Herpes virus 8 in humans infected with HIV
Takayasu arteritis
"pulseless disease"

stenosis of branches of aortic arch

common in young Asian females
Buerger disease
disease in heavy smokers leading to gangrene
Kawasaki disease
affects branches of coronary arteries
Raynaud disease
vasospam of small vessels of fingers and toes
Temporal arteritis
Giant cells

affects the carotid artery
Hypersensitivity vasculitis
manifests with palpable purpura

associated with drugs, food, or infectious agent
Wegener granulomatosis
involves vessels of respiratory tract and kidney
malignant hypertension
kidneys "flea-bitten" b/c multiple hemorrhages on the surface

Microscopically, the glomeruli display fibrinoid necrosis and hyperplastic arteriolosclerosis