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18 Cards in this Set
- Front
- Back
Centrosome
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Attached to outside of the nucleus.
Made up of 2 centrioles. |
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Astral fibres
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Extend from cenromere.
Does not connect with other structures. |
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Pole to Pole fibres
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Connects centrioles.
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Kinetocore fibres
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Connects centriole to kinetocore proteins which bind chromosomes.
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Metaphase Plate
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Mid point between centrosomes.
Chromosomes meet here durin metaphase. |
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Dynesin
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Breaks down microtubule between the kinetocore and (forming) metaphase plate.
This allows the chromosomes to move towards the metaphase plate. |
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Kinesin
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Creates microtubules on the side of the kinetocore closest to the centrosome.
Replaces microtubule broken down by dysein. |
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Cohesin
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Holds sister chromotids together.
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Seperase
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A protease that breaks down cohesin.
Keped inactive until late metaphase. |
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Securin
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A chaperone protein.
Keeps seperase inactive |
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Anaphase Promoting Complex (APC)
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Breaks down securin allowing seperase to activate.
Controlled by CDKs. |
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Cytokinesis
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Cell division.
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Actin fillaments
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Assemble under plasma membrane to form a ring around the metaphase plate.
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Myosin II
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A non-muscle myosin.
Induces contraction of actin ring by causing fillaments to slide over each other. |
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MLC kinase
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Regulates Myosin function when activated.
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ROCK
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Regulates MLC kinase
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Cleavage Furrow
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Furrow in membrane created by contraction of actin ring.
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Cytoplasmic vesicles
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Promotes cell fission by delivering plasma membrane.
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